• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/38

Click to flip

38 Cards in this Set

  • Front
  • Back
What are the three opioid receptors?
Mu
Kappa
Delta
What receptors do opioid analgesics activate?
Mu with weak Kappa
Mu receptors produce _____.
Analgesia, Euphoria, Sedation, and Physical Dependance
Kappa receptors produce ___.
Analgesia and sedation
What are agonist-antagonist opioids?
Produce analgesia
Can antagonize analgesia produced by pure opioid
What is the prototype strong opioid analgesic?
Morphine
Morphine is a ____.
Strong opioid analgesic
How does morphine work?
Mimicking the actions of endogenous opioid peptides
What are the adverse reactions of morphine?
Respiratory Depression
Constipation
Orthostatic Hypotension
Urinary Retention
Emesis
Elevation of Intra cranial Pressure
Miosis (Pupillary constriction)
Sedation
Cough Supression
Cross-tolerance exists among the opioid agonists
T or F
True
Is the withdrawal syndrome from opioids dangerous?
No
What is Fentanyl?
Strong opioid analgesic
What is the prototype drug for mild to moderate pain?
Codeine
Codeine is a _____.
Mild to Moderate opioid analgesic
Oxycodone is similar in action to _____.
Codeine
Agonist-Antagonist Opioids have a (high/low) potential for abuse, produce (more/less) respiratory depression, and are (more/less) powerful.
low
less
less
Pentazocine is a ____.
Agonist-Antagonist opioid
What is the prototype for the agonist-antagonist opioids?
Pentazocine
Pentazocine is a antagonist at ___ receptors.
mu
How is it possible to avoid withdrawal syndromes?
Withdrawal of opioid slowly
Physical Dependence is the same as addiction.
T or F
False
What is a PCA?
Patient-controlled analgesia
What is the opioid of choice for obstetric use?
Meperidine (strong opioid analgesic)
What is the prototype for opioid antagonists?
Naloxone
Physical Dependence is the same as addiction.
T or F
False
What is Naloxone?
Opioid antagonist
What is a PCA?
Patient-controlled analgesia
Tramadol is a ____.
Non-opioid centrally acting analgesic
What is the opioid of choice for obstetric use?
Meperidine (strong opioid analgesic)
What is the prototype for opioid antagonists?
Naloxone
What are the actions of Tramadol?
Weak agonist at mu receptors
Blocks uptake of NE and 5-HT
What is Naloxone?
Opioid antagonist
Clonidine is a _____.
Alpha 2 agonist
Tramadol is a ____.
Non-opioid centrally acting analgesic
Clonidine is used for pain relief.
T or F
True
What are the actions of Tramadol?
Weak agonist at mu receptors
Blocks uptake of NE and 5-HT
Clonidine is a _____.
Alpha 2 agonist
Clonidine is used for pain relief.
T or F
True