Obgyn 51: Vulvar And Vaginal Neoplasia

Front 1

2 kinds of preinvasive vulvar neoplasia

Back 1

squamous
nonsquamous

Front 2

2 kinds of nonsquamous preinvasive vulvar neoplasia

Back 2

Paget's disease
melanoma in situ

Front 3

the 3 preinvasive vulvar neoplasia are distinguished using

Back 3

immunohistochemical stains

Front 4

squamous preinvasive vulvar neoplasia is called ___

Back 4

vulvar intraepithelial neoplasia (VIN)

Front 5

VIN III is aka ___

Back 5

vulvar carcinoma in situ

Front 6

3 RFs associated with ___ VIN

Back 6

HPV
smoking
immunodeficiency

Front 7

the 2 HPV serotypes associated with VIN

Back 7

16
18

Front 8

clinical presentatioin of VIN (3)

Back 8

vulvar pruritus/irritation
perineal burning
dysuria

Front 9

in contrast to CIN, VIN is often ___

Back 9

multifocal

Front 10

tx for unifocal VIN

Back 10

wide local excision

Front 11

desired margin for VIN local excision

Back 11

5-10 mm

Front 12

tx for multifocal VIN

Back 12

vulvectomy

Front 13

conservative tx for multifocal VIN is considered for ___
tx is ___

Back 13

young patients
5-FU

Front 14

after VIN tx, patients get followup ___ every ___ m for ___ years

Back 14

colposcopy
6
2

Front 15

Paget's disease is associated with ___ (malignancy)

Back 15

adenoca

Front 16

lesions of Paget's disease are initially ___ (4).
later they are ___ (2)

Back 16

velvety
red
thickened
hardened
white
scarred

Front 17

lesions of Paget's disease may be ___ or ___

Back 17

focal
diffuse

Front 18

tx for Paget's without adenoca

Back 18

wide local excision

Front 19

prognosis for metastatic Paget's disease is good/bad

Back 19

bad (fatal if spread to LNs)

Front 20

main site of vulvar cancer

Back 20

labia majora

Front 21

vulvar cancer mets to the ___ LNs

Back 21

superficial inguinal

Front 22

stage I vulvar cancer criterion

Back 22

tumor < 2cm

Front 23

stage II vulvar cancer:
tumor is ___ (2)
nodes are ___

Back 23

> 2 cm
confined to vulva + perineum
negative

Front 24

stage III vulvar cancer:
tumor is ___ (2)
nodes are ___

Back 24

any size
invading lower urethra/vagina/anus
positive on 1 side

Front 25

stage IV vulvar cancer (2)

Back 25

distant adjacent spread
distant mets

Front 26

staging of vulvar cancer is done ___ly

Back 26

surgically

Front 27

main surgery for vulvar ca staging:
___ with ___

Back 27

radical local excision
inguinofemoral LN dissection

Front 28

stage I tx (2)
other stages get some form of ___

Back 28

wide radical loacl excision
inguinal LN dissection
vulvectomy