Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
fluorouracil (4)
|
-stomatitis
-mucositis -diarrhea -hand and foot syndrome |
|
capecitabine (Xeloda) (3)
|
-mucositis
-diarrhea -hand and foot syndrome |
|
cytaribine (Cytosar) (2)
|
-neurotoxicity (2-3g/m2)
-conjunctivitis (corticosteroid eye drop px) |
|
gemcitabine (Gemzar) (2)
|
-myelosuppression = thrombocytopenia
-increased LFTs |
|
fludarabine monophosphate (Fludara) (2)
|
-myelosuppression
-immunosuppression |
|
methotrexate (Rheumatrex) (4)
|
-mucositis
-nephrotoxicity (NaHCO3 w/ D51/2NS 100mEq/L @ 150mL/hr starting 12hr prior to dose) -hepatotoxicity -neurotoxicity |
|
pemetrexed (Alimta) (3)
|
-skin rash (dexamethasone 4mg BID x3days, day prior to dose)
-fatigue -myelosuppression (give folic acid and vitamin B12-avoid NSAIDs and aspirin) |
|
vinblastine (Velban) (2)
|
-myelosuppression
-extravasation |
|
vincristine (Oncovin) (3)
|
-neurotoxicity
-constipation -extravasation |
|
vinorelbine (Navelbine) (2)
|
-myelosuppression
-extravasation |
|
paclitaxel (Taxol) and docetaxel (Taxotere) (3)
|
-hypersensitivity (creamofor-tylenol, benadryl, pepcid, corticosteroids for px)
-peripheral neuropathy -fluid retention (>w/docetaxel) |
|
irinotecan (Camptosar) (2)
|
-diarrhea (acute=atropine; chronic=loperamide)
-mucositis |
|
doxorubicin (Adriamycin), daunorubicin (Daunomycin), and idarubicin (Idamycin) (4)
|
-extravasation
-red secretions -secondary leukemias -cardiotoxicity (dexrazoxane) |
|
mitoxantrone (Novantrone) (2)
|
-blue/green secretions
-extravasation |
|
cyclophosphamide (Cytoxan) and ifosfamide (Ifex) (2)
|
-neurotoxicity (Ifex)
-hemorrhagic cystitis (2ndary to acrolein-give MESNA always for Ifex-give b4 and at 4 and 8hrs following dose, in doses 60-100% ifosfamide dose) |
|
carmustine (BICNU) and lomustine (CCNU) (1)
|
-delayed myelosuppression up to 28-30days following chemotherapy
|
|
cisplatin (Platinol) (4)
|
-nephrotoxicity (IVFs and electrolyte replacement, amifostine)
-nausea and vomiting -ototoxicity -neuropathy |
|
oxaloplatin (Eloxatin) (2)
|
-neurotoxicity (laryngopharyngeal spasms exacerbated by cold)
-neuropathy |
|
trastuzumab (2)
|
-infusion rxns
-cardiomyopathy |
|
rituximab (1)
|
-infusion rxns (premedicate w/ APAP and benadryl)
|
|
gemtuzamab (2)
|
-hepatic dysfunction
-myelosuppression |
|
cetuximab (2)
|
-acneform rash
-infusion rxns |
|
alemtuzumab (2)
|
-immunosuppression
-infusion rxns |
|
bevacizumab (1)
|
-thromboembolic events
|