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36 Cards in this Set

  • Front
  • Back
Drugs that cause Whorl Keratopathy?
"CHAI Tea"
Chloroquine
Hydroxychloroquiine
Amiodarone
Indomethacin
Tamoxifen
What ocular side effects are caused by accutane?
1. SPK
2. Dry Eyes (and lid edema)
3. Color vision loss
4. Nyctalopia
5. Pseudotumor cerebri
What drug can cause pigment deposits on Desc and Endo?
Chlorpormazine (schizo/bipolar)
What can cause corneal melting?
Topical NSAIDS
- including benoxinate in fluoress
What are the 3 ocular side effects of Amiodarone?
1. Whorl Keratopathy
2. Ant subcap cat
3. NAION
What DISEASE can lead to Whorl Keratopathy?
FABRY disease = lysosomal storage disease that can also cause spoke-like lens opactities
Ocular Side effects of Chlorpromazine?
1. Pig on corneal endo
2. Ant Subcap Cat
3. Mydriasis
4. Dry Eyes
5. Increase IOP

(drug for Schizo)
What drugs can cause Anterior Subcapsular Cataracts?
1. Amiodarone
2. Chloropromazine
3. Miotics
What ethnicity is at greatest risk of PSC from corticosteroids?
Hispanics
What class of drugs can lead to Stevens Johnson Syndrome and lid edema?
Sulfonamides

(rare though!)
What drugs can lead to subconjunctival hem?
NSAIDS

Viagra
What class of drugs can cause pigmented cysts on conjunctiva?
Tetracyclines
Drugs that can cause dry eyes:
1. Antihistamines
2. Anticholinergics (atropine, scopolamine)
3. Antidepressants
4. B blockers
5. Hormones
6. Accutane
7. Phenotiazines
8. CNS stimulants (Ritalin, Dexedrine)
9. Diuretics (Hydrochlorothiazide)
What drugs can cause Mydriasis?
1. Antihistamines (Benedryl)
2. CNS stimulants (Ritalin, Dexedrine, Cocaine)
3. CNS depressants
4. Anticholinergics (Atropine, Scopolamine)
5. Phenothiazines
Drugs that can cause miosis?
1. Opiates (morphine, heroine, codeine)
2. Anticholinesterases (neostigmine)
If somtone is exposed to nerve gas or insecticides, they may have miosis that lasts for a month! What drug can be used to reverse this effect?
Pralidoxamine

(give praline to gardener)

Nerve gas and insectisides have anticholinesterase agents
What drugs can cause nystagmus?
1. Phenytoin (Dilantin)
2. Phenobarbital (Luminal)
3. NSAIDS
What drugs can cause Diplopia?
Anti-depresssants and anti-anxiety
What does alcohol cause in the eyes?
Smooth pursuits
What is Oculogyric crisis?

What drugs can cause it?
when EOMs spaze out, leaves the eye usually elevated

caused by Phenothiazines and Zyrtec !
What drug can cause floopy iris syndrome?
Flomax
What drugs can lead to uveitis?
1. Cidofovir (oral for CMV)
2. Rifabutin (TB)
3. Sulfonamides
What drugs and disease can cause BLUE Sclera?
Drugs:
Corticosteroids and Minocycline

Diseases:
Osteogensis Imperfecta and Ehlers Danlos
What drugs can cause retrobulbar optic neuritis?
Digoxin (heart disease)
Ethambutol and Isoniazid (TB)
What 3 drugs can cause NAION?
1. Viagra
2. Sumatriptan (migraines)
3. Amiodarone
What effects can oral contraceptives have on the optic nerve?
optic neuritis, papilledema, pseudotumor cerebri

rare !
What drug can cause Bull's Eye Maculopathy
Chloroquine = Plaquenil
What drug can cause CME>
topical Epinephrine
What drug can leave crystal depostis, esp around macula?
Tamoxifen
What drug causes pigmentary retinopathy?
Thioridazine (anti-psychotic)
What drug can cause color vision loss and nyctalopia?
ACCUTANE
what drugs can lead to retinal hem?
NSAIDS

Birth control
What drugs can cause pseudotumor cerebri?
1. Accutane
2. Tetracyclines (minocyclin and doxycycline)
What drugs can decrease IOP as a side effect?
1. Digoxin
2. Beta blockers
3. Alcohol
4. pot
What drugs can increase IOP?
1. Atropine and Scopolamine
2. Anithistamines
3. TCAs
4. Anitpsychotics (phenothiazines)
Explain how corticosteroids can increase IOP?
Decrease aq outflow
- decreased ability for TM cells to replace matrix and phagocytose debris
- thickening of TM fibers and juxtacanalicular tissue