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52 Cards in this Set
- Front
- Back
normal BP
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< 120/80
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BP stabilizing mechanisms
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1) arterial baroreceptors
2) regulation of fluid volume 3) renin-angiotensin 4) vacular autoregulation |
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meds causing hypertension
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estrogen (birth control)
steroids cyclosporins erythropoeitin (Procrit, Epogen) |
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Angiotensin is a powerful ...
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vasoCONSTRICTOR
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Classes of drugs for hypertension drug therapy
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diuretics
calcium channel blockers ACE (Angiotensin Converting Enzyme) inhibitors ARBs (Angiotensin II Receptor Blockers) Aldosterone receptor antagonists Beta-adrenergic blockers Central alpha antagonists Alpha-adrenergic antagonists |
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Alpha-adrenergic receptors work to ...
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cause vasoCONSTRICTION in peripheral vasculature when stimulated by norepinephrine
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Beta-adrenergic receptors work to ...
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cause vasoDILATION in blood vessels when activated by epinephrine
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Types of diuretics
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1) Thiazide (hydrochlorothiazide)
2) Loop (Lasix, Bumex) 3) Potassium-sparing (Aldactone) |
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Thiazide
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diuretic
prevents Na reabsorption in DCT eat foods high in K can cause hyperuricemia (gout) monitor K level periodically |
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Loop diuretics
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Lasix
Bumex |
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Central alpha antagonists
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Decrease sympathetic tone - produces vasoDILATION
Aldomet (methyldopa) Catapres (Clonidine) most common both cause sedation |
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Aldomet
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methyldopa
Central alpha antagonist SE: ortho hypo, fatigue, ED, Na & H2O retention, sedation |
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Catapres
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clonidine
Central alpha antagonist most common SE: ED, sedation, dry mouth, sleep disturbances May be given in patch (fewer SEs) |
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Alpha-adrenergic blockers
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block alpha-adreneric effects and so cause vasoDILATION
end in "zosin" (remember alpha/A to Z/zosin) Cardura (doxazosin) Minipres (Prazosin) Hytrin (terazosin) SE: ortho hypo, syncope w/1st dose, Na & H2O retention |
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Cardura
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dozazosin
Alpha-adrenergic blocker |
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Minipres
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Prazosin
Alpha-adrenergic blocker |
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Hytrin
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terazosin
Alpha-adrenergic blocker |
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Watch out for this with alpha-adrenergic blockers
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syncope with 1st dose
ortho hypo |
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Beta-adrenergic blockers
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decrease CO and reduce sympathetic tone
DOC for pts. w/ischemic heart disease, unstable angina, MI two types: cardio-selective and non-cardio-selective end in "lol" (remember: BETTY with sunBLOCK LOLling on the beach) atenolol, metoprolol, nadolol SE: bronchospasm, nightmares, depression, ED, may exacerbate HF |
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Atenolol
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Beta-blocker
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Metoprolol
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Beta-blocker
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Nadolol
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Beta-blocker
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Calcium channel blockers
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block movement of extracellular Ca into cells, causing vasoDILATION
Norvasc (amlodipine), Isoptin (verapamil), Caridizem (diltiazem) SE: bradycardia, dizziness, peripheral edema, gingival hyperplasia, constipation, headache, dry cough avoid grapefruit juice, high-fat meals, limit caffeine |
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Norvasc
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amlodipine
Calcium channel blocker |
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amlodipine
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Norvasc
Calcium channel blocker |
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Isoptin
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verapamil
Calcium channel blocker |
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verapamil
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Isoptin
Calcium channel blocker |
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Cardizem
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diltiazem
Calcium channel blocker |
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diltiazem
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Cardizem
Calcium channel blocker |
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ACE Inhibitors
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inhibit angiotensin converting enzyme
end in "pril" (remember the month APRIL --> ACEPRIL) enalapril, captopril, lisinopril, ramipril SE: hyperkalemia, ortho hypo, angioedema, cough, acute renal failure avoid: oranges, bananas, salt substitutes |
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enalapril
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ACE inhibitor
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captopril
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ACE inihbitor
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lisinopril
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ACE inhibitor
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ramipril
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ACE inhibitor
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Angiotensin II Receptor Antagonists (ARBs)
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prevent action of angio II
end in "sartan" (remember: pirate captain Sartan says "ARrrrrB") losartan (Cozaar), irbesartan (Avapro), valsartan (Diovan) SE: hyperkalemia, can cause hepatitis - monitor liver enzymes |
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losartan
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Cozaar
ARB |
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Cozaar
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losartan
ARB |
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irbesartan
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Avapro
ARB |
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Avapro
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irbesartan
ARB |
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valsartan
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Diovan
ARB |
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loop diuretics
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Lasix (furosemide)
Bumex (bumetanide) |
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central alpha antagonists
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Aldomet (methydopa)
Catapres (clonidine) |
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alpha-adrenergic blockers
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Cardura (doxazosin)
Minipres (Prazosin) Hytrin (terazosin) |
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beta blockers
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atenolol
metoprolol nadolol |
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Calcium channel blockers
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Norvasc (amlodipine)
Isoptin (verapamil) Cardizem (diltiazem) |
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ACE Inhibitors
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enalapril
captopril lisinopril ramipril |
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ARBs
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losartan (Cozaar)
irbesartan (Avapro) valsartan (Diovan) |
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MAWDS
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for CHF Management
Medications - take as prescribed Activity - stay as active as possible while limiting symptoms Weight - daily; call MD if 2lb weight gain overnight Diet - fluid restrictions, low sodium Symptoms - report: dyspnea at rest, wheezes, weight gain, periph. edema |
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CMS Assessment
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Circulation
Movement Sensation - use 6 P's |
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6 P's
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pain
pallor pulselessness paresthesia paralysis poikilothermia |
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Virchow's triad
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1) venous stasis
2) endothelial damage 3) hypercoagulability (assessing for venous thrombosis) |
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Potassium-sparing diuretic
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spironolactone (Aldactone)
do not give w/ ACEIs or K suppls |