Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/26

Click to flip

26 Cards in this Set

  • Front
  • Back
Morphine MOA includes:
- Interact w/opioid receptors
- decr release of substance P
- inhibit releasing NT carrying painful stimuli
- acts on CNS
Morphine AE*:
-euphoria
- emesis
- respiratory depression
- cardiovascular hypotension
- histamine release
in addition to being an analgesic, morphine is also a...
anti-tussive
merperidine MOA:
- interacts with opioid receptors
merperidine AE:
- hepatic metabolism --> noremperidine --> CONVULSIONS

- anxiety, tremor, muscle twitches
methadone MOA:
MOA similar to morphine but LESS EUPHORIA, LONGER DURATION OF ACTION
methadone indications:
--controlled w/drawl of substance users
methadone AE:
physical dependence
fentanyl indications:
anesthesia --100xs more potent than morphine
fentanyl MOA:
-rapid onset (2-5 min) & short duration
Routes of administration for fentanyl are:
intrathecal
epidural
IV
oral (lollipop)
transdermal patch
codeine MOA:
less potent than morphine

less euphoria
less addictive
codeine indications:
- pain --use in combo with ASAP/ASA

- anti-tussive (OTC preparations)
codeine AE:
constipation (need to treat this as well)
oxycodone MOA:
codeine analog --
oral prep --combine w/APAP and ASA
oxycodone indications:
good alternative to morphine
propoxyphene MOA:
derivative of methadone (MOA similar to morphine --less euphoric & longer duration of action)
propoxyphene indicatiosn:
- weak analgesic
- used in combo with APAP/ASA
- post pardum depressum
propoxyphene AE:
- nausea
- anorexia
- constipation
- Toxic: confusion, hallucination, convulsion, respiratory depression
tramadol MOA:
central acting analgesic

metabolism --active metabolite
tramadol indications:
mild or moderate pain
(not for chronic use)
tramadol AE:
- nausea/vomiting, dizziness

- dry mouth
- sedation
- headache

Drug interactions: SSRIs/TCA
Name opioid antagonists:
naloxone

natrexone
Naloxone and Natrexone MOA:
- block opioid receptors
- rapidly reverse effect of opioid receptor
- precipitate symptoms opiate withdrawl
Naloxone indications:
- quick reverse of coma/respiratory depression of opioid overdose

- fast acting

- precipitate symptoms of opiate withdrawl*
Natrexone indications:
similar to Naloxone

-longer duration of action
- used in rapid opioid detox