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62 Cards in this Set
- Front
- Back
O2 is tranferred from uterine circulation to umbilical circulation by?
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Passive Diffusion
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Indicators of Normoxemic state include:
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"Net lactate uptake by the fetus,Small amounts of hydrogen ion are transferred from fetus to mother, No increase in oxygen consumption occurs when maternal oxygen levels increase,Healthy fetus has a normal basal pH
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Fetal Oxidative Metabolism: Uterine Uptake is what 2 components
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1)Placental Comsumption (40% of utake at term, higher mid-term due to high carb and A.Acid metabolism 2) Umbilical O2 consumption is uptake by fetus
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Five factors Fetal O2 consumption
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Substrate Availability. Fetal: Growth, Activity, Hormone Status, Organ Metabolism.
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Is O2 fetal O2 consumption for growth necessary?
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No…not required to survive. Can be eliminated during high stress times. May lead to IUGR if prolonged
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Factors increasing Fetal Demand for O2
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Increased: Fetal Activity, Glucose Uptake (mom's high BG) and increase Hormone secretion
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Factors decreasing Fetal Demand for O2
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Mom's Hypoxemia, Low uterine or placental blood flow, placenta abnormal, fetal disorder
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Normal fetal growth is from
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Adequate metabolic substrates and fetus able to use it
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AGA
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Appropriate for Gestational Age. Wt b/w (10-90%) "for age"
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LGA
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Large for Gestational Age. Wt. >90% for age.
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SGA
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Small for Gestational Age. Wt. <10% for age
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What terms descibe birth wt. "Independent of Gest-Age
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LBW,VLBW,ELBW (low, verylow, Extrm low…birth wt.) 2500, 1500,1000 gms
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LBW
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<2500 gm
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VLBW
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<1500 gm
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ELBW
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<1000 gm
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Factors of Fetal Circulation
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"Fetal Oxygen Transport,Regulation of Fetal Blood Volume,Unique Fetal Circulatory Pattern, Various Factors that Control the Distribution of Blood Flow
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Oxygen content of fetal blood is determined by what formula?
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[Hgb] * HGB02 (bound) + constant 1.39 ml O₂/g Hgb Hgb (oxygen-carrying capacity of hemoglobin)
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Amount of oxygen dissolved in fetal plasma is?
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insignificant
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Normal fetal Hgb is __g/dl?
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18 g/dl
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Oxygen-carrying capacity of fetal blood should be
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25 ml O₂/dL – this is theoretical as fetal Hgb never approaches complete saturation @ low PO2
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P:50 for Fetus v. Mom ___mm Hg v. ___ mm HP
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Fetal Po2 is 19-21mm and mom's 27 mm Hg
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Per Rich. How does ocyhemoglob curve differ b/w mom and fetus?
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Fetus stays "locked and loaded" can drop to po2"19-21) and stays 50% saturated (@P:50)
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Fetal Hemoglobin does not interact as well with
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with DPG to stabilize the deoxygenated hemoglobin as maternal Hemoglobin does
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fetal hemoglobin has less DPG, less deoxy:hgb affinity and more…
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affinity for O2, so it takes it from mom *With emphasis*
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Fetal cardiac output is
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biventricular (also called combined ventricular output) "BV-CVO" due to ductus arteriosus
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Fetal Systemic and Pulmonary Circulations are
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PARALLEL, whereas postnatal circulations are in series
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The reason for parallel circulation is obvious
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fetal lungs do not participate in blood oxygenation
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almost complete right-to-left shunt is due to
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ductus arteriosus
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Can fetus increase their CVO in utero
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They cannot! …even during periods of stress (damn patent ductus arteriosus)
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Does fetal PNS or SNS develop first and which is more developed
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The PNS is developed first, thus the baseline FHR at 40 weeks gestation is < the baseline at 26 weeks gestation
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As the head decends into the pelvis, the ICP___?
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Increases…Ouch! "Hello there mom...stress me out with a head squish"
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Redistribution of circulation includes?
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"Decreases perfusion of the splanchnic organs, kidneys, and skin-Preservation of blood flow to skeletal muscle & bone-Augmented blood flow to the heart, brain, placenta, & adrenal glands-Cardiac output does not change-Fetal pH decreases as a result of these compensatory mechanisms
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FHRM: External (Indirect)
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Detected through maternal abdominal wall, no membrane rupture, doesn't quantify uterine pressure
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FHRM: Internal (Direct)
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"Wire electrode to the scalp of the fetus, requires rupture of membrane & partially dilated cervix
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Average FHR __bpm
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110-160
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"Tachy" FHR ___bpm
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>160
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"Tachy" FHR problems
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Prolonged hypoxemia (result of catecholamine secretion and SNS activity),Maternal Fever,Intrauterine infection,Medications (Terbutaline (β-adrenergic agonist), Atropine)
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"Brady" FHR ___ bpm
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<110 for 2 min.
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Why "Brady" FHR?
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Fetal initial response to acute hypoxemia, or maternal HoTN
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What is Variability?
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The irregularity of the FHR baseline from the competing effects of the PSNS and SNS
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Variability Describes?
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small HR changes in the FHR
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"What is the single, best non-invasive clinical indicator of fetal well-being?"
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Variability
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Short-term variability (beat-to-beat variability) results from the influence of ?
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the PSNS
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Long-term variability is?
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Rhythmic fluctuations in the FHR basline that are seen over a 5-10” tracing
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Normal (LT variability) frequency of such waves is
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3-5 cycles/min
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Lack of variability results from
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hypoxemia and the decompensation of cerebral blood flow & O₂ delivery
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How should you manage mom's BP?
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Keep it up…SBP >95
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A Periodic Changes in FHR called an acceleration is
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An abrupt increase in FHR (<30 Seconds)
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What is the mechanism for an accelaration?
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"Fetal Movement,Uterine Contractions,Umbilical Cord Occlusion,
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Periodic Changes in FHR precludes the presence of significant
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fetal metabolic acidosis (reassuring)
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"Early Decelerations are from what three factors?"
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"1) Occur simultaneously with uterine contractions and usually are <20 bpm below baseline-2) Onset and offset of each -decel coincides with the onset and offset of the uterine contraction-3) Occurs as a result of vagal response to head compression during labor
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"Late Decelerations are not good…why?"
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"1) Begin 10-30 seconds after the beginning of a uterine contraction and end 10-30 seconds after the end of the uterinecontraction::2) Smooth and Repetitive::3) Classic sign of uteroplacental insufficiency and hypoxia
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What is the "OMINOUS SIGNAL OF FETAL DISTRESS!"
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COMBINATION OF LATE DECELS AND DECREASED/ABSENT FHR VARIABILITY
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Describe Variable Decelerations
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"Vary in depth, shape, and/or duration:Abrupt in onset and offset
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What is the likely cause of variable decels
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"Believed to be a result of vagal response to either umbilical cord compression or to substantial head compression during pushing
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Healthy fetus typically can tolerate mild-to-moderate variable decels not below ___BPM
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<80 BPM is bad
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Fetal Distress is reassuring” vs. “non-reassuring”, what is this?
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"Reassuring – suggest a restoration of confidence by a particular pattern:Non-reassuring – “inability to remove doubt”
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"What's the classic sign of utero-placental insufficiency and hypoxia?"
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Late Decels
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What did saf says "mirrors the contractions"
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early decels
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What's a contraction that just won't let up?
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Titanic
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What is the main thing anes can do to treat fetal brady and late decels
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Fix the HoTN!
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Per Rich. Periodic changes are actually…
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Periodic changes are FHR accelerations or decelerations that occur with contractions. Decelerations are routinely described as early, late, or variable.
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