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6 Cards in this Set
- Front
- Back
Testicular cancer: unimodal or bimodal distribution?
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Bimodal.
There's a second peak after age 60 |
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Associations / risk factors for testicular cancer?
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Prior testicular cancer (500x)
Cryptorchidism (20-40x) Isochromosome 12p Klinefelter's / Marfan's Syndrome BONUS: There are NOT associations or risks -- trauma, elevated scrotal temperature, horseback riding |
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Testicular cancers histology?
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Majority are germ cell, of which there are seminomas and non-seminomas
BONUS: non-germ cell: Leydig, Sertoli |
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Can testicular cancer present with gynecomastia?
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Yes.
Beta-hcg can cause gynecomastia |
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Treatment of seminomatous testicular cancer?
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XRT
(preceded by orchiectomy) (and unless there's disseminated disease that's it) Seminomas are exquisitely sensitive |
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Treatment of non-seminomatous testicular cancer?
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Retroperitoneal lymph node dissection +/- Chemo
(preceded by orchiectomy) |