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38 Cards in this Set
- Front
- Back
a minor apthae
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Recurrent apthous ulcers (RAU)can sometimes be caused by citric acid, peanuts, milk and beer. Stress seems to make this condition worse.
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True recurrent apthous ulcers only occur where?
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moveable portion of the mucosa.
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Bechet's syndrome
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a multisystem disease usually presenting with ocular, oral and genital lesions. MOst likely seen in females
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Reiter's Disease
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a multisystem disease most commonly found in males. same clinical manifestations a BEchets only arthiritis is included and genital lesions include inflammation of the penis (balanitis).
Treatment is the use of anti-inflammatory drugs |
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Oral manifestations of Major apthae
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large cratered ulcerations of mucosal surfaces with piled up erythamatous margins of long duration; ulcers heal in weeks to months, usually without scarring
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steven-johnsons
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males most likely to get this disease
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Lupus erythematosus
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more common in females. about 50 times moe likely to get this than males. Genetic disorder that is very difficult to diagnose, autoimmune.
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oral manifestaions of lupus
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lesions present as erythmatous plaques or erosion (thinning out not a break)affecting the bucal mucosa, gingiva, palate, and vermillion zone; ulcerations are seen frequently
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lupus
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increased sensitivity to ultraviolet radiation
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erosive (bullous) lichen planus
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a skin disease affecting the basal layer of the epithelium suspected to be autoimmune
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erosive and bullous
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least common; exhibits erythemous erosions ans ulcerations most common on the posterior buccal mucosa and attached gingiva
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bullous lichen planus
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a variant of erosive in which vesicles or bullae precede ulcerations
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wickham's strae
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may be visible at periphery of lesion; may or may not accompany skin lesions
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recurrent apthous ulcers
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painful lesions are evident that are usually less than 5mm in dimension; have a shallow yello fibrinous center with a erythematous nonelevated margin
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Treatment for RAU
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palliative, multiple and frequent recurrence may respond to supervised steroid therapy; topical tetracycline reduces the likelihood of a secondary bacterial infection; recurrence is likely
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treatment for BEchet's syndrome?
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supervised steroid therapy, but may undergo spontaneous remission
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Periadenitis Mucosa Necrotica Recurrans (PMNR)
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Major apthae or Sutton's disease; considered to be an immune dysfunction
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Erythema multiforme
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a disease affecting the skin and mucous membranes.suspected to be caused by an immune dysfunction
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Steven-johnson's syndrome
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a multisystem disease of erythema multiforme usually involves ocular, oral and genital regions. (you must have all three of these symptoms to have this disease)
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treatment for Steven-Johnson's
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supervised steroid therapy with possible recurrence
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lupus
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considered a connective tissue disease(autoimmune stimulant= nuclie)
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recurrent apthous ulcers
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lesions are usually single, but may occur in crops; adjacent lesions may coalesce to form larger areas of ulceration; usually heal in 7-10 days without scarring; multiple and multisystem lesions may be suggestive of BECHET's syndrome
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shallow necrotic center with red margin
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RAU
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clinical manifestaions of BEchet's syndrome?
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*oral lesion- resemble RAU and tend to occur in multiple crops
*ocular lesions- include uveitis and/or conjunctivitis *genital lesions-also exhibit painful lesions |
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Major apthae treatment:
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supervised steroid therapy
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erythema multifrome
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lesions may exhibit multiple RAU-type or larger ulcerations; vescicles may occur early or exist at the margins of the ulcers
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erythema multiforme
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a classic skin lesion presents as multiple concentric cirlce of erythema and normal skin color.
Treatment is supervised steroid therapy with possible recurrence |
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steven-johnson's
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oral and genital lesions usually exhibit erythema multiform; ocular lesions consist of conjunctivitis or uveitis
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name the two types of lupus
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chronic: affects the skin and mucous membranes (butterfly rash)
systemic: a multisystem disease that is occasionally fatal affects all internal organs you can have both types of these |
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clinical manifestations of lupus
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antibodies are formed against the cell nucleus or other cytoplasmic antigens, patients often complain of malaise, weakness and an occasional low-grade fever
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what are the forms of erosive lichen planus
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erosive and bullous, bullous lichen planus and wickham's striae
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treatment for erosive lichen planus
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steroid therapy, may undergo spontaneous remission with possible recurrence
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Pempigus (pemphigus vulgaris, pemphigus vegetans)
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a skin disease in which there is shedding of the skin. It attacks the desmosomes(they hold the epithelial together)
autoimmune; histologically an intraepithelial separation (above the basil layer) with Tzanck cells (free floating epithelial cells only seen in this disease)resembles a fried egg with a yolk in the middle |
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oral manifestations of pemphigus
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lesions present as apthae-like ulcerations or large irregular ulcerations with erythamous margins; vescicles or bullae may precede ulcerations. intraepithelial split
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clinical manifestations of pemphigus
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*antibodies are directed against desmosomes resulting in acantholysis(loss of cell to cell adhesion)
*individuals may exhibit a positive nikolsky sign (sloughing of epithelium after minor trauma) *may have an ethnic or genetic predisposition; treatment- use of steroids |
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pemphigoid {benign mucous membrane pemphigid, cicaticial-(scar forming) pemphigoid}
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an autoimmune disease which effects the basil layer membrane area, antibodies are directed against hemidesmosomes resulting in subepithelial separation. Only affects mucosa
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oral manifestations of pemphigoid
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lesion exhibit painful ulcerations with erythematous margins on any mucosal surface
* desquative gingivitis- a clinical description of possible pemphigoid, positive nikolsky sign is frequently notes |
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clinical manifestations of pemphigoid
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bullous pemphigoid is considered a variant of cicatricial pempigoid, but autoimmune findings are not consistent.
Treatment use of steroids, may undergo periods of remission and exacerbation |