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20 Cards in this Set
- Front
- Back
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abl
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CML
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c-myc
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Burkitt's lymphoma
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bcl-2
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inhibits apoptosis, so gain of function --> growth (less apoptosis)
follicular & undifferentiated lymphomas |
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erb-B2
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breast, ovarian, & gastric carcinomas
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ras
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colon carcinoma
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L-myc
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lung tumor
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N-myc
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Neuroblastoma
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ret
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MEN II & III
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c-kit
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GIST (gastrointestinal stromal tumor - lots of spindle cells)
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Rb
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13q retinoblastoma, osteosarcoma
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BRCA1
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17q; breast & ovarian CA
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BRCA2
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13q; breast CA
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p53
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17p; most CAs + Li-Fraumeni syndrome
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p16
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9p; melanoma
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APC
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5q; colorectal CA
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WT1
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11p; Wilm's tumor (nephroblastoma)
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NF1
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17q; NF type 1
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NF2
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22q; NF type 2
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DPC
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18q; pancreatic CA
(stands for deleted in pancreatic CA) |
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DCC
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18q; colon CA
(stands for deleted in colon CA) |
