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56 Cards in this Set
- Front
- Back
Post partum hemorrhage definitions? |
Bleeding >500 cc in svd Bleeding > 1000 cc in c-section |
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Ddx of post partum hemorrhage |
Uterine atony Retained POC's Placenta accreta Lacerations of vagina or cervix |
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Treatment process for uterine atony |
1. Pitocin 2. Methergine 3. Prostin 4. D&C |
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Surgical management of postpartum hemorrhage? |
D&c Then laporotomy Then artery ligation Then hysterectomy Possibly IR e!bolization |
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How to treat endometriosis? |
Medical management can alleviate symptoms Only surgical management can increase fertility |
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How do previous abortion, uncomplicated pregnancy termination, intrauterine adhesions, and insulin dependent diabetes effect risk of spontaneous abortion? |
None effect except insulin dependent diabetes, which increases the risk |
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Treatment of cervical incompetence? |
Cervical cerclage in the second trimester |
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Uterotonics used in postpartum hemorrhage? |
Methergine Prostaglandins Oxytocin |
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Which medication is contraindicated in pre ecclampsia and hypertension? Typically used in post partum hemorrhage. |
Methylergonovine |
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Which medication is should not be used in asthma patients? Typically used in post partum hemorrhage. |
Hemabate ( prostaglandin F2-alpha) |
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What type of factors lead to uterine inversion? |
Factors that lead to an over distended uterus |
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In relation to post partum hemorrhage, what does the increased number of c sections increase the risk of? |
Placenta accreta |
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What increases risk of placental retainment? |
Prior c section Uterine leiomyoma Prior uterine curettage Succenturiate lobe of placenta |
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What type of procedure can be done in a uterine atony picture of conservative management had failed? |
B Lynch suture |
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What are patients with abnormal uterine bleeding at risk for? |
Endometrial cancer from unopposed estrogen |
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In abnormal uterine bleeding, what must be ruled out before endometrial ablation? |
Endometrial carcinoma |
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Which type of disorder may present like menstrual symptoms in a YOUNG woman? |
Clotting disorders |
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When are you allowed to observe an endometrial polyp? |
If <1.5cm |
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Ob gyn side effect of imipramine? |
Increased prolactin |
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Of you are hypothyroid, what level is your prolactin? |
Elevated |
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Lab values in exercise induced hypothalamic amenorrhea? |
Normal FSH Low estrogen |
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Purpose of the clomiphene challenge test? |
To determine ovarian reserve |
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Does rise in basal body temp occur before or after ovulation?? |
AFTER |
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Normal cycle length? |
21-35 days |
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Acronym for abnormal uterine bleeding |
PALM (polyp adenomyosis leiomyoma malignancy/hyperplasia) COEIN (coag ovulatory dysfxn endometrial issues iatrogenic not otherwise specified) |
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Tell tale imaging sign of adenomyosis? |
Differing diameter of uterine wall in AP view |
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DX of pcos, need 2 of 3 ransons criteria |
An ovulation/menstrual irregularity Hyper androgenism Polycystic ovaries (string of pearls) |
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Moa and use of tranexamic acid? |
Prevents breakdown of fibrin Non hormonal Only use 5 days per month |
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2 things to know about depoprovera |
+weight gain (stimulates appetite) +irregular bleeding |
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Depolupron side effects |
(Decreases fibroid size) Menopausal symptoms Osteoporosis |
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Risk of placenta previa accreta if 3 prior c sections? |
67% |
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Which is more common and has higher chance o malignancy?complete or partial molar pregnancy? |
Complete |
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Pathognomonic feature of complete mole? |
Snowstorm appearance |
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Most common presentation of a partial molar pregnancy? |
Missed abortion |
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Symptomatology of molar pregnancy? |
Similar to preeclampsia Due to HCG |
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Preop eval of molar pregnancy? |
1. Baseline HCG 2. Baseline CXR to check for metastatic disease |
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Risk of congenital anomalies or complications in future pregnancies after molar pregnancy? |
No increase in anomalies |
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Does a persistent Gestational Trophoblastic Neoplasia follow a molar pregnancy or a normal pregnancy? |
BOTH (see a lack of a fall in hCG) |
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Biopsy or don't biopsy a metastatic gtn? |
Don't! It will bleed! |
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Cure for malignant forms of GTN? |
Chemotherapy (methotrexate or actinomycin d) |
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Metastatic gestational trophoblastic disease, high risk |
Not a molar pregnancy >4 months since pregnancy Titer >100,000 Failed chemo Not in chest
NO CURE |
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Cell composition of placental site tumors? |
Intermediate cytotrophoblastic cells |
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What marker do you follow for a placental site tumor? |
Human placental lactogen |
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What is needed to make the diagnosis of endometriosis? |
Tissue biopsy confirming endometrial tissue |
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First line treatment for endometriosis? |
OCP'S and NSAIDS |
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Endometriosis option if still trying to get pregnant? |
Daily oral medroxyprogesterone |
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Moa of danazol in endometriosis? Side effect profile? |
Suppresses LH and FSH leading to hypoestrogenic state leading to endometrial atrophy Lots of androgenic side effects |
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Benefit of GnRH agonists vs danazol? |
Less androgenic side effects But still hypoestrogenic so menopausal symptoms |
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How long does sperm production take? |
70 days |
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Moa of the #1 medication for ovulation induction? |
Clomiphene SERM that inhibits estrogen mm binding in the pituitary leading to increased GnRH which simulator follicle development in the ovaries |
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Malignant uterine tumor in young individual, what marker don't you use and why? |
CA-125 Because most likely it's a germ cell tumor (AFP and HCG) |
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Therapy for cervical cancer? |
Radiation. Not surgery. |
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Molar pregnancy definition: |
Abnormal proliferation of cytotrophoblast Hydropic swollen villi No fetal vessels -->no fetus |
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How to diagnose a molar pregnancy? Management? |
US
Evacuation ( unless older, then hysterectomy)
Follow with HCG titers (0 by 12 weeks) |
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Persistent gestational trophoblastic disease labs? |
Have HCG titers increase within a year |
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Treatment for PGTD |
Chemotherapy (Mac?) |