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91 Cards in this Set

  • Front
  • Back

Neoplasm

Tumor

Vesicant

Chemo drugs that is known to be irritating

Carcinogens

Factor or agents that appear to cause cancer

Extravasation

Leakage of IV medications into the tissues surrounding the IV site

Alcohol

Causes liver cancer and liver cirrhosis

Smoking/ Tobacco

Causes:


Lung CA


Bladder CA


Cervical CA

Asbestos

Very adhesive and sticky



Causes Lung CA

What is true in ONCO?

THERE ARE NO EXACT CAUSE!

Pap Smear for Cervical CA

@ 21 y/o



Every 3 years if normal



Every 1 year if abnormal

Grading

Checking for CA cells


Kung kumalat ba or hindi


Well or poor differentiation

Staging

Checking for tumor, nodes, metastatasis

Ann Arber

Use for Hodgkin's and Non-hogkin's Disease

HWBE

Health Worker Breast Examination



Every 3 years for age 20-39


Every 1 year for age 40 and above

Biopsy aka

1. Excisional


2. Incisional


3. Fine needle aspiration


4. Microscopic analysis

Use of needle

Aspiration

Tissue samples is removed

Incision

Whole mass is removed


Curative diagnosis


For superficial only

Excision

Electric current to destroy tumor

Electrosurgery

Liquid nitrogen is used to freeze tissue to cause cell destruction

Cryosurgery

Topical chemotherapy and surgical removal of mass

Chemosurgery

Radiation Therapy

Reduce the size of the tumor but it can kill cancer cells

Most common SE of Radiation Therapy

Fatigue

External Radiation

Client is not radioactive (does not emit radiation)



Done in outpatient


15-30 mins per session


2-5 days a week


2-7 weeks (whole treatment)

SE of External Radiation

Radiodermatitis or Radiation Burns



Mngt:


Cornstarch


Calamine lotion (OFF lotions)


Steroids

Internal Radiation

Client is radioactive during and after procedure

Interstitial site

Directly placed at the tumor

Intercavity site

Placed in a cavity/orifice

HDR

High Dose Radiation


No need hospitalization



10-20 mins, 2x a day, for 2-5 days

LDR

Low Dose Radiation


Needs hospitalization



CONTINUOUS for 2-7 days

Time

30 mins per shift


5 minutes per visit


6 visits in total

Distance

3-6 feet

Sealed Brachytherapy Mngt

Void/defecate before procedure


CBR


Low fiber


Urinary catheter

Unsealed Brachytherapy

2-3 flush after use


Ambulatory


FORCE FLUIDS!

Chemotherapy

Slows or delays growth



Lacks specificity (can attack normal cells)

Nadir

Too low PLT (< 74K)


occur on the 8th day of chemo

Anti-metabolites

Blocks DNA synthesis (S phase)

Examples of Anti-metabolites

1. Flouracil


2. Methotrexate


Toxicity:


Vomiting


Abdominal Cramping


Nausea


Stomatitis (mngt: Hydrogen peroxide)


Antidote: Leucovorin (Wellcovin)



3. Mercaptoprine


PO


Maintenance for ALL


30 mins to 1 hour after giving milk or dairy products


Mitotic Inhibitors/ Vinca Alkaloids/ Plants Alkaloids

Blocks mitosis (M phase)

Examples of Mitotic Inhibitors

1. Vincristine (Oncovin)


-bone marrow friendly


-SE: neuropathy or nerve damage


- paresthesia (numbness or tingling)



2. Vinblastine (Velban)

Most common SE of Chemo

N and V

Diet of pt im Chemo

Increase fluid intake (prone to DHN because of vomiting and diarrhea)



Low fiber (due to diarrhea)



High protein and high calorie

Pancreatic Cancer Surgery

Whipple Procedure / Pancreaticodoudenectomy



Removal of gallbladder, common bile duct, part of duodenum and head of pancreas

Cholecystectomy: Position and DOC

Removal of gall bladder



Low-fowler's position



Morphine

T tube care

1. Maintains patent bile duct


2. Report sudden increase of drainage


3. Clamp tube before meals


4. Unclamp if N/V develops

Colon Cancer

Equally occuring in men and women



(>50 y/o) think of "COLON"

Clinical Manifestation of Colorectal Cancer

Most common: Changes in bowel habits



2nd common: Hematochezia



Pencil-like stools

Diagnosis of Colorectal Cancer

DRE: Annually (>40 y/o)



Occult Stool Exam: Annually (>50 y/o)



Carcinoembryonic antigen (CEA)

Pre-op for Colorectal Cancer

1. Bowel cleansing


2. Low residue 3-5 days before


3. Laxative and cleansing enema


4. Pre-op antibiotic: NEOMYCIN TABLET

Post-op Colorectal Cancer

1. Flatus and fecal drainage: 4-7 days


2. Use KARAYA paste on skin barrier; TALC/CORNSTARCH


3. NEVER USE MINERAL OIL


4. Use statin powder for Candida Albicans

Skin Cancer leading cause

Exposure to the sun

Basal Cell Carcinoma

Most common type


Rarely metastasize


Good prognosis

Squamous Cell Carcinoma

Can metastasize

Malignant Melanoma

Deadliest


3rd most common type


Arise from birthmarks or moles in any place

Most nutrients are absorbed

Jejenostomy

Carcinogen: overcooked food

Benzopyrene

Carcinogen: preservatives

Nitrosamine

Carcinogen: Peanut/ Peanut butter

Afflatoxin

Lung Cancer: Risk factor

Radon


- odorless, colorless chemical


- usually found in soil (miners, etc.)

Lobectomy

One lobe removal

Pneumonectomy and post-op

Removal of entire lung



Post-op


GOAL: positive pressure in the affected side


1. CTT is contraindicated - to avoid tracheal deviation


2. Position on affected side!

Total laryngectomy: What is permanent?

Tracheostomy

Peritonitis s/sx

Fever


Board like abd


Dull on percussion

Bladder Cancer: Most obvious sign

Painless hematuria

Bladder Cancer Surgery

CYSTECTOMY - Removal of bladder



PARA KANG MANOK!



1. Ileal conduit - ureters to ileum


2. Colon conduit - ureters to colon

Multiple Myeloma/ "KOHLER" DISEASE

Cancer of the plasma (function: Production of IG)



60 y/o and above: Think of "KOHLER"

Manifestation of Kohler Disease

1. Low RBC, WBC, PLT


2. Hyperuricemia


3. Hypercalcemia


4. Brittle Bone (pathological fractures)


5. U/A - presence of Bence Jones Protein

Hodgkin's Disease

Cancer of the LN



With REED STERN - BERG CELLS (Owl's Eye)


Better prognosis



Bimodal Age: 15-30 to 40 y/o and then more than 50 y/o



EPSTEIN BARR VIRUS (Kissing Disease)

Non-hogkin's Disease

Without RSB



Poor prognosis



Burkitt' s Lymphoma (common in India)


HIV


Age 60 y/o and above

Presenting Sign of Hodgkin's Disease

Painless swelling of lympnodes

Early manifestation of Hodgkin's Disease

B-symptoms


1. Persistent fever


2. Night sweats


3. Weight loss (10% of BMI)




Note: A-symptoms if one of the 3 is missing

Cervical Cancer Risk factors

HPV


Multiple sex partners


Early intercourse (16 y/o and below)

Breast Cancer Risk Factors

Late menopause (55 y/o and above)


Obesity


Nulliparity


Genetics


Female, Forty, Fat diet


Oral contraceptives


Early menarche (11 y/o and below)

Breast Cancer Characteristics

Often firm (made of cancer cells)


Immovable; immobile


Irregular margins


No pain and tenderness


Unilateral

Affected breast?

Left


Upper outer quadrant (near tail of spens)

Specific place where tumor grows

Milk lobules

Mammography

Low dose xray of the breast used to detect tumors before they can be felt



Start at 40 y/o annually



Baseline mammogram at 35-39 y/o

Mammogram: white?

Tumor



Black: Fats

Lumpectomy

Lump only

Simple/ Total mastectomy

Whole breast

Quadrantectomy

Per quadrant only

Radical Mastectomy aka

Halstead Procedure with skin graft

Halstead Procedure with skin graft

Whole breast


LN


Pectoralis major and minor muscles

MRM

Pectoralis minor is not removed



Can be used as pocket for breast implants

Prostate Cancer Risk Factors

This is SLOW GROWING



STD


Testosterone


African American


Forty (40 y/o) and Above


Fat diet

Early Sign of Prostate Cancer

Asymptomatic @ early stage

Presenting sign of Prostate Cancer

Enlargement of prostate

Late sign of Prostate Cancer

Low back pain (pelvic bone)

Diagnostic Test for Prostate Cancer

Prostate Specific Antigen (PSA)


Or aka Total Specific Antigen


- cancer marker


- CHON produced by the prostate gland

Normal PSA

0.2 to 4 nanogram/ ml



Prostate Cancer


- 8 above (suspected only)


- sides (prostate)



BPH


- 5 to 7


- center (prostate)

Testicular Cancer Risk Factors

Cryptorchidism


Age: 15-35 y/o


Trauma



Diethylstilbestrol (DES)


Orchitis


Genetics

Testicular Cancer Surgical Mngt

Orchiectomy