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56 Cards in this Set

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  • Back

Post partum hemorrhage definitions?

Bleeding >500 cc in svd


Bleeding > 1000 cc in c-section

Ddx of post partum hemorrhage


Uterine atony


Retained POC's


Placenta accreta


Lacerations of vagina or cervix


Treatment process for uterine atony

1. Pitocin


2. Methergine


3. Prostin


4. D&C

Surgical management of postpartum hemorrhage?

D&c


Then laporotomy


Then artery ligation


Then hysterectomy


Possibly IR e!bolization

How to treat endometriosis?

Medical management can alleviate symptoms



Only surgical management can increase fertility

How do previous abortion, uncomplicated pregnancy termination, intrauterine adhesions, and insulin dependent diabetes effect risk of spontaneous abortion?

None effect except insulin dependent diabetes, which increases the risk

Treatment of cervical incompetence?

Cervical cerclage in the second trimester

Uterotonics used in postpartum hemorrhage?

Methergine



Prostaglandins



Oxytocin

Which medication is contraindicated in pre ecclampsia and hypertension? Typically used in post partum hemorrhage.

Methylergonovine

Which medication is should not be used in asthma patients? Typically used in post partum hemorrhage.

Hemabate ( prostaglandin F2-alpha)

What type of factors lead to uterine inversion?

Factors that lead to an over distended uterus

In relation to post partum hemorrhage, what does the increased number of c sections increase the risk of?

Placenta accreta

What increases risk of placental retainment?

Prior c section


Uterine leiomyoma


Prior uterine curettage


Succenturiate lobe of placenta

What type of procedure can be done in a uterine atony picture of conservative management had failed?

B Lynch suture

What are patients with abnormal uterine bleeding at risk for?

Endometrial cancer from unopposed estrogen

In abnormal uterine bleeding, what must be ruled out before endometrial ablation?

Endometrial carcinoma

Which type of disorder may present like menstrual symptoms in a YOUNG woman?

Clotting disorders

When are you allowed to observe an endometrial polyp?

If <1.5cm

Ob gyn side effect of imipramine?

Increased prolactin

Of you are hypothyroid, what level is your prolactin?

Elevated

Lab values in exercise induced hypothalamic amenorrhea?

Normal FSH



Low estrogen

Purpose of the clomiphene challenge test?

To determine ovarian reserve

Does rise in basal body temp occur before or after ovulation??

AFTER

Normal cycle length?

21-35 days

Acronym for abnormal uterine bleeding

PALM (polyp adenomyosis leiomyoma malignancy/hyperplasia)


COEIN (coag ovulatory dysfxn endometrial issues iatrogenic not otherwise specified)

Tell tale imaging sign of adenomyosis?

Differing diameter of uterine wall in AP view

DX of pcos, need 2 of 3 ransons criteria

An ovulation/menstrual irregularity


Hyper androgenism


Polycystic ovaries (string of pearls)

Moa and use of tranexamic acid?

Prevents breakdown of fibrin



Non hormonal



Only use 5 days per month

2 things to know about depoprovera

+weight gain (stimulates appetite)


+irregular bleeding


Depolupron side effects

(Decreases fibroid size)


Menopausal symptoms


Osteoporosis

Risk of placenta previa accreta if 3 prior c sections?

67%

Which is more common and has higher chance o malignancy?complete or partial molar pregnancy?

Complete

Pathognomonic feature of complete mole?

Snowstorm appearance

Most common presentation of a partial molar pregnancy?

Missed abortion

Symptomatology of molar pregnancy?

Similar to preeclampsia



Due to HCG

Preop eval of molar pregnancy?

1. Baseline HCG


2. Baseline CXR to check for metastatic disease


Risk of congenital anomalies or complications in future pregnancies after molar pregnancy?

No increase in anomalies

Does a persistent Gestational Trophoblastic Neoplasia follow a molar pregnancy or a normal pregnancy?

BOTH (see a lack of a fall in hCG)

Biopsy or don't biopsy a metastatic gtn?

Don't! It will bleed!

Cure for malignant forms of GTN?

Chemotherapy (methotrexate or actinomycin d)

Metastatic gestational trophoblastic disease, high risk

Not a molar pregnancy


>4 months since pregnancy


Titer >100,000


Failed chemo


Not in chest



NO CURE

Cell composition of placental site tumors?

Intermediate cytotrophoblastic cells

What marker do you follow for a placental site tumor?

Human placental lactogen

What is needed to make the diagnosis of endometriosis?

Tissue biopsy confirming endometrial tissue

First line treatment for endometriosis?

OCP'S and NSAIDS

Endometriosis option if still trying to get pregnant?

Daily oral medroxyprogesterone

Moa of danazol in endometriosis? Side effect profile?

Suppresses LH and FSH leading to hypoestrogenic state leading to endometrial atrophy



Lots of androgenic side effects

Benefit of GnRH agonists vs danazol?

Less androgenic side effects



But still hypoestrogenic so menopausal symptoms

How long does sperm production take?

70 days

Moa of the #1 medication for ovulation induction?

Clomiphene



SERM that inhibits estrogen mm binding in the pituitary leading to increased GnRH which simulator follicle development in the ovaries

Malignant uterine tumor in young individual, what marker don't you use and why?

CA-125


Because most likely it's a germ cell tumor (AFP and HCG)

Therapy for cervical cancer?

Radiation. Not surgery.

Molar pregnancy definition:

Abnormal proliferation of cytotrophoblast


Hydropic swollen villi


No fetal vessels -->no fetus

How to diagnose a molar pregnancy? Management?

US



Evacuation ( unless older, then hysterectomy)



Follow with HCG titers (0 by 12 weeks)

Persistent gestational trophoblastic disease labs?

Have HCG titers increase within a year

Treatment for PGTD

Chemotherapy


(Mac?)