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16 Cards in this Set
- Front
- Back
COCP
Hormones + amounts Action, SFX |
Ethynylestradiol (oest) + desogestrel (prog)
20-30 μg Much higher than physiological Suppression of LH, FSH, ovulation Atrophic endometrium Altered cervical mucous SFX: ↑triglycerides |
|
POP
Actions , actions of ↑dose Time limit for taking daily medication Use post delivery, breast feeding, breast cancer |
Atrophic endometrium
Cervical mucous hostile to sperm ↑dose: central inhibition of ovulation 2nd gen: levonorgestrel, norethisterone Must be taken <3 hrs late 3rd gen: desogestrel Can be taken <12 hrs late YES – post delivery, breast feeding NO – breast cancer |
|
Progesterone injection
How often SFX |
Every 12 wks
Delay in return of fertility |
|
Progesterone implant
Example, SFX |
Nexplanon
Lasts 3 yrs SFX: heavy bleeds |
|
IUD
SFX |
Heavy bleeds
|
|
IUS
Actions, SFX Lasts how long |
↑cervical mucous
↓endometrial proliferation 3-5 yrs Initial ↑PID ↑proportion ectopic |
|
Emergency contraception
Types, usage, effectiveness |
Copper IUD
W/in 5 days ~100% effective Levonorgestrel 1.5mg PO <72 hrs ↓ovulation ~75% effective EllaOne ↓ovulation Taken <120hrs |
|
PP breast feeding
Effects on fertility |
BF→↓GnRH →↓ovulation
BF 10/day >98% effective |
|
GnRH agonists
Used to treat what Can cause what |
Tx for fibroids + endometriosis
Can cause menopause |
|
Premature ovarian failure
Before what age Appearance of ovary Cause |
<45
Ovary appears menopausal ?AID – 50% have autoAb |
|
Resistant ovary syndrome
PC Appearance of ovary |
Premature menopause
Ovary looks normal |
|
Menopause Rx
|
Oestrogen: ↓ bone loss
Progesterone: endometrial protection HRT Local oestrogen for lower genital tract symptoms |
|
HRT – oestrogen
Oestrogen:oestrone SFX |
Oestrone/oestradiol/equine oestrogen
Oestradiol –Liver→Oestreone Oestrogen:oestrone = 1:2 Reverse of premenopausal SFX: ↑VTE, ↑thyroid binding globulin |
|
HRT – progesterone
SFX, ways to avoid SFX |
++PMS like SFX
Boating, mastalgia, mood swings Combine w/ oestrogen→↓SFX, Ø bleed |
|
Tibolone
What is it Actions SFX |
HRT – synth steroid
Androgenic, oestrogenic, progesteronic activity SFX: ↓libido |
|
Platelets
When is it considered gestational thrombocytopenia What are the cut offs for: Epidural Sx Commence Rx |
>28/40: Gestational thrombocytopenia
<28/40: Not preg related, probably ITP Ø epidural <80 Ø Sx <100 Start Rx if <50 |