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27 Cards in this Set
- Front
- Back
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What is the mildest MR?
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chlorzoxozone
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What drug blocks desc reticular formation and SC?
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carisoprodol
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What is the metabolite of carisoprodol?
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meprobromate (class IV anxiolytic)
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What is in SOMA cmpd?
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carisoprodol + Asa
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Carisoprodol causes what SE?
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idiosyncratic rxn - tsient quadriplegia, loss of vision, dysarthria, disorientation, agitation
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What are the SE of methocarbamol?
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dizziness, light headedness, nausea
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What are the 3 mid range strength MR?
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carisoprodol, methocarbamol, orphenadrine citrate
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What is robaxisal?
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methocarbamol + Asa
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What are 2 effects of orphenadrine citrate?
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analgesic, anticholinergic
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What are SE of orphenadrine citrate?
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dizziness, drowsiness, dry mouth
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What is in norgesic?
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orphenadrine citrate + Asa + caffeine
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What strength is metaxalone?
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strong
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What are SE of metaxalone?
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N/V, drowsiness, dizziness, HA, nervousness
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What is strongest MR?
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cyclobenzaprine
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What is warning w/ cyclobenzaprine?
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do not combine w/ MAOIs or TCAs
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What are the indications of diazepam?
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acute m spasm, spasticity of UMN dz, Stiffman syn
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What is warning w/ diazepam?
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drug abuse potential
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What are SE of diazepam?
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confusion, constipation, depression, diplopia, dysarthria, drowsiness, ataxia
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What is indication for baclofen?
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chronic spasticity states
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What is MOA of baclofen?
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inhibits monosynaptic and polysynaptic reflexes at spinal level
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What is warning w/ baclofen?
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abrupt w/d may lead to rebound spasticity, hallucinatin, seizures
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What is indication of dantrolene sodium?
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antispasticity drug of last resort
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What is MOA of dantrolene sodium?
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inhibits activity of myoneural junction
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What is warning of dantrolene sodium?
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potential for fatal hepatotoxicity
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What are indications for pregabalin?
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diabetic peripheral neuropathy, post herpetic neuralgia, partial onset of seizures, fibromyalgia
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What is MOA of pregabalin?
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binds alpha 2 site on Ca++ channelin CNS (but does not block channels), inc GABA tport, dec Ca++ dependent release of NT
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What are warnings for pregabalin?
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angioedema, hypersensitivity, inc seizure freq, peripheral edema, dizziness
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