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8 Cards in this Set

  • Front
  • Back

When the eye is involved in thyroid disease?

Dysthyroid ophthalmopathy.

When eye signs of Graves disease occur in a patient who is not clinically Hyperthyroid is termed?

Ophthalmic Graves disease.


Occurs in 10-25%

Pathogenesis of dysthyroid opthalmopathy?

IGG antibodies cause


1. Hypertrophy of extraocular muscles due to increase in glycosaminoglycan.



2. Infiltration of the interstitial tissues with chronic inflammatory cells leading to fibrosis.



3. Proliferation of orbital fat, connective tissue and lacrimal gland.

List the clinical manifestation of Dysthyroid opthalmopathy

1. Eye retraction


2. Soft tissue involvement


3. Proptosis


4. Optic neuropathy


5. Restrictive myopathy.

Dalrymple sign

Upper eyelid retraction in primary gaze.

Vongraefe sign

Upper lid lig on down gaze..

Kocher 's sign

Staring and frightened appearance of eyes.

Werners classification of Graves ophthalmopathy.

NO SPECS


0. No ocular signs and symptoms


1. Only signs eye retraction with or without lid lag and mild proptosis. No symptoms


2. Soft tissue involvement


3. Proptosis


4. Extraocular muscles involvement


5.Corneal involvement


6. Sight loss following optic nerve involvement.