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10 Cards in this Set
- Front
- Back
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Conventional Ameloblastoma
Histology? |
* Mixed cystic and solid areas
* Infiltrative * Nests and sheets of cells, surrounded by mature fibrous tissue * Peripheral cells of nests are columnar with nuclei polarized away from basement membrane * Reminiscent of enamel organ epithelium * Histo pattern does not affect treatment or prognosis |
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Unicystic ameloblastoma
Histology? |
Luminal: Fibrous wall with cystic epithelial lining
* Cyst lining with focal areas of basal cell nuclei polarized away from basement membrane and with a stellate reticulum * Not infiltrative into fibrous wall Intraluminal (plexiform): Nodules of ameloblastoma project into the lumen * Appears to have interconnecting (plexiform) pattern * Not infiltrative into surrounding fibrous wall Mural: Ameloblastoma infiltrates the surrounding fibrous wall |
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Peripheral ameloblastoma
Histology? |
* Same appearance as central ameloblastomas
* May be continuous with surface epithelium * By definition, should not infiltrate into bone. If it does, it may be a central ameloblastoma that has eroded through the cortex |
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Ameloblastic carcinoma
Histology? |
Cytologic features of malignancy in the primary tumor, recurrence, or metastasis.
Characterized by: increased nuclear/cytoplasmic ration, hyperchromatism, mitoses |
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Adenomatoid Odontogenic Tumor (AOT)
Histology? |
* Well-circumscribed
* Spindle-shaped epithelial cells in sheets or whorled masses * Rosette areas filled with amyloid * Tubular or duct-like structures are characteristic * Mineralized material may look like enamel, dentin, or cementum |
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Calcifying Epithelial Odontogenic Tumor (CEOT)
aka Pindborg Tumor Histology? |
* Islands, strands, and sheets of polyhedral epithelial cells
* Nuclei may show prominent pleomorphism * Large areas of hyalinized, eosinic material (amyloid) * In the amyloid material, get distinctive calcifications with concentric rings (Liesegang) |
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Ameloblastic Fibroma
Histology? |
* Well-circumscribed lesion
* Usually solid tumor * Cords and strands of odontogenic epithelium * Surrounded by loose, mesenchyme-like connective tissue with plump fibroblasts |
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Ameloblastic Fibro-odontoma
Histology? |
* Same soft tissue components as ameloblastic fibroma
* In conjunction with a complex odontoma * Rarely, no enamel is seen, so it is then called an ameloblastic fibro-dentinoma |
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Central Odontogenic Fibroma
Histology? |
* Variable loose and dense fibrous tissue
* May be focal calcification * Some cases have islands and cords of odontogenic epithelium (these are called the WHO type) |
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Odontogenic Myxoma
Histology? |
* Often erodes through cortical bone and infiltrates in connective tissue
* Gelatinous, loose, myxoid connective tissue with fibroblasts ("ground substance") * Resembles mesenchyme of dental pulp * May occasionally see odontogenic epithelial islands |
