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86 Cards in this Set

  • Front
  • Back
When capillary filtration exceeds capillary absorption - what might you have?
extracellular edema.
The impulse conduction pathway of the heart is composed of?
modified cardiac muscle fibers.
Sympathetic stimulation of the heart INCREASES contractility by?
increasing calcium stores in the SR
Cardiac output is expressed as a product of?
stroke volume and heart rate
The pulmonary valve prevents blood from flowing back into the?
right ventricle
In the normal cardiac cycle the volume of blood in the ventricle is greatest at?
the end of diastole.
Most tissues regulate blood flow by/to?
maintain constant oxygen availability and by vasodilating in response to adenosine and other metabolic wastes.
A decrease in total peripheral resistance results from?
arteriole dilation
An INCREASE in the frequency of action potentials in the carotid sinus baroreceptor will cause?
decreased heart rate and decreased mean arterial pressure.
Atrial fibrillation is typically associated with?
irregular heart rate
The initial length of cardiac muscle fibers affects the strength of contraction. This statement is fundamental to the idea that the heart must pump out all of the blood that enters it and it is explained by the changes in alignment of actin and myosin in sarcomeres as well as?
Frank-Starling’s Law of the Heart
In the denervated heart adjustments to INCREASED work load are mediated by mechanisms associated with?
increased end diastolic volume
T/F the pressure gradient driving bulk flow of blood decreases from arteries to capillaries to the veins.
TRUE
Both systemic and pulmonary circulations have the same?
flow rate
The PR interval in an electrocardiogram is a reflection on the?
conduction time between the atria and ventricles.
Long term mechanisms to increase a mean arterial pressure that is below normal set point of 100 mm HG invovles?
1. Secretion of ADH by hypothalamus 2. Secretion of renin by juxtaglomerular cells 3. Production of angiotensin II in the lungs and 4. Changes in aldosterone levels.
The rapid rise phase of an action potential recorded from a ventricular cell is due to?
opening of sodium channels
The cell body of a postganglionic neuron that innervates the heart is most often found?
inside the pericardium
Sympathetic postganglionic neuron activity speeds the heart by?
decreasing Pk
Parasympathetic postganglionic neuron activity decrease the force of cardiac contraction by?
decreasing cAMP concentration
In the parasympathetic innervation of the heart postganglionic neurons release a transmitter that has what metabotropic effects on the innervated heart cells?
it decreases cAMP production
The pressure in the cardiovascular system is lowest in the?
veins
A decrease in the mean arterial pressure from 150 to 100 mm HG reduces?
oxygen consumption by the heart. Baroreceptor tell what the blood pressure is. Frequency goes down when the blood pressure drops. CVS #2 ↑ aortic pressure,↓blood being ejected ↓SV. Thus if ↓ aortic pressure then ↑ stroke volume.
The contractility of the heart has increased so there should be a decrease in?
end systolic volume
Frank Starlings Law of the heart states that?
initial length of cardiac muscle fibers affects the strength of contraction
What occurs during isovolumetric ventricular contraction of the heart?
the valves are closed
During the plateau phase of an action potential recorded from a ventricular cell the calcium channels are?
open
Parasympathetic moves the pacemaker away from?
threshold which decreases the heart rate
Dub corresponds to?
closure of aortic and pulmonary valves.
In a normal electrocardiogram the RR interval corresponds to?
The heart rate
Sudden onset ventricular fibrillation decreases?
cardiac output
What is primarily responsible for the low permeability of the blood brain barrier?
presence of tight intercellular junctions in continuous capillaries
An increase in capillary pressure results in an increase in?
the capillary filtration rate
Tissues have an intrinsic ability to regulate their own blood flow. This ability results in an increase in?
blood flow with increased metabolic rate
Total peripheral resistance is controlled by?
the diameter of the arterioles and affects both vascular and cardiac function. A decline can also increase venous return.
Long term regulation of blood pressure is accomplished by?
1. The kidney 2. And relies upon control of blood volume 3. Relies upon the renin-angiotensin system
Edema can occur if the net filtration rate exceeds?
the net absorption rate plus lymphatic flow.
Long term mechanisms to decrease mean arterial pressure that is above normal set point of 100 mm HG invovles?
changes in aldosterone levels
What reduces the likelihood of the formation of edema?
1. Increase in interstitial fluid hydrostatic fluid 2. Increase in plasma protein concentration 3. Decrease capillary hydrostatic pressure
A decrease in TPR results from?
arteriole dilation
Mean arterial pressure can be calculated from?
the pulse pressure
What are some clinical outcomes of Coronary Artery Heart Disease?
1. M.I. 2. Sudden Death 3. Unstable angina
What are modifiable risk factors from CAHD?
1. Hypertension 2. Smoking 3. Diabetes mellitus
A stroke (CVA cerebrovascular accident) is a focal neurological deficit due to?
lack of blood flow/oxygenation
The heart functions to pump out as much blood as it receives. This phenomenon is described by?
Frank Starlings Law of the Heart and the initial length of the cardiac sarcomere affects the strength of contraction.
A patient has a MI resulting in right bundle branch block. What is the possible repercussions of this blockade?
distension of the ne veins (e.g. jugular) is likely to occur.
A patient has a heart transplant. What will likely occur?
The SA node will drive the conduction system of the new heart
The contractility of the heart has increased which immediately results in?
decreased end diastolic volume
Cardiac cells are identical to?
skeletal muscle cells
Sudden onset of atrial fibrillation immediately causes?
ventricular tachycardia??? Or irregular heart rate (there are conflicting answers)
Contractility of the heart relies upon?
calcium levels in the SR
Edema can occur if there is a decrease in?
plasma oncotic pressure
Microcirculation within most tissues relies upon?
1. Fluid filtering out of the capillary on the arterial side and being absorbed into the capillary on the venous side.
The SA node is located in the?
upper outer wall of the right atrium.
Most tissues regulate regional blood flow by?
vasodilation in response to adenosine and other metabolic wastes.
A significant increase in the frequency of APs in the carotid sinus baroreceptor sent to the cardiac center will elicit?
decreased heart rate and decreased mean arterial pressure
An important function of the arterioles is to?
control the entrance of blood into the capillary bed
Long term mechanisms to decrease mean arterial pressure that is above normal set point of 100 mm Hg involves?
changes in aldosterone levels
The mean arterial pressure can be calculated from?
pulse pressure
An increase in the mean arterial pressure from 100 to 150 mm Hg increases?
end systolic volume and decreases cardiac output
Cardiac cells in in the SA node have?
pacemaker potential
The left ventricle contains the maximal amount of blood at the end of?
diastole
What happens right after the end of isovolumetric contraction of the heart?
ejection of blood
The pressure in the cardiovascular system is?
higher in the pulmonary circulation and can be regulated peripheral resistance by varying arteriole diameter.
Increased end-diastolic volume will initially lead to?
an increased stroke volume.
On an ECG repolarization of the ventricles is associated with?
the T wave
Edema is likely to occur if there is a decrease in?
plasma protein concentration
In regards to the pacemaker cell the conduction velocity of conductile cells in the AV node modifies the?
PR interval
An increase in blood volume via an intravenous infusion will increase?
action potential discharge frequency of the aortic baro-receptor.
Sudden onset ventricular fibrillation increases?
venous pressure
A decrease in the mean arterial pressure from 150 to 100 mm Hg increases?
the Cardiac Output.
During the rapid depolarization phase of a cardiac action potential recorded from a ventricular cell potassium permeability is starting to?
decrease
Velocity of flow in blood vessels that are in parallel is inversely related to?
cross sectional area
10. All of the following apply to ischemia
EXCEPT:, A. It represents a reduction in blood flow* B. It is an area of dead or necrotic tissue*
C. It leads to angina
D. It is a consequence of atherosclerotic disease, .
What part of the heart does the left anterior descending coronary artery NOT supply with blood?

A. The area around the apex of the heart

B. The anterior portion of the interventricular septum
* C. The sinu-atrial node*

D. The anterior wall of the left ventricle
* C. The sinu-atrial node*
What is the most common form of medical treatment to reduce the risk for a CVA?
Anticoagulant
When examining the facial nerve sparing of the upper one third of the facial muscle function usually indicates a?
UMN (upper motor neuron) lesion
What tunic in an artery is responsible for vasoconstriction?
tunica media
At any given time the vessel type holding the largest volume of blood is the?
vein
Calcium levels are critical to appropriate cardiac contraction. Cytosolic calcium activates?
the contractile apparatus.
29. During inflammation capillary permeability increases and plasma proteins may leak into the interstitial fluid. Based on these observations which of the following statement is TRUE?
Net absorption increases
24. Long term regulation of blood pressure:
a. is accomplished by the kidney

b. relies upon control of blood volume

c. relies upon the rennin-angiotensin system
d.A,B
e. all of the above, d. A and B.
e. all of the above
During which of the following phases of the cardiac cycle are all cardiac valves OPEN?
a. rapid filling
b. Ejection
c. Isovolumetric relaxation
d. Isovolumetric contraction
e. None of the above
e. none of the above
23. Tissue have an intrinsic ability to regulate their own blood flow. This ability:

a. is related to the vasodilation induced by increased oxygen levels
b. is related to the vasoconstriction induced by metabolic wastes (e.g. adenosine)

c. results in an increase in blood flow with increased metabolic rate
d. is related to the relaxation of smooth muscle in response to stretch
e. none of the above
e. none of the above
26. The heart rate is regulated by several means. Which of the following is CORRECT?

a. Increasing the potassium permeability in the SA node increases the heart rate.

b. Acetylcholine released by the sympathetic nervous system increases heart rate

c. Sympathetic stimulation hyperpolarizes the pacemaker potential which increases the heart rate.
d. Parasympathetic stimulation hyperpolarizes the pacemaker potential which decreases the heart rate.
e. none of the above.
d. Parasympathetic stimulation hyperpolarizes the pacemaker potential which decreases the heart rate
25. Sympathetic stimulation of the heart increases contractility by:
a. Phosphorylation of calcium-activated calcium-release channels in the sarcoplasmic reticulum

b. increasing calcium stores in the sarcoplasmic reticulum

c. Decreasing SERCA (sarcoplasmic reticulum calcium) pump activity
d. Decreasing the time L-type calcium channels are open
e. A B and C
e. ABC