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8 Cards in this Set
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Opiod Agonist Prototype Drug: |
Morphine Others include: -Fentanyl (Sublimaze) -Hydromorphone (Dilaudid) -Meperidine (Demerol) -Methadone (Dolophine) -Codeine, Oxycodone (Oxycontin) |
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Opioid Agonist expected pharmacological action: |
They act on Mu receptors, and to a lesser degree kappa receptors. The activation of Mu receptors leads to analgesia, respiratory depression, euphoria, and sedation. |
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Therapeutic Uses of Opioid Agonists: |
-Releif of mod.-severe pain -Sedation -Reduction of bowel motility -Codeine- cough supression |
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Routes of administration for Opioid Agonists: |
Routes vary for all |
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Opioid Agonist Side and Adverse Effects: |
-Respiratory Depression (stop if RR drops below 12/min, and have narcan resuscitication equipment ready) -Constipation (Administration of a laxative) -Orthostatic Hypotension -Urinary hesitancy, retention (monitor I/O) -Sedation (avoid driving) -Emesis |
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What is the Opioid overdose triad: |
Coma, respiratory depression, and pinpoint pupils. |
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Contraindications for opioid agonists: |
-Morphine contraindicated for premature infants -Use cautiously with people who have asthma, hepatic and renal disease, IBS, Obese pts. |
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Nursing Adminstration when giving these meds? |
-Check clients pain level on a reg. basis -Take baseline vitals (RR below 12 discontinue) -Double check opioid doses with another nurse prior to administration -Have naloxone (narcan) ready -Warn clients not to increase dosage -Opioids work better on a fixed schedule -Dosage should be tapered
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