Opiods

Front 1

Which opioids cause analgesia?

Back 1

All

Front 2

Which opioids cause increased appetite

Back 2

All

Front 3

Which opioids cause decreased GI motility

Back 3

Mu Kappa

Front 4

Which opioids cause sedation?

Back 4

Mu, Kappa

Front 5

Which opioids cause miosis/mydriasis?

Back 5

Mu, Kappa

Front 6

Which opioids cause immunomodulation?

Back 6

Mu, Delta

Front 7

Which opioids cause Euphoria?

Back 7

Mu

Front 8

Which opioids cause Antidiuresis?

Back 8

Mu

Front 9

Which opioids cause decreased urine voiding reflex?

Back 9

Mu

Front 10

Which opioids cause decrease uterine contraction?

Back 10

Mu

Front 11

Which opioids cause respiratory depression

Back 11

Mu

Front 12

Which opioids cause nausea/vomiting/decrease biliary secretions?

Back 12

Mu

Front 13

Which Opioids cause diuresis/

Back 13

Decreased ADH release
Kappa

Front 14

Opiods are used for

Back 14

decrease diarrhea, antitussive, analgesia, sedation, calming/euphoria, immobilization/chemical restraint, inhibit GI motility, increase locomotor activity

Front 15

Mu agonists

Back 15

Max - Morphine,
Hydropmorphone
Codeine - rarely used in vet med: less potent
Fentanyl
Submax - Buprenorphine - partial
Tramadol, Butorphanol (partial)

Front 16

Kappa agonist

Back 16

Butorphanol
Nalbuphine

Front 17

Mu, Kappa, Delta Antagonists

Back 17

Naloxone - all partial mu
Natrexone - partial @ all receptors

Front 18

Morphine is

Back 18

Mu agonist
used for analgesia/premed/sedative

Front 19

Hydromorphone

Back 19

Mu agonist
More potent than morphine, increased lipophilicity, less emetic

Front 20

Codeine

Back 20

rearely used in vet med; less potent Mu agonist

Front 21

Fentanyl

Back 21

Mu agonist
Minor CV effects, but dose-dependent respiratory depression

Front 22

Buprenorphine

Back 22

Mu agonist
analgesia, sedation, euphoria, GI effects, resp depression

Front 23

Tramadol

Back 23

Mu agonist - SSNRI
antitussive, sedation, nausea, vomiting.

Front 24

Butorphanol

Back 24

Kappa agonist - partial mu agonist
well tolerated in horses
mild/moderate analgesia
antitussive in dogs

Front 25

Nalbuphine

Back 25

Kappa agonist - partial antogonist of Mu
Avoids Mu side effects
Mild to moderate pain

Front 26

Naloxone

Back 26

All receptors (partial Mu)
Use in opioid overdose

Front 27

Natrexone

Back 27

partial all receptors
reverse anesthetic property of opioid

Front 28

Federal agency that regulates controlled substances?

Back 28

DEA
Schedule 1 the most addictive

Front 29

What opioid is only a mu agonist

Back 29

Fentanyl

Front 30

What opioid is only a partial Mu agonist

Back 30

Buphrenorphine

Front 31

What is a mu agonist, serotonin, and norepi reuptake inhibitor

Back 31

Tramadol

Front 32

What is a partial Mu agonsit and full Kappa agonist?

Back 32

Nalbuphine

Front 33

To get analgesia w/o respiratory effects use

Back 33

K agonist
Butorphanol, and Nalbuphine

Front 34

Mu receptor activation causes

Back 34

Analgesia
Decreased Resp, GI motility, Biliary secr, Urine voiding reflex, Uterine contractions
Increased appetite,
Sedation
Euphoria
Antidiuresis
Miosis, mydriaisis
Nausea, vomiting
Immunomodualtion

Front 35

K receptor activation causes

Back 35

Analgesia
Decreased GI motility
Increased appetite
Sedation, Diuresis
Miosis/mydriasis

Front 36

Delta receptor activiation causes

Back 36

Analgesia
Increased appetite
Immunomodulation

Front 37

Mu receptor antagonists

Back 37

nalbuphine, naloxene, naltrexone

Front 38

K receptor antagonists

Back 38

Naloxene, naltrexone

Front 39

Delta receptor antagonist

Back 39

Naloxone, naltrexone

Front 40

The opioid receptors are located

Back 40

in the CNS

Front 41

Opioids inhibit

Back 41

voltage gated Ca2+ channels