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16 Cards in this Set

  • Front
  • Back
COCP
Hormones + amounts
Action, SFX
Ethynylestradiol (oest) + desogestrel (prog)
20-30 μg
Much higher than physiological

Suppression of LH, FSH, ovulation
Atrophic endometrium
Altered cervical mucous

SFX: ↑triglycerides
POP
Actions , actions of ↑dose
Time limit for taking daily medication
Use post delivery, breast feeding, breast cancer
Atrophic endometrium
Cervical mucous hostile to sperm

↑dose: central inhibition of ovulation

2nd gen: levonorgestrel, norethisterone
Must be taken <3 hrs late

3rd gen: desogestrel
Can be taken <12 hrs late

YES – post delivery, breast feeding
NO – breast cancer
Progesterone injection
How often
SFX
Every 12 wks

Delay in return of fertility
Progesterone implant
Example, SFX
Nexplanon

Lasts 3 yrs

SFX: heavy bleeds
IUD
SFX
Heavy bleeds
IUS
Actions, SFX
Lasts how long
↑cervical mucous
↓endometrial proliferation

3-5 yrs

Initial ↑PID
↑proportion ectopic
Emergency contraception
Types, usage, effectiveness
Copper IUD
W/in 5 days ~100% effective

Levonorgestrel
1.5mg PO <72 hrs
↓ovulation
~75% effective

EllaOne
↓ovulation
Taken <120hrs
PP breast feeding
Effects on fertility
BF→↓GnRH →↓ovulation
BF 10/day >98% effective
GnRH agonists
Used to treat what
Can cause what
Tx for fibroids + endometriosis

Can cause menopause
Premature ovarian failure
Before what age
Appearance of ovary
Cause
<45

Ovary appears menopausal

?AID – 50% have autoAb
Resistant ovary syndrome
PC
Appearance of ovary
Premature menopause

Ovary looks normal
Menopause Rx
Oestrogen: ↓ bone loss

Progesterone: endometrial protection

HRT

Local oestrogen for lower genital tract symptoms
HRT – oestrogen
Oestrogen:oestrone
SFX
Oestrone/oestradiol/equine oestrogen


Oestradiol –Liver→Oestreone
Oestrogen:oestrone = 1:2
Reverse of premenopausal

SFX: ↑VTE, ↑thyroid binding globulin
HRT – progesterone
SFX, ways to avoid SFX
++PMS like SFX
Boating, mastalgia, mood swings

Combine w/ oestrogen→↓SFX, Ø bleed
Tibolone
What is it
Actions
SFX
HRT – synth steroid
Androgenic, oestrogenic, progesteronic activity

SFX: ↓libido
Platelets
When is it considered gestational thrombocytopenia

What are the cut offs for:
Epidural
Sx
Commence Rx
>28/40: Gestational thrombocytopenia
<28/40: Not preg related, probably ITP

Ø epidural <80
Ø Sx <100
Start Rx if <50