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71 Cards in this Set
- Front
- Back
- 3rd side (hint)
Nitroglycerin (Nitrate)
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Venodilator when < 100 mc
also some arterial dilation when > 100 mc. Decreases preload |
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Nitroprusside (Nipride)
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mostly arterial dilator. Decreases afterload
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Nitroglycerin dose
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open hearts: 10 - 100 mc/min
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Nipride dose
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open hearts: 0.3 - 5 mc/kg/min
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Hydralazine (Apresoline)
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direct peripheral arterial dilator
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hydralazine dose
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5 - 20 mg IVP q 4-6 hrs
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list some colloids
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blood, albumin, hexstend
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list some crystalloids
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salines, LR, Dextrose's
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What advantage does LR have over other crystalloids
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it acts as a buffer, corrects acidosis
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Milrinone (Primacor)
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peripheral arterial and venous dilator, decreases preload and afterload.
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Primacor dose
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Usually a bolus (not a gtt). 50 mc/kg
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Brevibloc (esmolol)
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Beta blocker (thus antiarrythmic too). Decreases contractility, heart rate and BP (decr. renin)
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Cleviprex/clevidipine
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Calcium channel blocker. Decreases afterload (vasodilates peripheral arterial and coronary), contractility, heartrate
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Brevibloc dose
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50 - 300 mc/kg/min
initiate for HR > 120 if SBP > 110 |
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Dobutamine
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B1 and mild B2 and alpha.
Increasing dose exponentially increases effect. Increases CO, HR and contractility. Decreases SVR |
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Dobutamine doses
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open heart: 5 - 10 mc/kg/min
regular: 2-40 mc/kg/min |
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dopamine
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low doses stimulate dopamine receptors, higher stimulate alpha and B1
low dose: kidney dilator med dose: B1 high dose: alpha and B1 |
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dopamine dose
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Open heart: 2-7.5 mc/k/min
regular: 1-2mc/k/mi: renal 2-10mc/k/min: increase CO, SVR anad preload >10: marked vasoconstriction (alpha) |
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Norepinephrine (Levophed)
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Alpha and Beta 1
Increased contractility and vasoconstriction (nonselective)...so last resort drug |
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Levophed dose
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8 - 12 mc/min
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Epinephrine
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Stimulates alpha and all betas
"selective vasoconstrictor: doesn't effect brain, heart, skeletal muscle-shunts blood.....thats why its code drug!) |
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epinephrine dose
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open heart: 0.02 - 0.2 mc/kg/min
regular: 1-20mc/min |
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neosynephrine
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pure alpha, peripheral vasoconstriction
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neo dose
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regular 40-200 mc/min
open heart: 20-50 mc/min |
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vasopressin (pitressin)
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same as ADH
peripheral smooth muscle vasoconstriction and water reabsorption |
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vasopressin dose
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40 units IVP in arrest
0.01 - 0.04 units/min |
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protamine
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reverses heparin
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protamine dose
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25-50 mg IVP (usually given in OR)
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Amicar
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antifibrinolytic, preserves platelets and decreases blood loss in post operative bleeding
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Factor VII
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last resort post operative bleeding after blood has been administered. Systemic clotting! Watch CT's!
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Brevibloc (esmolol) when to initiate...
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beta blocker (B1 and B2)
initiate for HR > 120 if SBP is > 110 |
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Esmolol gtt dose
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50 mc/k/min - 300 mc/k/min to maintain HR < 120
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Esmolol when to notify MD
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notify before intiating
Notify if near max dose notify with onset of 2nd/3rd degree HB |
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milrinone (Primacor)
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usually just bolus,
incr. contractility and peripheral vasodilator (arterial & venous) |
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milrinone (Primacor) dose
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50 mc/kg
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Calcium channel blockers: list em
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norvasc
cleviprex cardizem nicardepene (cardene) Procardia verapamil |
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Ca channel blocker
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decreases afterload (SVR), decr. contractility, decr. HR, vasodilates (peripheral artery and coronary)
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Beta 1 vs Beta 2
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heart and kidnyes is B1
B2 is bronchial & vascular smooth muscle dilator |
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strict Beta 1's
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metropolol
atenolol esmolol |
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Nitro bag concentration
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50 mg/ 250
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nitroprusside concentration
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50 mg/ 250
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dobutamine concentration
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250 mg /250 ml
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dopamine concentration
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400 mg/250 ml (1600 mc/ml)
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norepi (levo) bag concentration
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4 mg/ 250 ml (16 mc/ml)
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epi bag concentration
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2 mg/ 250 ml (8mc/ ml)
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Neo bag concentration
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20 mg/ 250 ml (80 mc/ml)
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Vasopressin bag concentration
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50 units/ 250 ml
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Esmolol (Brevibloc) bag concentration
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2.5 mg/ 250 ml (10 mc/ml)
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Open heart target SBP
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90-120
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Open heart target SVR vs. normal
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800 - 1400 (normal 900 - 1300)
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Open heart target PAD vs. normal
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10 -15 (normal 6 - 12)
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Open heart target PCWP vs normal
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10-15 (normal 8-12)
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Open heart target Cardiac index
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> 2 (normal 2.5 - 4)
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open heart target urine output
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> 30 ml/hr
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open heart target SV02
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> 65 % (normal 60 - 80%)
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open heart target CVP
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8-12 (normal 2-8)
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SVO2
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mixed venous oxygen saturation
the % of oxygen bound to hgb returning to right side of heart especially useful if measured before and after changes are made to vent/gtts etc. Tells us if tissues are getting enough oxygen |
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what does low SVO2 mean? high?
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tissues are extracting more O2 than normal
a rise in SVO2 is usually good unless there is a concurrent rise in lactic acid (anaerobic metabolism!) |
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per standing orders, when would one want to initiate dopamine gtt? what gtt would you add next if ineffective?
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HR < 100
SVR < 800 SBP < 90 if more required add epinephrine infusion |
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Per standing orders, when would one initiate epinephrine gtt?
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HR < 100
SVR < 800 SBP < 90 titrate to keep SBP > 90 |
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per standing orders, when would I initiate Nicardipine (Cardene) infusion?
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SBP > 120
titrate for SBP 90 - 120 |
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nicardepene (cardene) dose
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1 mg/hr, max dose 12 mg/hr
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per standing orders, when could I initiate Cleviprex gtt?
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SBP > 120, titrate for SBP 90 -120
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Cleviprex gtt dosing
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2 mg/hr, max 10 mg/hr
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Per standing orders, when could I initiate Nitroglycerin gtt?
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SBP > 120, titrate SBP 90-120
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Per standing orders when could I initiate Brevibloc (esmolol)?
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Notify surgeon first
initiate for HR > 120 only if SBP > 110 to maintain HR < 120 |
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Per standing orders, when could I initiate dobutamine gtt?
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Notify surgeon first
initiate for CI < 2 SVR > 1400 SBP < 90 titrate to keep SBP > 90 |
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Per standing orders, when could I initiate phenylephrine (neo) gtt?
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notify surgeon before initiating
for SVR < 800 titrate for SBP > 90 |
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Per standing orders, when can I initiate amiodarone gtt?
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Notify surgeon first
for new onset a -fib |
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Per standing orders, when can I give sodium bicarbonate?
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1 amp IV q hour PRN for pH < 7.32
and base excess < -5 in addition to vent changes to correct acidosis |
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3 vaso gtts that are in mc/min
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Neo
Norepi (levo) Nitro |
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