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22 Cards in this Set

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What are glycoproteins involved with in protections?
1. lubrication of food, mucosa, teeth
2. waterproofing of mucosa: mucin (a glycoprotein)
3. barrier against irritants and toxins in food and microorganisms: mucin
4. lavage/washing action removed bacteria from teeth
What purpose does phosphate and bicarbonate serve in saliva?
1. Maintain pH unsuitable for bacterial colonization.
2. Neutralize acid produced by bacteria.
This also helps in neutralizing esophageal contents.
What functions does salive have in digestion?
1. Formation of food bolus: water
2. Neutralization of esophageal contents: phosphate and bicarbonate
3. Digestion of carbohydrates: amylase
4. Digestion sof fats: lipase made by serous glands of Von Ebner
What functions does saliva have in taste?
1. solution of molecules: water
2. taste bud growth and maturation: gusten
What functions does saliva have in antimicrobial activity?
1. lysozyme: hydrolyzes bacterial cell walls
2. Lactoferring: binds iron and withholds it from bacteria
3. salivary peroxidase: inhibits growth of bacteria by generating oxidizing agents
4. IgA antibody: agglutinates bacteria and inhibits human immunodeficiency virus
What purpose does saliva have in maintaining tooth integrity?
Calcium and phosphate promote maturatin and remineralization.
Saliva plays what type of role in regulatory proteins?
Production of growth factors and other regulatory proteins such as nerve growth factor and vasoactive peptides.
What can xerostomia cause and causes of it(dry mouth, insufficient saliva)?
1. Causes of serostomia: aging, medications, radiation therapy, systemic diseases
2. Effects of serostomia: difficulty eating, speaking, wearing dentures, oral mucosal ulcers (sores); increased caries, candidosis
What is required for the development of salivary glands?
1. A downgrowth of oral surface epithelium
2. Ectomesenchyme
What is stroma?
Connective tissue framework of salivary glands
What is significance of stroma?
1. Capsule of dense irregular connective tissue
2. Septa of fibrous connective tissue divide gland into lobes and lobules
3. connective tissue carries blood vessels, nerves and ducts
What is parenchyma?
Functional part of salivary glands.
What is significant of parenchyma?
1. Secretory units (alveoli)
a. spherical unit (acinus)
b. tubule- composed of mucous cells. Larger than central lumen
c. tubule of mucous cells capped by a serous demilune. Secretion of serous cells reaches the central lumen via intercellular canaliculi
What are myoepithelial cells?
secretory system, (gleeking- shooting of saliva); somewhat involved in tumors
Serous cells secrete by?
Exocytosis (merocrine mode) into the central lumen.
Parotid gland summary
ducts within lobules are intercalated and striated; ducts between are interlobular; secretory units are all serous
submandibular glands summary
ducts within lobules intercalated and striated; ducts between interlobular (all are); more serous than mucous
sublingual glands summary
ducts within lobules are intralobular; ducts between interlobular; more mucous than serous
minor glands
ducts within intralobular, ducts between interlobular; secretes mucous excepts serous glands of Von Ebner
Intercalated ductos of the parotid and submandibular glands produce what?
lysozyme and lactoferrin
Striated ducts of the parotid and submandibular glands do what?
reasorb sodium and excrete potassium
Mucous secretions secretions are?
thick and sticky, consisting of glycoproteins and incrased carbohydrates and decreased enzyme content compared to serous secretion