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31 Cards in this Set

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  • Back
Define abortion
Expulsion of the fetus before viability, which is 20 weeks gestation or weight of less than 500g.

Types of abortions: 1. spontaneous/miscarriage (natural) or 2. induced
What is the major cause of bleeding and abortion during the first and second trimesters of pregnancy?
Abortion
First trimester period?
0 - 12 weeks (0 - 3 and a half months)
Second trimester period?
12 - 28 weeks (3 1/2 months to 6 months)
What is an ectopic pregnancy?
An ectopic pregnancy, or eccysis, is a complication of pregnancy in which the embryo implants outside the uterine cavity.
What are signs of an ectopic pregnancy and when does it occur?
Lower abdominal pain in the first trimester (0-12 wks)
4 maternal risks of HIV in pregnancy?
1. HSV (Herpes Simplex Virus)
2. Wasting Syndrome
3. Candida/Thrush
4. Cervical Pathologies (Cell Irregularities)
When do weekly non-stress testing screens begin in pregnancy?
Non-stress testing begins at 32 weeks of pregnancy
What is used to check for fetal growth issues?
Ultrasound
Which drug is used to prevent HIV transmission from mother to child during the period of pregnancy, labor (IV prior to birth), and delivery?
Azidothymidine (AZT)/Zidovudine
Trade name: Retrovir
Pharmacologic: Nucleoside/nucleoide reverse transcriptase inhibitor AZT (ZDV)
Dose: 200 mg TID or 300 mg BID
When is azidothymidine (AZT) started in the pregnancy of a women with HIV?
Azidothymidine (AZT) should be started within the 2nd trimester of pregnancy (12-28 wks)
HIV transmission from mother to fetus can occur due to...
1. Breastfeeding
2. Amniocentesis
3. Mixing blood in utero
How many hours should a woman wait after consuming alcohol to breastfeed her baby?
2 hours
Complications from illicit drug use while the fetus is in utero:
1. Intrauterine asphyxia (hypoxemia - low oxygen in blood, hypercapnia - excess carbon dioxide in blood, and respiratory/metabolic acidosis)
2. Intrauterine infection (STD, HIV, Hepatitis)
3. Lower APGAR scores
4. Alterations is birth weight (small gestational age)
What drug counteracts respiratory depression caused from opioids?
Naloxone/Narcan
Complications of illicit drug abuse during pregnancy:
1. Respiratory distress
2. Jaundice
3. Methamphetamine users increase occurance of cleft lip/palate, cardiac abnormalities, microcephaly, and low birth weight
4. Congenital anomalies and growth restriction
5. Behavior issues (disorganization, decreased interactive behavior and engagement in auditory/visual stimuli)
Cocaine use during pregnancy can cause what complications in the fetus?
1. Microcephaly
2. IUGR (intrauterine growth restriction - small baby)
3. Cardiac and genitourinary defects
4. High risk of SIDS (sudden unexpected infant death)
What does azidothymidine/zidovudine do?
1. Decreases viral load
2. Increases CD4 T-cell counts
3. Delays onset of disease symptoms
4. Reduction of symptom severity
Side affects of azidothymidine/zidovudine?
1. Anemia
2. Neutropenia (lack of white blood cells - neutorphils)
3. Lactic acidosis (low pH in body tissues/blood)
4. Hepatotoxicity (liver toxicity)
Gestational diabetes mellitus occurs in typically what trimester?
2nd trimester
Diabetes mellitus definition
Endocrine disorder of carbohydrate metabolism resulting from inadequate production or use or insulin.
Where is insulin produced?
Insulin is produced by beta-cells of the islets of Langerhans in the pancreas
Purpose of insulin
Lowers blood glucose to move from the blood into muscle and adipose tissue cells
What happens during the first trimester in a pregnant woman with diabetes?
The need for insulin frequently decreases
When does insulin requirements begin to rise during pregnancy?
2nd trimester
What may diabetes in pregnancy cause without careful monitoring?
1. high risk of birth defects
2. hypertension
3. eclampsia
4. oversized fetus
5. risk of ketoacidosis (fetal death may result)
6. nephropathy
7. retinopathy
When is diagnostic testing done for gestational diabetes?
24-28 weeks
What type of test is down for gestational diabetes at 24-28 weeks?
OGTT (oral glucose tolerance test)
What does the OGTT consist of?
75 g oral glucose solution taken after fasting. Plasma blood of these levels determine GDM (gestational diabetes):

Fasting: 95 mg/dL
1 hr: 180 mg/dL
2 hr: 155 mg/dL
3 hr: 140 mg/dL
What A1C level determines gestational diabetes?
6.5% or higher A1C
What are two analog insulin brands a pregnant woman with diabetes can take?
1. Aspart
2. Lispro
NOT PO!