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42 Cards in this Set
- Front
- Back
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used as malaria prophylaxis, and used for extra-erythrocytic forms of Plasmodium vivax or P. ovale
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Primaquine
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quinolone derivative
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Ciprofloxacin
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PABA structural analogs. inhibit folic acid synthesis.
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sulfonamides
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shoudl not be used in anuric pt due to production of negative nitrogen balance and inc. BUN levels.
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Tetracyclines (doxycycline is the exception)
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3rd generation cephalosporin,& DOC for bacterial meningitis in kids (ie HiB), & one does treatment of gonrrhea
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ceftriaxone
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DOC for hepatic coma
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neomycin (aminoglycoside) it suppresses the normal flora -->dec NH4 production -->dec free nitrogen levels in the bloodstream
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irreversible inhibitor of Beta lactamases, but not of transpeptidase, so use with a Beta lactamase sensitive penicillin.
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Clavulanic acid
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treatment for pseudomonas aeruginosa & klebsiella. broad spectrum antibiotic
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piperacillin
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treatment for mycobacterium tuberculosis
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streptomycin (aminoglycoside)
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most commonly used drug for TB, usually combined w/ Rifampin and/or ethambuto. pre treat w/ pyridoxine (vit B6) can prevent peripheral neuritis
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Isoniazid
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treatment of hookworm disease. it is a depolarizing NMJ inhibitor
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pyrantel pamoate
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Buy "AT" 30, "CELL" at 50
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A= Aminoglycoside
T= Tetracycline C= Chloramphenicol E= Erythromycin (macrolide) L= Clindamycin L= Lincomycin |
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treatment for intraabdominal infections (ie w/ Bacteroides fragilis.
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Cefoxitin
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broad spectrum antibiotic. bone marrow depression (common)- aplastic anemia (rare)
gray baby syndrome, DOC typhoid fever, DOC HiB meningitis in kids |
Chloramphenicol
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treatment for trypanosomiasis
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Nifurtimox
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treatment for leishmaniasis & amedbiasis. good for anaerobic bacteria= Bacterioides fragilis. DOC trichomoniasis. DOC giardia lamblia
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Metronidazole
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treatment for P. Carnii
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TMP-SMX and Pentamidine
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drug used to treat Brucellosis and Cholera as well as RMSF and spirochete infections (ie Borrelia burgdorferi =lyme disease)
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Tetracycline
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inhibitor of dihydrofolate reductase activity
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TMP-SMX
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long duration of action = so given once every 3-4 weeks for treatment of Syphilis
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Benzathine Penicillin G
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treatment for Schistosomiasis (trematode (fluke) infections)
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Praziquantel
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treatment for Trypanosomiasis that has neurological symptoms
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Melarsoprol
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treatment for Leishmaniasis
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Stibogluconate
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treatment for fungal encephalitis
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Fluconazole
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polyene antifungal
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Amphotericin B
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inhibitor of fungal ergosterol synthesis so disrupts fungal membrane
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Kotoconazole
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accumulates in keratinized layers of the skin so it is used in dermatomycoses infections
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Griseofulvin
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anti-malarial treatment for Chloroquine resistant strains of P. falciparum
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Mefloquine
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treatment for malaria when it is inside the RBCs
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Chloroquine
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DOC for Chagas disease due to Trypanosoma cruzi
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Nifurtimox
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used in pts allergic to penicillins
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Erythromycin
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topical treatment of superficial mycotic infections like Candidiasis
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Nystatin
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guanine analog that is used to treat Herpes infections
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Acyclovir
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used with Cilastatin. this drug can cause seizures
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Imipenem
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bleeding due to vit K level alterations. contraindicated in pts w/ bleeding disorders
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Cefoperazone
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used for MRSA. can cause "red neck" due to facial flushing from histamine release.
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Vancomycin
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used with Cilastatin. but does not cause seizures as Imipenem did.
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Meropenem
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only penicillin that does not need dose adjustment in renal impairment
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Nafcillin
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what is the side effect that the following drugs all share: Metronidazole, Isoniazid,Vincristine, ddI, AZT or Allopurinol
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Peripheral neuropathy
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can result in kernicterus in new borns
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Sulfonamides
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give examples of the drugs used as a one dose treatment for Gonorrhea?
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O.N.E. = Ofloxacin, Norfloxacin and Enoxacin (all Fluoroquinolones used in a one dose treatment)
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drug that treats RSV (respiratory syncytial virus)
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Ribavirin
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