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43 Cards in this Set
- Front
- Back
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Rickettsia vs. Chlamydia
making atp |
chlamydia cannot make its own APT - rickettsia can
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how does rickettsia multiply
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slowly by binary fission w/in vacuole of endothelial cells
causes lysis of cell |
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causes typhus
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rickettsia prowazekii
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treatment of typhus
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tetracycline
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vector of r. prawazekii
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louse -
louse defecates |
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symptoms of typhus
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fever, headache, rash
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diagnosis of typhus
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increase in ab serological tests
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Weil-Felix reaction
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old serological test used to test for r. prowazekii. based on cross-reacting Ag - not used cause even though it is sensitive - it is not specific enough
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sporadic human infections of r. prwazekii come from
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flying squirrel fleas
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Brill-Zinsser disease
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recrudescen disease of typhuus. happens when pt is immunocompressed - headache rash
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chlymidia AND rickettsia are treated with
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tetracycline
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endemic murine typhus is spread by what vector
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group squirrel flea - but rat is natural host
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rocky mountain fever vector and organism
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tick - rickettsia rickettsia
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diagnosis of rickettsia rickettsia
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fluorescent Ab on skin biopsy
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characterisitic symptome of rocky mountain spotty fever
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rash on hands and feet
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rickettsia akari cause
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rickethial pox
vector is mouse mite |
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rickettsa where outbreaks are usually confined to single building
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rickettsia akari
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cause of Q fever
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coxiella burneti
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where does coxiella burnetti come from
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no arthropod transmissoin
comes from inhalation of c. burnetti in spore like stage form placental tissue of animal |
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c. burnetti causes
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interstitial pneumonia
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ehrlichia causes what two things
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moncytic ehrlichiosis and granulocytic erlichiosis
caused by two diff obligate intracellular bacteria |
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erlichiosis cause what symptoms
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fever, lymphocytopenia
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small non-multiplying riid form of chlamydia needed for transmission
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elementary bodies
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actively multiplying form of chlamydia - non infectious
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initial bodies
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how are elementary bodies taken up into cells
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induce phagocytosis
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chlamydia cause intense inflammatory response which turns on cellular genes for the secretion of what
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lymphokines - counter intuitive
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people inhale bird feces
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chlamydia psittaci
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causes interstitial pneumonia and a natural parasite of birds
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c. psittacie
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diagnosis of c. psittaci
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1. compare acute and convalescent Ab titers
2. PCR 3. Ab to detect cytoplasmic inclusion bodies |
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can you grow c. psittaci in blood agar
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no
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c. pneumoniae is spread
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person to person
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three TYPEs of diseases caused by chlamydia trachomatis
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1. venereal
2. inclusion conjuntivitis 3. trachoma |
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may cause sterility or ectopic pregnancy, but often asymptomatic in females
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c. trachomatis
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cause of NGU
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c. trachomatis
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usually a neonatal disease passed by verticla transmission but can be STD
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inclusion conjunctivitis
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treatemtn of c. trachomatis
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azithromyzin sometimes tetracycline
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major cause of blindess world wide
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trachoma - spread via fly usually
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how might you detect prior or current disease of c. trachomatis
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DTH to heat killd LGV infected intradermally (Frei test)
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diagnosis of c. trachomatis
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PCR
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the two types of chlamydia that cause pneumonia
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c. psittici and penumoniae
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lymphoneria granomia
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caused by c. trachomasis -
STD |
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causes ulcerating papule on external genetalial - painless - rare - more invasive than other STD
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Lympnoneria granomia
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lymphoneria granomia is treated with
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tetrocycline and azithromycin
diagnosis by frei test |
