Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/16

Click to flip

16 Cards in this Set

  • Front
  • Back
small lymphocytic lymphoma - No germinal centers, no sinuses – just a sheet
a
small lymphocytic lymphoma - No germinal centers, no sinuses – just a sheet
a
Small lymphocytes
a
Intermediate/mantle cell
lymphocytes
a
Small Cleaved lymphocytes
a
Diffuse Large B-Cell Lymphoma - Intermediate Grade
a
Lymphoblastic Lymphoma - High Grade
a
Lymphoblastic Lymphoma - High Grade
a
Burkitt’s Lymphoma - High Grade - Macrophages with debris form the “starry sky
a
Burkitt’s Lymphoma - involving the bone marrow - Characteristic cytoplasmic
vacuoles
a
small lymphocytic lymphoma (SLL)
- low grade but not curable
- disease of the elderly
- like CLL but in lymph
- Mature B-cell - (CD19-23) co-expressing CD5, & κ or λ
follicular (small cleaved cell) lymphoma
- low grade but incurable
- t(14;18) -> too much Bcl2
- Age and HIV determine - 2nd most common lymphoma
- Mature B-cell (CD19, 20, 22) w/ CD10+ and κ or λ
Large Diffuse Cell Lymphoma
- intermediate grade but curable w/ RCHOP + Rituximab
- Most common type of NHL
- Can have B symptoms
- BCL6 (3q26-27) is common, but is better prognosis
- Transformation of germinal center centroblasts
- 1/3 extranodal - GI, brain
Lymphoblastic Lymphoma
- high grade
- Young, usually female
- Ass. w/ mediastinal mass
- Treated like ALL
- T-cell w/ CD3, 4, 8 and TdT
Burkitt’s lymphoma
- agressive - can get Tumor lysis syndrome -> renal probs
- abdominal mass - no EBV in US, but EBV in africa
- Ass. w/ t(8;14) -> c-myc
- like L3 ALL, w/ Mature B-cell phenotype
chromosomes usually involved w/ lymphoma
- 14 (Ig heavy chain)
- 2 (k light chain)
- 22 (l light chain)