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14 Cards in this Set

  • Front
  • Back
The 3 parts of the htin filaments?
Actin, Troponin, Propomyocin
A bands?
overlapping actine and myocin
I bands?
actin alone
5 steps of the cross bridge cycle?
1. Energized cross bridges
2. Pi is released and cross bridge rotates "power stroke"
3. ATP binds myocin head; cross bridge detaches
4. Hydrolysis of ATP on myocin head energized cross bridge
How does tropomyocin regulate contration?
Ca+ binds to troponin and canses a conformation change in troponomyocin which exposes the inding sites actin
2 Ca+ binding protiens in the lateral sacs?
calseqestin, calcreticulin
Isometric contraction?
non change in muscle length
Isotonic contraction?
There is a change in kuscle length
Optimal length?
produces maximal tension
3 characteristics of different muscle types?
myosic ATPase activity. (fast or slow twitch)
metabolism (oxidative or glycolytic)
Fiber size (big small)
A propposed mechanism for fatigue?
accumulation of PO4 during muscle activity that inhibits cross bridge binding to actin
Shift in fiber type?
Fast twitch muscles can change thier metabolism class
fascicles?
bundules of muscle fibers
How is Ca+ released into the SR?
It is released from L-type Ca+ channels then go through Ryandine receptors into the SR.