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45 Cards in this Set
- Front
- Back
Buzz Words for ALL
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pancytopenia, radiation therpay, down syndrome
CHILDREN |
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Buzz words for AML
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Auer Rods
DIC |
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Buzz Words for CML
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Philadelphia Chromosome
WBC >50,000 splenomegaly associated with myelodysplasia/myelofibrosis |
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Buzz Words for CLL
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males, LAD
smudge cells |
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Burkit Lymphoma
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associated with EBV
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Hodgkins Disease
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associated with Reed Sternberg Cells, cervical LAD, night sweats
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Multiple Myeloma
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Bence-Jones proteins, osteolytic lesions, high calcium level
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Steps of management with cord compression
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start high dose steroids
MRI radiation surgical decompression |
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MEN, type I
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Parathyroid
Pituitary Pancareas |
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MEN, type IIa
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Thyroid (medullary cancer), parathyroid, pheochromocytoma
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MEN, type IIb
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Thyroid (meduallry cancer), pheochromocytoma, mucosal neuromas
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Gardner Syndrome
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Familial polyposis plus osteomas and soft tissue tumors
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Turcot syndrome
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Familial polyposis plus CNS tumors
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Peutz Jeghers syndrome
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perioral freckles, non cancerous GI polyps
increased incidence of noncolon cancer; no increased risk of colon cancer |
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Neurofibromatosis Type I
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neurofibromas, cafe-au-lait spots
increased pheochromocytomas Wilms tumor leukemia |
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Neuroifibromatosis Type 2
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bilateral acoustic schwannomas
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Tuberous sclerosis
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seizures, mental retardation
inc. renal angiomyolipomas and cardiac rhabdomyomas |
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von Hippel-Lindau disease
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hemangiomas in cerebellum, renal cell cancer
cysts in liver and/or kidney |
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Consequences of lung cancer
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Horner's syndrome, diaphragm paralysis, hoarseness, superior vena cava syndrome, cushing syndrome, SIADH, hypercalcemai, Eaton-Lambert syndrome
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Biggest risk factor for breat cancer
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personal hx of breast cancer
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Conservative approach with breast cancer
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bx every palpable breat mass in women over 35 years. Women under 30, breat ca is extrmely rare
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Most common histologic type of breast cancer
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invasive ductal carcinoma
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Treatment of prostate cancer
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local --> prostatectomey
mets --> orchiectomy, leuprolide (gonadotropin releasing hormone agonist), flutamide (adrogen receptor antagonist), estrogen (diethylstilbestrol) |
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where does colon ca freq metastisize to?
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liver
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Classic presenataion of pancreatic CA
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adenocarcinoma
epigastric pain, migratory thrombophlebitis palpable, non tender gallbladder smoker, weight loss, jaundice |
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work up on insulinoma
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check C-peptide
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Mos common ovarian cancer
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serous cystadenocarcinoma
psammoma bodies on histopathology |
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Sertoli-Leydig Cell tumors
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cause virilization
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granulosa/theca cell tumors
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cause femininization
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Steps followin dysplastic Pap smear
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colposcopy-directed bx and endocervical curettage
micorinvasrive ca --> conix=zation invasive --> surgery asnd xrt |
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Post menopausal bleeding
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think endometrial cancer!!
get pap smear, endocervical curettage and endometrial bx |
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tx for endometrial cancer
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surgery and xrt
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Most common brain tumors in aduls
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gliomas
meningiomas |
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most common brain tumors in children
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cerebellar astrocytomas
medulloblastomas ependymomas |
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Evaluation of throid cancer
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be susp of cold nodules
consider FNA, US, or open bx |
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most common primary tumor of liver
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hemangiona (adults)
mepatoblastoma (children) |
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Krukenberg tumor
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stomach cancer with bilaterla mets to ovary
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Virchow's node
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left supracalvicular node enlargement due to visceral cancer spread
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classsic finding in osteosarcoma
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"sunburst" or Codman's triangle appearnace of periosteal reaction in the distal femur or proximal tibia
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S-100
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melanoma, cns/nerve tumors
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HCG
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hydatiform moles, choriocarcinoma
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AFP
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liver, testicular (yolk-sac)
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CEA
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colon, pancreas, other GI tumors
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Unicameral bone cyst
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lesion in proximal portion of humerus
children, adolescents may weaken bone to cause fracture |
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Histiocytosis
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CD-1
Birbeck granules |