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43 Cards in this Set

  • Front
  • Back
1.Osteoporosis is .....
2. characterized by ______ and _______
3. Results in ________
1. Metabolic bone disease
2. Low bone mass + deterioration of bone tissue
3. increase in fragility fractures
1. What is a fragility fracture?
2. Body parts most susceptible (3)
1. results from minimal trauma (fall from standing) or no identifiable trauma

2. Hip + Spine + Wrist
Why is Osteoporosis considered a Paediatric Disease with Geriatric Consequences?

Can disease strike at any age? + Especially common for _________
- peak one mass reached in adolescence and if not built then, chances of osteo increase in older age
- early prevention necessary

Yes + White/Asian women over 50
Reduced quality of life for people with osteo why?
- disfigurement
- low self esteem
- reduced/loss of mobility
- decreased independence
Osteoporosis Symptoms
- pain
- reduced height
- curvature of the spine (KYPHOSIS)
Major Risk Factors
1. Greatest Predictor
2. others
1. Family History of osteoporotic fracture
2. 65 or older, other fractures, Celiac's, EARLY MENOPAUSE, Glucocorticoid therapy
Systemic Glucocorticoid Use
1. includes use of what meds ____ + ____
2. Diseases that use this treatment
1. Prednisone + cortisone
2. ASTHMA, Rheumatoid arthritis, Crohn's, Colitis, COPD
Minor Risk Factors
- rhematoid arthritis
- past history of hyperthyroidism
- low dietary Ca intake
- smoker
- excessive alcohol/caffeine
- low weight
Non modifiable risk factors
- previous fracture
- poor health/frailty
- advanced age
- female sex
- white/asian
How is Osteoporosis Measured?
1. Old method
2. New method
3. can better differentiate b/w ____ and _____
1. Radiographs
2. DEXA
3. Osteopenia vs Osteoporosis
How do you measure Bone Mineral Density?

BMD =
take sample of bone
wash out liquid bone marrow
remaining bone is half mineral and half protein

BMD = weight of mineral/volume bone
1. DEXA stands for______
2. great for predicting
3. Bone is compared to standard of _____
4. By looking at image how do we know state of bone?
1. Dual Energy Xray Absorption
2. whether a person will have a hip fracture
3. 25 year old bone (not age-comparable)
4. The more white = more bone density since rays are stopped by bone mineral/fat/water/protein
1. T score = ______
2. Normal Score
3. Osteopenia Score
4. Osteoporosis Score
5. Z score = _______
1. # of SDs from average 25 year old woman
2. > -1
3. -1 --> -2.5
4. < -2.5
5. # of SDs below age matched average
1. Age risk for men vs women
2. why?
1. 65 for men, much higher than women
2. Menopause is reason for earlier age, testosterone doesn't start changing until around 65
Bone Remodelling
1. completed every ___ to _____
2. Osteoclasts are
3. Osteoblasts are
1. every 3 to 4 months
2. clasts = excavate areas of crumbling/weakened bone
3. blasts = fill crevices w/ material that calcifies to form new bone
1. Age that bone stops growing and peak bone mass almost reached in men and women
2. exercise in children does what?
3. Absolute peak at age ____
1. Men = 20, women = 16
2. increases one growth by 5-15%
3. 30
Bone Mass Loss
1. What age do you begin losing bone mass + how much loss?
2. Women - how much loss after onset of menopause?
3. Men have accelerated bone loss after age ____ + how much loss compared to women?
1. 35 + 1%/year
2. 2-5% in first 5-10 years. 45% loss overall
3. age 65, 2/3 the loss of women
1. 2 Things to help maintain Bone Mass?
2. Age related factors that cause Osteoporosis
1. Physical activity + adequate Ca/Vit D
2. Inefficient bone remodelling + reduced Ca intake/absorption, poor Vit D status, hormonal changes
Some factors affecting bone mass Structure
Nutrition + Hormones + Exercise/Lifestyle
Falls +
Vitamin D and Age
1. After age ___ what happens?
2. found where? (3)
3. decline in what particular synthesis?
4. stored where? + northern phenomenon
1. skin doesn't convert vit D as well
2. Natural sunlight + fortified dairy products + meds
3. D3
4. Liver/fat + higher fat storage in north makes up for reduced sun exposure
1. Sunscreen with SPF ____ or more block vit D producing UV rays
2. Sun exposure - ______mins of exposure b/w what times is sufficient for VitD synth
3. Optimal Vit D Serum levels
1. 8
2. 5-30 mins b/w 10 am - 3pm
3. 75 nmol/L
Foods with Vit D
hard to reach daily recommendation through food alone
Salmon + Sardines + meat + eggs + liver + milk/margarine/butter
STUDY --> Ca attenuates bone loss in women
1. Recommended intake for young adults
2. for older adults
3. excess may lead to ______
4. Calcium sources
5. Keep intake below ______
1. 1000mg
2. 1200mg
3. kidney stones
4. cabbage + orange + cheese + milk
5. 2000mg (more than adequate if not better, effective up to an intake threshold)
Ca Supplements
1. recommended for who?
2. look for amount of _______Ca because the main ingredient is a compound called ________ so the pure amount of Ca is actually this
1. people not getting enough from food + unable to make diet change
2. elemental Ca, Calcium carbonate
2 types of Supplements + differences
1. Calcium Carbonate - inexpensive, best with food (tums)
2. Calcium Citrate - more expensive, okay on empty stomach
Body will do anything to maintain Ca levels because of it importance in ________________ so it may result to taking it from __________ despite the consequences of ________________
important to nerve conduction, contractions, heart function
may take from bones
doesn't care if osteo or kidney stones may develop later
1. Why are Ca dietary sources best?
Calcium guidelines by age:
2. 4-8
3. 6-18
4. 19-50
5. 50+
6. Preganant
1. elemental content is highest, higher absorption rate, lower cost
2. 1000
3. 1300
4. 1000
5. 1200
6. 1000
1. Influence of sufficient protein on fracture risk
2. effect of insufficient protein
3. Protein recommendations in g/kg vs RDA
4. when can protein promote bone loss?
1. reduces fracture risk
2. Catabolism --> decreased mobility --> increased risk of falling/fracture
3. 1g/kg --- RDA = 0.8g/kg
4. when Ca is inadequate
1. Vegetarian diets are insufficient in _____ and ____
2. Vegan diets don't get enough ____ and ___ and ____
3. 5 positive effect nutrients for bone health (MMPZK)
4. 4 things that are bad in excess
1. Ca and protein
2. Ca, protein and Vit D
3. Magnesium, Managanese, Phosphorus, Zinc, Vitamin K
4. Vit A, Na, Alcohol, Caffeine
1. Vit C key role = + Source
2. Phosphorus __% bone mass + Source
3. Magnesium increases ___
4. Lycopenes, contain ____, found in _____
1. Form bone matrix + citrus, tomatoes, cabbage, brocc
2. 50%, dairy, baked goods, legumes
3. bone quality
4. Antioxidants, found in tomatoes, grapefruit, watermelon
Nutrient deficiency risk populations (4)
1. Strict vegans
2. Restrictive Dieters
3. Frail/Elderly
4. Alcohol problem
Caffeine
1. contribute to ____ loss through the _______
2. detrimental amount = ____ per day
1. Calcium loss through Kidneys
2. FOUR per day
Smoking
Decreases _____ levels and lead to early _______
Decreases Estrogen levels
Leads to early Menopause
1. Hip protectors in LTC? pros/cons
2. Interventions for fall reduction
1. Pros - cost effective, reduction in fractures
Cons - Compliance, not effective in community
2. PA, balance training, home safety assessment, cataract removal
Physical Activyt
1. process explaining why its beneficial
2. improves..... but doesn't improve
1. PA places increased load on our body and it responds by increasing amount of bone
2. improves balance/coordination, flexibility/posture doesn't improve BONE DENSITY
PA
1. early prevention
2. Reversibility
3. Decreasing return
1. starting early is best way to prevent later trouble
2. Any gains lost quickly - maintenance is key
3. see changes initially then plateau
1. how many men over 50 have osteoporosis? __/__
2. what is main cause of osteo in men
3. diff b/w women and men, men more likely to ______
1. 1/8
2. less testosterone
3. later onset and more gradual decrease
4. men more likely to die/ be disabled by hip fracture
Reasons for less Osteo in men
1. greater peak bone mass
2. no menopause accerlating bone loss
3. don't live as long
4. less likely to fall
Fitness benefits
- Restful sleep
- health
- improved body comp
- improved bone density
- resistance to disease
- lower cancer risk
- lower CVD/ Type 2, anxiety/depression
- long life + better quality of life
1. Anaerobic activity characteristics
2. fuel source =

3. Endurance activities
4. Fuel Source
1.high intensity, short duration
2. fuel source = Glucose

3. Low to moderate intensity + long duration (aerobic)
4. Fuel source = FAT
% of total kcal
1. Carbs
2. Fat
3. Protein
1. 60-70%
2. 20-30%
3. 10-20%
Pre game diet features
1. what kind of food
2. how long before
3. avoid ____ and _____
1. easy to digest, carb rich
2. 3-4 hours before to allow stomach to empty
3. avoid fibre and fat
Post game diet features
1. why is it important
2. what kind of meal
3. how long after
1. enhances glycogen storage
2. high carb
3. within 2 hours