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49 Cards in this Set
- Front
- Back
- 3rd side (hint)
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alpha fetoprotein
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liver
testicular (yolk-sac) |
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bladder tumor antigen
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bladder
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NMP 22
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bladder
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CA 15-3
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breast
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CA 27.29
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breast
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CA 19-9
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pancreas
lung breast |
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CA-125
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ovarian
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carcinoembryonic antigen (CEA)
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colon, pancreas, other GI
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chromogranin A
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carcinoid tumors
neuroblastoma |
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HCG
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hydatiform moles
choriocarcinoma |
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beta2-microglobulin
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multiple myeloma
CLL |
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PSA
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prostate
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S-100
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melanoma
CNS tumors nerve tumors |
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thyroglobulin
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thyroid
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ALL
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pancytopenia
Hx of radiation therapy Down's |
3-5 yo
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AML
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pancytopenia
Auer rods DIC |
>30 yo
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CLL
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males
lymphadenopathy lymphocytosis infections smudge cells splenomegaly |
>50 yo
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CML
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WBC >50,000
Phil. chromosome blast crisis splenomegaly |
30-50 yo
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Hairy cell leukemia
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hairlike projections on blood smear
splenomegaly |
adults
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mycosis fungoides, sezary syndrome
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plaque-like itchy skin rash that does not improve
blood smear shows cerebriform nuclei pautrier abcesses in epidermis |
>50 yo
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burkitt's lymphoma
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Associated with EBV in africa
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children
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CNS B-cell lymphoma
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HIV/AIDs
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adults
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T-cell leukemia
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can be caused by HTLV-1
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adults
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Hodgkins dz
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Reed-Sternberg cells
cervical lymphadenopathy night sweats |
15-34 yo
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non-hodgkins lymphoma
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best px - small follicular
poor px - large diffuse primary tumor can be in GI tract |
any age
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myelodysplasia, myelofibrosis
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anemia
tear-drop cells dry tap on bone marrow bx high MCV and RCDWI associated with CML |
>50 yo
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multiple myeloma
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bence jones protein
osteolytic lesions high calcium |
>40 yo
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Waldenstrom's dz
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hyperviscosity
IgM spike cold agglutins |
>40 yo
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Polycythemiavera
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high Hb
pruritis after hot shower tx phlebotomy |
>40 yo
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primary thrombocythemia
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Plt >1,000,000
bleeding or thrombosis |
>50 yo
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What are the 3 most common cancers in women?
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breast, lung, colon
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What are the 3 cancers with the highest mortality in women?
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lung, breast, colon
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What are the 3 most common cancers in men?
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prostate, lung, colon
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What are the 3 cancers with the highest mortality in men?
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lung, prostate, colon
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Retinoblastoma
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AD
--> osteogenic sarcoma later in life |
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MEN type I
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AD
--> parathyroid, pituitary, pancreas (islet cell) one = 3 Ps |
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MEN type IIA
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AD
--> thyroid (medullary), parathyroid, pheo |
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MEN type IIB
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AD
--> thyroid (medullary), mucosal neuromas, pheo both type twos have thyroid and pheos. A also has parathyroid (A and I). B also has weird mucosal crap, hence it's b grade. |
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Familial polyposis
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AD
--> colon polyps. duh. |
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Gardner's syndrome
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AD
--> familial polyposis + osteomas, soft tissue tumors |
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Turcot's syndrome
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AD
--> familial polyposis + CNS tumors |
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Peutz-Jeghers syndrome
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AD
--> perioral freckles (..odd,) non-cancerous GI polyps, increased risk of stomach, breast, ovarian cancers. |
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Neurofibromatosis I
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AD
--> neurofibromas + cafe-au-lait spots, pheos, bone cysts, Wilms' tumor, leukemia |
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Neurofibromatosis II
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AD
--> bilateral acoustic schwannomas |
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Tuberous sclerosis
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AD
--> adenoma sebaceum, seizures, MR, glial nodules, renal angiomyolipomas, cardiac rhabdomyomas |
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Van Hippel-Lindau dz
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AD
--> hemangiomas in cerebellum, renal cell cancer, cysts in liver/kidney |
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Xeroderma pigmentosum
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AR
--> skin cancer |
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Albinism
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AR
--> skin cancer why did i type this one |
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Down's syndrome
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--> leukemia
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