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30 Cards in this Set

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What are minerals?
minerals are inorganic elements (do not contain carbon)

They differ from all other nutrients in that they cannot be synthesized or broken down by any known form of life
Functions of minerals:
1. provide rigidity and strength to the structural components of body (bones, muscle, teeth).
2. activators of enzymes and hormones
3. maintenance of water and acid/base balance
4. muscle functioning
5. nerve functioning
6. blood clotting
Bioavailability of minerals:
bioavailability = how much of the nutrient is present in the food is how much will be available to the body
-influenced by the form in which minerals are consumed
-absorption can be inhibited by certain components in food
-minerals compete for absorption in the body (the level of one mineral in the body may affect the required level of another)
what defines a "major mineral"
it is found in the body in quantities above 5g.
what are the 7 major minerals?
1. calcium
2. phosphorus
3. potassium
4. sulfate
5. sodium
6. chloride
7. magnesium
Calcium and phosphorus' association:
calcium and phosphorus are often associated with one another because they tend to be present together in food and in the body.
-99% of calcium in the body is found in bone
-80% of phosphorus in the body is found in bone

*thus bone provides a ready supply (Reservoir) of Ca and P if the blood levels are low.
Role of Calcium
*calcium and phosphorus are essential to bone formation

-salts formed from calcium and phosphorus crystalize on collagen to form hydroxyapatite which adds the rigidity to bone.
-adding fluoride will create fluorapatite further hardens the teeth.

other functions:
-muscle contraction (including heartbeat)
-blood clotting
-nerve impulse transmission
-hormone secretion
-enzyme activity
Most abundant mineral in the body?
Calcium (phosphorus is the second most abundant)
Calcium's role in disease prevention (3 benefits of calcium)
1. low intakes of calcium are associated with colon and rectal cancer

2. calcium from milk products may play a role in maintaining a healthy body weight

3. calcium helps control blood pressure
RDA for calcium
adolescents = 1,300 mg
adults = 1,000 mg
elderly (esp. women) = 1,200 mg
peak bone mass
the maximum amt of bone that one acquires in one’s lifetime.. directly proportional to how bone mass is supported during adolescence (need optimal amt of calcium)

greatest amt of bone you’ll have is in your early 30s.. although the fastest growth of bone is in adolescence.
Factors that aid calcium absorption and factors that inhibit calcium absorption:
factors that aid:
1. ingestion with a meal
2. vitamin D
3. lactose

Factors that inhibit:
1. vitamin D deficiency
2. high fiber diet
3. high protein intake
4. phytates and oxalates
How does calcium absorption fluctuate?
as the need for calcium increases, the absorption increases:

more calcium is needed for growth...
infants and children absorb ~60% of calcium
pregnant women absorb ~50% of calcium
(and the loss of calcium from the kidneys is reduced in these instances)

an average adult absorbs 25% of calcium

(Absorption adjustments to calcium intake take time; increased absorption cannot fully compensate for reduced calcium intake)
bone density and aging:
no matter what, by about age 30 you are no longer adding calcium to your bones (you have reached peak bone mass...

you can slow down the process of lost density by eating a calcium rich diet and participating in weight-bearing physical activity.
Role of Phosphorus
1. ≈85% is combined with calcium in the crystals of the bone and teeth

2. Phosphorous salts are buffers that help maintain the acid-base balance of cellular fluids

3. Part of DNA and RNA

4. Phosphorus compounds carry, store, and release energy in the metabolism of energy nutrients

5. Phosphorous compounds assist many enzymes and vitamins extracting the energy from nutrients

6. Forms part of phospholipids

7. Present in some proteins
symptoms of low phosphorus in the blood:
1. decreased appetite
2. anemia
3. muscle weakness
4. bone pain
5. increased susceptibility to infections

*deficiencies are not common (Phosphorus is wide-spread in food)

*animal protein is the best source of phosphorus
Calcium, Phosphorus, and vit. D deficiency:
deficiency of any 3 will cause abnormalities of the bones and teeth

osteoporosis:
-excessive mobilization of minerals from bones
-mineral content of bones is normal
-the mass of bones is reduced
Distribution of magnesium in the body:
55% in bones
27% in muscles
18% in all cells
Role of Magnesium
*Critical to many cell functions

1. Assists in the functioning of more than 300 enzymes

2. Release and use of energy from energy-yielding nutrients

3. Directly affects the metabolism of:
-Potassium
-Calcium
-Vitamin D

4. regulates heart rhythm and body temperature

5. part of the protein making machinery

6. necessary for the release of energy

7. promotes relaxation of muscles (calcium promotes the contraction)

8. promotes resistance to tooth decay by holding calcium in tooth enamel

9. essential for DNA and protein synthesis
RDA for magnesium:
males: 400 mg/d
females:310 mg/d
Where do we find magnesium
because magnesium is part of chlorophyll, it is abundant in vegetables.

it is also found in legumes, whole grains, and hard water

it is easily washed and peeled away during processing
Magnesium deficiency
it is quite rare (it is common in both animal and plant sources of food)
in addition, the kidneys can limit excretion when intake is low

deficiency develops in alcohol abuse and prolonged vomiting

symptoms:
-hallucinations that can be mistaken for mental illness or drunkenness
-Hyperirritability
-skin Lesions
-edema
-Ca deposition in Tissues
benefits of drinking water high in magnesium:
Those drinking water that provides adequate magnesium experience a lower incidence of sudden death from heart failure than other people

Magnesium deficiency may make the heart unable to stop spasms once they start
Role of Sulfate:
Required for the synthesis of many important sulfur-containing compounds:
-certain antioxidants
-thiamin
-sulfur-containing amino acids (methionine, cysteine and cystine)
^gives rigidity to skin, hair, and nails
Glutathione
Glutathione is the primary antioxidant in the body

It is synthesized via the sulfur containing amino acid, cysteine

Glutathione deficiency can be induced by protein-deficient diets that are also low in sulfur amino acids


Low glutathione levels in elderly subjects have been theorized to accelerate the aging process 


Low glutathione levels are seen in many chronic diseases, which could benefit from cysteine supplements or proteins rich in cysteine
how do you meet sulfate requirements?
there is no RDA set for sulfate... it is thoguht that if you meet your protein requirements, you will meet your sulfate requirements as well.
Deficiencies of sulfate?
there are no known deficiencies
Toxicity of sulfate?
From too much sulfate in water, either naturally occurring or from contamination

leads to:
-diarrhea
-colon damage
dietary intake of sulfur from:
corn, sunflower seeds, oats, chocolate, cashews, walnuts, almonds, and sesame seeds
S-Adenosylmethionine (SAMe)
Involved in numerous metabolic processes in the body that require sulfur 


Increasing levels of SAMe through supplementation may act as an effective antidepressant 


Used in treatment of osteoarthritis and alcoholic liver cirrhosis