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11 Cards in this Set
- Front
- Back
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Depressive subtype~ melancholic features
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- MDE of MDD/BP
- complete loss pleasure/lack of reactivity to pleasure - worse in morning, specific mood quality, decrease psychomotor, increased weight/guilty |
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Depressive subtype~ atypical features
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MDE of MDD/BP/dysthmic
- still do things but lack pleasure - increased sleep/eat - interpersonal rejection sensitivity - may respond to MAOI |
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Depressive subtype~ catatonic features
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MDE of MDD/BP/manic/mixed
- catelepsy, purposeless activities, very negative, pecular movements - responds to ECT |
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Depressive subtype~ psychotic features
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MDE of manic/mixed
- mood cognruent/ incongruent |
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Depressive subtype~ post partum
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- MDE of manic/mixed
- DSM says up to 4 weeks after, clinically up to 6 months |
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Depressive subtype~ rapid cycling
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Has to be BP with 4 cycles within one year
- usually female - Lithium is not effective |
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Depressive subtype~ seasonal pattern
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MDE of MDD/BP
- MDE at specific time of year that recovers, pattern over 2 years |
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Serotonin (5HT) and mood disorders
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- Location~ median/dorsal raphe n (pons)
- Suicidal patients show decreased serotonin in CSF and on platelets - treat via SSRIs |
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Dopamine (DA) and mood disorders
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- ventral tegmentum
- decreased DA in depression, increased in mania - Parkinsons and depression |
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Norepinephrine (NE) and mood disorders
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- locus ceruleus
- TCAs modulate NE/serotonin |
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3 regions of the brain associated with mood disorders
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1. dorsolateral prefrontal cortex (concentration, interests, pleasure, motor fatigue racing thoughts, decreased activity in depression)
2. ventromedial prefrontal cortex (increased in depression) 3. orbito-frontal cortex (general mood) |
