Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Thiazolidinediones
Biguanides |
Drugs that sensitize the body to insulin and/or control hepatic glucose production
|
|
|
Sulfonylureas
Meglitindes |
Drugs that stimulate the pancreas to make more insulin
|
|
|
Alpha-glucosidase inhibitors
|
Drugs that slow the absorption of starches
|
|
|
Thiazolidinediones
|
-decrease insulin resistance by making muscle and adipose cells more sensitive to insulin. Also surpress hepatic glucose production
-6 weeks for maximum effect, takes awhile to get into blood stream to be effective -reduce A1C 0.5-1.0% -Actos,Avandia |
|
|
Biguanides
|
decrease hepatic glucose production and increase insulin-mediated peripheral glucose uptake
* no specific affect on blood pressure, no weight gain, possible weight loss -metformin(Glucophage) |
|
|
Sulfonylureas
|
increase endogenous insulin secretion
*generally the least expensive class of medication -glipizide(Glucotrol), |
|
|
Meglitinides
|
stimulate insulin secretion (rapidly and for a short duration) in the presence of glucose
*safe at higher levels of serum Cr than sulfonylureas -repaglinde(Prandin), nateglinide(Starlix) |
|
|
Alpha-glucosidase Inhibitors
|
block the enzyme that digest starches in the small intestine
*taken with first bite of the meal *no weight gain * GI side effects monitored *look @ liver function b/c contraindicated w/ GI problems or renal dysfunction -acarbose(Precose), miglitol(Glyset) |
|
|
Treatment of type 2 Diabetes
|
diagnosis --> Therapeutic Lifestyle Change --> Monotherapy --> Combination Therapy (oral drugs only) --> combination therapy (oral drugs with insulin)
|
