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31 Cards in this Set

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*squamous epithelium
benign
exophytic pedunculated or sessile growth
papillary projections
central core of fibrous connective tissue
**soft palate
tx: excisions, no recurrance
papilloma
*premalignant lesions
white plaque like lesion that CANNOT be rubbed off
cause should be identified and removed
high risk: floor of mouth, ventrolateral tongue, lip
microscopic: hyperkeratosis, epithelial hyperplasia
5-25% show dysplasia
leukoplakia
*premalignant lesion
smooth red patch/ granular red and velvety patch
high risk: floor of mouth, tongue, soft palate
90% show dysplasia
erythroplakia
*premalignant lesions
frequently preceds squamous cell carcinoma
abnormal change may revert to normal if stimulus is removed
abnormal maturation of epithelial cells
hyperplasia of basal cell layer
enlarged pleomorphic nuclei
abrnomarl keratinization
increased # of mitotic figures
epithelial dysplasia
*premalignant lesion
abnormal cells have NOT invaded through the basement membrane
tx: surgical excision and close long term follow up
epithelial dysplasia
*squamous epithelial
malignant
most common in oral cavity
presents as leukoplakia erythroplakia or speckled, or exophytic ulcerative mass
infiltrates and destroys underlying bone
high risk: floor of mouth, ventrolateral tongue, soft palate, tonsillar pillar, retromolar
squamous cell carcinoma
*squamous epithelium
tumor cells invade basement membrane into underlying CT
sheets and nests of neoplastic cells
keratin is variable
hyperchromatic nuclei and numerous mitotic figures
squamous cell carcinoma
what are the TNM staging levels for stage 1, 2 and 3
1: T1NOMO
2: T2N0M0
3: T3N0M0, N1
4: N2, N3, T4, M1
T1? T2? T3? T4?
N0? N1? N2? N3?
M0? M1?
tumor size: 1) -=0-2, 2) 2-4, 3) >4, 4) tumor invades elsewhere
node: 0) no palpable nodes, 1) ipsilateral nodes, 2) bilateral nodes, 3) fixed palpable
Metastatis 0)no, 1)yes
*squamous epithelium
slow growing exophytic tumor
white surface
older men
*vestibule and buccal mucosa
well differentiate epithelium in papillary projections
keratin plugging
broad based rete pegs that penetrate to CT
basement membrane in tact
doesnt metastisize, local damage
verrucous carcinoma
*squamous epithelium
malignant skin tumor
excessive sun exposure
non healing ulcer with rolled borders
basal cells into underlying CT
rarely metastasizes, locally invasive
basal cell carcinoma
*salivary gland
benign salivary gland tumor
most common
**parotid gland, palate
slow growing, non ulcerated, painless
older females
encapsulated, epithelium and CT mixture, CT may contain cartilage and is derived from myoepithelial cells
TX: excise, recurrence varies, possible malignant transformation
pleomorphic adenoma
*salivary gland tumors
benign, Female predilection
**upper lip, buccal mucosa
slow enlargling, non ulcearted, painless
encapsulated, uniform epithelial cells
NO CT-like COMPONENT
tx: excise, no recurrence
monomorphic adenoma
*salivary gland tumor
malignant
*parotid, palate, F>M
slow growing, ulceration, pain is common
microscopically: looks like swiss cheese
cylinders of small darkl staining epithelial cells, few mitotic figures
tx: excise, rucrrence common, metastastis to lungs
adenoid cystic carcinoma
*salivary tumor
malignant
*parotid gland, palate
children-->adults, F>M
most common salivary tumor in kids
mandibular premolar/molar region
uni/multilocular radiolucency
unencapsulated, infiltrating
mucouse cells w squamous like epithelial cells
tx: excision, low grade 92% 5yr survive; high- 50% 5 yr
mucoepidermoid carcinoma
*odontogenic tumor
benign, slow growing but locally agressive
asymptomatic swelling of affected bone
**mandibular molar/ramus
radiolucent, impacted teeth
resembles dentigerous cyst
ameloblast-like epithelial cells, surround areas resembling stellate reticulum, arranged in islands or interconnecting strands
tx: excise, recurrence common
ameloblastoma
benign
females, under 20yo, anterior maxilla, impacted tooh
asymptomatic, local swelling
well circumscribed radiolucent
calcifications/radiopaque areas
encapsulated, duct like structures, whorls and masses
calcifications
tx: enucleation, no recurrence
adenomatoid odontogenic tumor
benign, unencapsulated infiltrating
10-30yo
mandible, multilocular radiolucent, porrly defined margins
tooth displacement
microscopic: resembles papilla
tx: excise, 25% recur w/i 2 yrs
odontogenic myxoma
cementum producing tumor in young adults
pain is common, causes localized bone expansion
well define radiopaque mass, surrounding halo
attached to roots of premolar/molar mandibular
tx: enucleation no recurrence
benign cementoblastoma
most common odontogenic tumor
adolescents and young adults
failure of permanent tooth to erupt
swelling and displacement of teeth
tx: excise no recur
odontoma
compound: multiple little teeth
complex: mass of enamel cementum pulp
benign tumor of mature fat cells
yellow mass, delicate blood vessels on surface, thin epithelium
*buccal mucosa and vestibule
tx; excise no recur
lipoma
benign: nerve tissue
derived from schwann cells
**tongue
1: diffuse schwann cells
2: schwann cells palisaded whorls around central pink zone, encapsulated
1)neurofibromas and
2)schwannomas
benign, neural/mesenchymal cells
painless, non ulcerated nodule
**tongue >buccal mucosa, females
oval shaped cells w granular cytoplasm, surface epi shows hyperplasia
tx: excise no recur
granular cell tumor
benign vascular tumor
possible developmental tumor, limited growth potential
present at birth or soon after
50% cases in head and neck
**tongue, marked macroglossia
females
adults; occur as response to trauma
deep red/blue lesions
1)numerous small capillaries
2) many large blood vessles
tx: spontatneous remission, or inject sclerosing solution
hemangioma
1) capillary hemangioma
2) cavernous hemangioma
benign tumor of lymphatic vessels
present at birth
***tongue
ill defined mass, pebbly surface
multiple lymph vessels w lypmh fluid, vessels close to overlying epithelium
tx: excise, TENDS TO RECUR
lymphangioma
cystic hygroma: lymphangioma of the neck
developmental tumor of melanocytes
skin/oral mucosa, tan/brown, macules/papules
***hard palate >buccal mucosa
20-50yo Female
tx: BIOPSY
melanocytic nevus
malignant tumor of melanocytes
result of sun exposure
rarely intraoral ** palate, max gingiva
poor prognosis
malignant melanoma
bony hard nodule on buccal aspect of alveolar ridges
tx: none unless needs prosthetic
exostosis
benign bone tumor
slow growing, asymptomatic
sharply define radiopaque mass w/i bone
delineated mass attached to outer surface of bone
causes bone expansion
tx: excise no recur
osteoma
malignant tumor of lymphoid tissue
primary lesion in oral soft tissue or bone
**tonsillar area, males
prognosis depends
lymphoma
most cases arise from breast, prostate, lung, thyroid, kidneys
***mandible, males
pain parasthesia swelling bone expansion loose teeth
appears several years after primary lesion, poor prognosis
metastastic tumors of the jaw