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6 Cards in this Set

  • Front
  • Back
Testicular cancer: unimodal or bimodal distribution?
Bimodal.

There's a second peak after age 60
Associations / risk factors for testicular cancer?
Prior testicular cancer (500x)

Cryptorchidism (20-40x)

Isochromosome 12p

Klinefelter's / Marfan's Syndrome

BONUS:
There are NOT associations or risks -- trauma, elevated scrotal temperature, horseback riding
Testicular cancers histology?
Majority are germ cell, of which there are seminomas and non-seminomas

BONUS:
non-germ cell: Leydig, Sertoli
Can testicular cancer present with gynecomastia?
Yes.

Beta-hcg can cause gynecomastia
Treatment of seminomatous testicular cancer?
XRT

(preceded by orchiectomy)
(and unless there's disseminated disease that's it)
Seminomas are exquisitely sensitive
Treatment of non-seminomatous testicular cancer?
Retroperitoneal lymph node dissection +/- Chemo

(preceded by orchiectomy)