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19 Cards in this Set
- Front
- Back
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Diffuse KP
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DDx: Fuchs, sarcoid, syphilis, kerato uveitis, herpetic iridocyclitis, toxo
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stellate KP
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Fuch’s 15% bilateral w/out obvious heterochromia; no synechiae; loss of iris crypts/detail; plasma cells & lymphocytes in ciliary bocy; may have CR scars c/w prior toxoplasmosis; nongranulomatous; gonio: abn vessels (does not develop NVG); complication: Paracentesis-->small, splinter shaped filiform hemorrhage in the angle
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Non-granulomatous histo
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lymphocytes & PMNs
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Granulomatous KP
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iris nodules, mutton fat KP, epithelioid cells; DDx: sarcoid, syphilis, TB, leprosy, brucellosis, coccidiomycosis, lyme, toxoplasmosis, herpetic, lens induced, VKH, MS
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Mutton fat KP histo
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macrophages (“Big Mac=Mutton Fat”)
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Khoudadoust line
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linear KP assoc w/ allograft corneal rejection
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Most common cause of non-infections hypopyon uveitis
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B27
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Hyphema: DDx
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JXG, leukemia, HSV, trauma, ROB, PHPV, Coats, Rb, UGH
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VKH
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bilateral panuveitis, disc edema, multiple serous detachments; pigment changes=chronicity;
DX of exclusion (r/o TB, syphilis, SLE, uveal effusion syndrome); TX=systemic steroidsgood prognosis; IVFA=multiple pinpoint areas of hyperfluorescence w/ gradual leakage into subretinal space; 75%=Sugiura sign (perilimbal vitiligo of iris) |
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Reiters
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urethritis, conj, arthritis,
keratoderma blennorrhagicum (20%)(hand lesions), iritis, keratitis, balanitis, prostatitis, cystitis, sphdylitis, fasciitis, tendonitis, oral lesions, diarrhea; seems to follow dysentery or non-gonococcal urethritis; ureaplasma, chlamydia, shigella, salmonella, yersinia |
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JRA
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typical: girls, >2, iridocyclitis assoc w/ pauci, (80%) ANA+, RF -; lower joints only, incr risk of iritis; rash/fever rarely assoc w/ iritis; joint pain must precede iritis; only AC involvement of eye
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Pauci early JRA
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(most common (90%))
girls, chronic iritis, RF-/ANA+ |
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Pauci late JRA
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boys, acute iritis, RF-/ANA-/75% B27 +
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Stills JRA
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60% boys, rare iritis, RF-/ANA-; severe extraarticular manifestations
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RA
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painless corneal melt & scleromalacia perforans; Tx=glue then po steroids & immunosupression
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Behcet’s
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HLAB5; bilateral ant/post uveitis w/ recurrent explosive inflamm episodes ranging from 2-4 wks w/ nongran ant uveitis w/ “quiet” hypopyon, recurrent vascular occlusive episodes w/ retinal heme; typically no choroiditis
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Behcet's rash
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resemble erythema nodosum (ant surface of legs)—resolve over weeks; acne, folliculitis, thrombophlebitis; also, aphthous & genital ulcers, interstitial lung changes; *Pathognomatic CXR=Pulm art aneurysm
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behcetine skin test
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puncture skin-->pustule at puncture site w/in minutes; Tx=steroids, cytotoxic agents (chlorambucil), cyclosporine; PO steroids, does not completely arrest long term ocular inflammation; colchicines inhibits leukocyte migration-->prevent recurrences;
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Birdshot
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~45y/o; autoimmune (HLA A29); bilateral posterior uveitis; peripheral creamy choroidal infiltrates, peripheral VF loss, nyctalopia, abundant floaters/flashes, chorioretinitis, papillitis, vasculitis, vit cell, CME, loss of color vision, rod dysfxndec scoptopic response on ERG; very poor prognosis (resistant to tx); to slow course, immunosuppresion w/ steroid sparing drugs; daclizumab (monoclonal antibody) may help some w/ inflammation, but visual loss still ensues as visual loss not completely due to inflammation
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