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5 Cards in this Set
- Front
- Back
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Sulfonylureas
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mechanisms: Big SE
increase release of insulin Hypoglycemia increase receptor sensitivity Examples: (end in 'ides') Tolazamide (Tolinase), Glyburide (Diabeta), Glimepiride (Amaryl) |
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BIGUANIDES
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Mechanisms:
Decrease liver conversion of glycogen decrease insulin resistance BIG SE: (less likely) for hypoglycemia do not give if contrast medium Examples: Metformin (Glucophage), Ive contrast dye --> injection cannot give metformin-12-24 hrs before contrast --> can cause serious vascular damage |
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ALPHA-GLUCOSIDASE
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Mechanisms:
slows carb digestion Big SE: hypoglycemia (less likely) Examples: Acarbose (Precose), Miglitol (Glyset) |
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THIAZOLIDINEDIONES (do not use these as much anymore)
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Mechanisms:
Increase sensitivity to insulin Decrease creation of glucose Big SE: Fluid retention Wt. Gain Liver toxic Examples: Rosiglitazone (Avandia), Ploglitazone (Actos) |
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MEGLITINIDES
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Mechanisms:
Increase release of insulin Big SE: Hypoglycemia Examples: Nateglinide (Starlix), Repaglinide (Prandin) |
