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181 Cards in this Set

  • Front
  • Back
Respiratory quotient (RQ) is the ratio of CO2 produced to oxygen consumed. Excess CO2 production and increased RQ can lead to what adverse effect?
difficulty weaning from the ventilator
What would most likely contribute to weight loss in patients with COPD?
increased energy expenditure due to work of breathing
What potential side effect of medication used to treat COPD may limit dietary intake?
diarrhea, gastric irritation, dry mouth, and dysgeusia
MNT for patients with OSAS should focus on what?
weight reduction
What is a common complication of prednisone therapy that may require nutritional intervention?
hyperglycemia
GR is a 10y/o girl with cystic fibrosis complaining of weakness and lethargy and weight loss. In addition to adjusting oral enzyme supplements, what dietary recommendations would be appropriate?
extra salt, addition of vitamins and mineral supplements, high calorie intake
How much of an increase in energy expenditure has been reported in patients with COPD?
ten-fold increase
DR is hospitalized for pneumonia requiring ventilation >14days. What type of nutritional support should she receive given a normal GI function?
enteral nutrition via NG tube
What vitamin deficiency may occur in a patient taking long-term abx?
vit K
In addition to malabsorption, what factors contribute to osteopenia seen in pts with cystic fibrosis?
malabsorption, vit D deficiency, delayed puberty
What is considered first-line tx for pts with OSAS?
CPAP
a 9y/o girl with cystic fibrosis is brought to her PCP for foul-smelling stools and weight loss. What is the most likely cause of her weight loss?
malabsorption
What increases resting energy requirements and promotes los of weight and lean body mass in COPD pts?
increase in cytokines, decrease in levels of cell derived proteins, frequent and recurrent respiratory infections
What is the most likely etiology of elevated H&H in pt with COPD?
chronic hypoxia
What metabolic complications are patients with COPD and CHF on furosemide and prednisone at risk for?
hyperglycemia, hypokalemia
What calorie requirement should be used for individuals with acute renal failure?
20-35kcal/kg/day
MNT for patients prior to initiating dialysis restricts protein, why?
to slow progression of renal disease
What foods contain the highest amount of oxalate and should be limited in pts with calcium oxylate stones?
dark green, leafy vegetables
Side effects related to some immunosuppresive (post renal transplant) agents would require dietary recommendations including what?
hyperlipidemia
Restricting phosphate intake for those with chronic kidney disease may decrease severity of what?
vascular and soft-tissue calcificatons
Patients in chronic kidney disease taking what to control blood pressure may be at risk for developing hyperkalemia?
dietary salt substitutes, ACE inhibitors, Potassium sparing diuretics
A patient getting dialysis 3x/week with a BUN 65mg/dL, albumin 3.7g/dl, and creatnine 9.2mg/dl should consume how much protein daily?
60-65g/day
The kidney is essential in the metabolism of what metabolic conversion?
25(OH)D3 to 125(OH2)D3
What mechanism explains why moderate protein intake is advised for pts with nephrotic syndrome?
to reduce amino acid load in the glomerulus
What mechanism most likely explains anemia associated with chronic kidney disease?
decreased erythropoietin production
What is "dry weight" with regards to patients with chronic kidney disease?
weight of the pt minus the estimated amount of fluid retention
What are the daily protein requirements for the following pt?
46/m stage 4 CKD. Weighs 200lbs (90.7kg), an ideal BW and is not retaining fluid. Urine indicates protein loss of 2.1g/24h.
56.5g/day
What is likely to be tested with a 24h urine collection in a pt with Type 2 DM with elevated creatinine and BUN levels with suspicion of renal disease?
presence of RBCs, Protein excretion, Creatinine excretion
Who has the highest risk of developing breast cancer:
- pre-menopausal, BMI of 30
- pre-menopausal, BMI of 22
- post-menopausal, BMI of 30
- post menopausal, BMI of 40
post-menopausal, BMI of 40
What is the strongest and most consistent predictor of breast cancer risk?
weight gain during adulthood
Weight gain in what body area poses highest risk of colon cancer?
Abdomen
Dietary recommendations to reduce the risk of colorectal cancer include what about red meat intake?
maximum of 18oz cooked red meat per week with no processed meat consumption
Flavanoids are found in high concentrations in what foods?
- grapes and wine
- berries
- green tea
Consumption of foods made with soy may be protective against what type of cancer?
Breast
What is a good source of selenium to meet the 55mcg/day RDA?
Brazil nuts
An 84/m admitted to hospital with dehydration and pneumonia. At what point should cancer cachexia be suspected?
if he experienced unintentional weight loss greater than 5% over the previous month
What side effect of radiation treatment is most likely to affect a patient's nutritional status?
nausea and vomiting
What nutrition recommendation could help control nausea after treatment with chemotherapy?
consume clear or ice-cold drinks, eat small and more frequent meals
Alcohol users experience what types of cancers six times more often than non-drinkers?
oral cancer
RT is a 45/m with fam hx of cancer. He recently quit smoking and is eating healthier. What else can be recommended to reduce risk of developing cancer?
begin a regular physical activity program for 30 mins/day
In which of the following would tube feeding be useful?
- 2 days post coronary bypass in well-nourished pt
- folowing surgery for ischemic bowel with 50cm remaining
- seven days after a stroke in pt with aspiration when swallowing
- crohn's disease with small bowel obstruction
- Seven days post stroke in pt with aspiration
When is a surgically placed feeding tube, such as a jejunostomy indicated in a patient requiring long-term feeding?
When other abdominal surgery is scheduled.
When a pt is ambulatory and eating small amounts of food, what is the best method for administering supplemental tube feeding?
nocturnal cycle
What test is indicated when a pt receiving tube feeding and abx develops diarrhea?
stool for clostridia difficile
What is a proposed benefit of pre-biotics in enteral formulas?
normalizes intestinal flora
Which antioxidants are added to some enteral formulas?
Vitamins C and E
What is the preferred feeding tube placement in an ICU pt with a large hiatal hernia and documented GERD?
nasoenteric (nasojejunal or nasoduodenal)
Lack of enteral stimulation may contribute to what?
gut atrophy and higher infection risk
What formula density is appropriate for pt with normal fluid requirements?
1.0-1.2 kcal/mL
Formulas supplemented with glutamine are designed to accomplish what?
assist in controlling blood sugar
What is recommended for home infusion of an enteral formula via a jejunostomy?
cycled over 12 hours at night
Which of the following does NOT increase fluid requirements in pts receiving tube feeding?
- fiber-enriched formulas
- fistula poutput
- nausea
-diarrhea
Nausea
MNT for a pt with odynophasia (painful swallowing) includes which of the following?
- low-fat foods
- raw fruits and veggies
- spicy foods
- soft, blended foods
soft, blended foods
Parenteral nutrition is utilized in pts in what situations? (select 2)
- diminished motor capacity makes eating difficult
- GI tract is not funcitonal, accessible, or safe to use
- When pt has dementia
- enteral nutrition is not possible.
- GI tract is not functional, accessible, or safe to use
- Enteral nutrition is not possible
Central parenteral nutrition is indicated in which of the following?
- long-term parenteral nutrition support >7 days
- poor peripheral access
- moderate-to-severe elevated metabolic rate
- all of the above
All
When using peripheral parenteral nutrition solutions, what is the maxiumum allowable concentration to prevent vascular damage?
900 mOsm/Liter
According to ASPEN, what range is most commonly recommended when determining energy needs for parenteral nutrition?
20-35kcal/kg daily for adults
What range is recommended for protein needs for parenteral nutrition in severely stressed patients?
1.5-2.0 kcal/kg per day
In order to limit the potential side effects of linoleic acid on prostaglandin metabolism in pts receiving parenteral nutrition, soybean or sunflower lipid emulsions shoudl be limited to what?
<1g lipid/kg/24 hours
What is most likely the cause of complications in parenteral nutrition such as change in body temp, new onset shaking chills, leukocytosis, unexplained hyperglycemia?
catheter related blood stream infection
Potential complications of parenteral nutriition that must be monitored closely include what?
hyperlipidemia,
electrolyte imbalances
dehydration or fluid overload
What is the most common cause of large intestinal obstruction in an adult patient?
Hernia
What is the most common cause of large intestinal obstruction in an elderly patient?
colon cancer
What explains why low serum calcium levels must be adjusted in pts who also exhibit hypoalbuminemia?
calcium is bound to serum albumin
When a pt transitions from parenteral nutrition to oral feeding, when should parenteral nutrition be discontinued?
When the pt tolerates 75% of daily nutrition requirements through the oral diet.
What are the three major causes of malnutrition in COPD?
1. ppor nutritional intake
2. altered protein metabolism
3. hypermetabolism
Poor nutritional intake in COPD includes what?
- swallowing dysfunciton,
- decreased appetite,
- depression,
- med induced GI symptoms
- dyspnea
What causes altered protein metabolism in COPD?
increased inflammatory mediators,

altered leptin and anabolic hormone levels
___ in COPD is due to increased work of breathing, respiratory exacerbation, and medication
hypermetabolism
Factors causing poor nutritional intake in COPD are:
1. appetite reduced
2. frequent cough results in poor swallowing
3. severe dyspnea and fatigue = inability to prepare meals
4. depression from illness
5. hyperinflation of lungs - pressure on abdominal cavity and early satiety
6. oxyhemoglobin desat during eating.
7. medication side effects
8. medication causing inc. need for protein, calc. vit A, folic acid
9. medication alters levels of K+, Mg, cholesterol
What contributes to weight loss in COPD?
Multiple causes due to hypermetabolic state, altered protein metabolism, poor nutritional intake
What are ways of providing proper nutritional support to a ventilated patient?
1. enteral support
2. parenteral support
Why is it important that ventilated patients get nutritional support?
1. undernutrition leaves the susceptible to infections
2. undernutrition can make weaning from ventilator difficult due to decreased respiratory muscle strength for breathing.
Nutritional deficiencies in Cystic Fibrosis patietns include:
- kcals
- protein
- essential fatty acids
- fat-soluble vitamins
- beta-carotene
- zinc
- iron
- sodium
Patients with cystic fibrosis have ____ nutrient needs.
Increased - due to high protein catabolism, and energy exposure due to infections and malabsorption.
Nutritional deficiencies in cystic fibrosis are largely due to ___
malabsorption
What are salt and kcal needs for cystic fibrosis pts?
- added salt, high kcals, balanced meals, and nutrient-dense foods are important
- nutrition supplements between meals.
Pancreatic enzyme replacement in cystic fibrosis patients should include:
500-2500 units lipase per meal
What are the recommended needs of vitamins in cystic fibrosis?
- vit K, A, D, E
*often need 2x RDA to prevent deficiency due to malabsorption

- K: 2.5-5 mcg/week
- A: 10,000 IU/ day
- D: 800-1000 IU/day
- E: 200-400 /day
___ is usually caused by fat occlusion of upper airway.
Obstructive sleep apnea (OSA)
What are appropriate weight loss goals for pts with OSA?
- 5-10% loss can improve breathing and sleep patterns, also benefit from RD referral
- increase activity should start with low-intensity then build
What are common SxS of OSA?
-snoring
-excessive sleepiness
How does weight influence a woman's risk of breast CA?
- obesity linked to breast CA
- increased risk if weight gain post menopause. (none for pre-menopausal women)
- Women with BMI>40 had 60% inc. risk of dying formc cancers.
**Weight gain during adulthood is most consistent and strongest predictor of breast cancer**
What is the most consistent and strongest predictor of breast cancer?
Weight gain during adulthood
___ is strongly associated with inc. risk of colon, kidney, pancreatic, esophageal, endometrial, and post-menopausal breast CA
obesity
There is a 200-400% increase in occurance of endometrial cancer associated with BMI >than ??
25
Colon cancer occurs more frequently in ___
obese patients (abdominal fat seems to have signficant role)
Describe the impact of diet (meats and protein) vs cancer.
Red meat intake significantly increases risk of colorectal cancer.

Processed meats have been linked to increased risk stomach cancer
WHere are nitrates found?
cancer causing ntirosamines (nitrates and nitrites) are added to meats for preservation
Intake of red meat should be limited to how much to decrease risk of cancer?
18oz cooked red meat weekly
What meat sources should be excluded from a diet to aid in cancer prevention?
Avoid processed meats completely
___ are associated with inc. risk of colorectal, panreatic, and breast ca
HCAs (those who have high intake of well-done, fried, or bbq foods)
Total fat intake (does/ does not) alter cancer risk?
Does not
Diets high in animal fat are ____ associated with colorectal and prostate ca.
Positively
What is a phytochemical?
Chemical that protects plants against disease and bacterial or fungal infection (liek antioxidatns)
What role doe phytochemicals play in cancer?
may prevent tumor growth in humans
What foods are rich in phytochemicals?
plant based foods (fruits, veggies)...

grapes, apples, berries, green tea, red wine.

carotenois: carrots, tomatoes, spinach
What are the two main classes of plant phytochemicals?
carotenoids, flavenoids
What is soy's role in breast cancer?
several studies have shown that consumption of soy reduces women’s risk of developing breast cancer, especially in pre-menopausal women. … somewhat controversial
What is soy's role in prostate cancer?
- controversial: studies suggest reduced PSA with soy intake.
What berries are high in ellagic acid and anthocyanidins?
ellagic acid (may prevent cancer): raspberries, strawberries, pomegranites

anthocyanidids (most potent antioxidens ever - may stop cancer): raspberries, blueberries
What is cancer cachexia?
- loss of muscle mass, visceral protein, and body fat in cancer pts.

- weight loss >5% pre-morbid wieght in past month
Describe MNT for cancer patietns.
- maintain nutritional status during cancer treatment.
What are protein needs for cancer patients?
1-1.5 g/kg
Kcal nees in cancer patients are often ____.
Elevated
How much omega-3 FFA should be consumed?
2.1g/day
What are the two basic components of MNT for cancer pts?
1. maintain energy and protein intake
2. manage GI side effects
Should patients on chemo or radiation for cancer be given Multivitamin or individual vitamins?
No, vitamins contribute to cell growth and are contraindicated in radiation or chemotherapy.
When is EN needed?
- 100cm+ working small bowel
- oral intake not possible for 7-14 days or so
- contraindicated in peritonitis, obstruction, vomiting, diarrhea, ileus, ischemia or pt refusal.
When should a more permanent (than NG) feeding tube be placed?
- EN >4-6 weeks,
- tolerance problems
- when other abd. surgery is being done
WHat are the various feeding tube places?
- nasogastric, nasoduodenal, nasojejunal
- PEG or PEG in jejunum (PEG/J)
- surgical to stomach (g-tube) or jejunum (Jtube)
When is a jejunal tube placement indicated?
due to reflux, aspiration risks, tolerance problems
Describe dumping syndrome with regards to EN.
Too much carbohydrate results in the contents of teh gut being hypertonic and cells lining the gut dump all their water content into the gut to dilute it... results in abdominal cramping, nausea, and severe diarrhea.
What is residual with regards to EN?
amount of formula being held in the stomach - can be used as measure of tolerance by withdrawing and measuring it
Know how to calculate fluid needs/ flushes.
1. given fluid requireent, calculate total fluid needs by multiply x kg
2. subtract formula free water from total need
3. divide remainder by increments to establish q4h flushes....
How would you initiate continuous TF orders and advancement?
COntinuous: start at 30mL/hr, advance 20-30mL q 6-8h up to goal rate depending on tolerance
How do you establish a goal rate for continuous EN?
total volume needeed/ total # hrs
What is appropriate TF orders for intermittent or bolus feeding and advancement?
- initial rate of 150-200mL over 20-40 mins.
- advance by 50-100mL each feeding depending on tolerance and up to goal
How do you establish goal volume in intermittent feeding?
total volume needed/ #feedings
WHat is the osmolality of a EN formula for general purposes?
300-500
400-700 osmolality is considered ___ EN formula.
Nutrient dense
Give 1 example of formula for each:
- renal failure
- diabetic
- need for high cal
RF: Nepro
DM: Glucerna
Cal: Nutren
Describe how to prevent aspiration:
1. elevate head 30-40deg
2. monitor for content in lungs
3. monitor residuals
4. consider dual lumen tubes with poor gastric emptying
5. radiography
6. observation of pulled fluid from feeding tube.
7. check pH of fluid aspirated from tube (gastric vs abdominal)
8. monitor and maintain adequate airway cuff pressure
What is c-dif and who is at risk?
opportunistic GI infection due to bacteria overgrowth. Common in pt’s with recent abx treatment and inpatient hospital stays.
What is ASPEN?
American Society for Parenteral and Enteral Nutrition
When is PN indicated?
- nonfunctioning GI tract
- intractable vomiting
- ileus
-GI ischemia
- diffuse peritonitis
- unable to access GI tract
- duration of 7+ days
- venous access available.
Where is CPN given? PPN?
CPN: central vein such as subclavian

PPN: peripheral vein
When is CPN indicated?
- concentrated formula,
- long term
- >7days PN requirement
- elevated metabolic rate
- poor peripheral access
When is PPN indicated?
- dilute concentrations
- short term to give GI rest
- unable to obtain central access
What is the maximum osmolality that can be given via PPN?
900 mOsm/L
What are the main components of PN soultions? (3)
1. CHO
2. Protein
3. Lipids (IVFE)
What is the most common CHO in PN?
dextrose monohydrate
What is refeeding syndrome and who is at risk?
- If pt has not eaten for a while (risk) electrolytes, glucose, osmolality, etc can easily be thrown off by PN therapy. Risk = malnourished. Causes severe problems.
What would you try to do PRIOR to initiating PN in a pt at risk for refeeding syndrome?
- replace deficiencies as much as possible
How would you initiate PN in a pt at risk for refeeding syndrome?
Begin with goal proteins and lipids with low calories (25-50% goal) at normal goal rate.

Adcance q6-8 hours until goal cal reached

Start with 100-150 g CHO/ day, then work up.
What labs should be monitored to determine tolerance of PN?
1. glucose
2. BMP (electrolytes, Mg, Phos, pH)
3. TUN, prealbumin (PAB), CRP, BUN, ammonia
4. Triglycerides
5. liver function
6. vitamins
What labs are most likely to be abnormal in refeeding syndrome?
1. K+
2. Phos
3. Mg
4. Ca
Why would a person be hypokalemic in refeeding syndrome?
insulin forces extracellular K+ into cell
What ist he predominant feature of refeeding syndrome?
Hypophosphatemia (inc. anabolism = inc. phosphorylation)
What labs would you monitor for tolerance of protien in PN?
UUN, TUN, PAB, CRP, BUN, ammonia
What is the relationship between PAB and CRP?
?????
What labs would you monitor for tolerance of lipids in PN?
Triglycerides
When would you hold IVFE in PN?
Triglycerides >400
Glucose should be measured how often in PN?
4-6 h
What is the goal prior to initiating PN for glucose?
<300, if >180 keep at minimal dextrose concentration until corrected
What ist he goal for glucose values during PN?
100-150mg/dL
What rate should EN be at before reducing PN when transitioning to tube feeding?
15-20mL/hr

(keep total goals consistent between both)
What is the goal PO intake prior to d/c of PN when transitioning to oral intake?
60% of goal before stopping PN, minimum of 500kcal/day
What diet factors are recommended in pulmonary patients (COPD, Pulm fibrosis, etc)?
High calorie, high protein, modify textures as needed for ease of eating
Ptients with renal stones shoudl consume how much oxylate daily?
<40 to<50 mg/day
What is the difference between HD and PD?
HD= hemodialysis: 3-5 hrs long usually 3 days/week. BLood is pumped out of the body, through a filter, and back in...

PD = peritoneal dialysis: 10-12h/day 3x/week... solution is pumped into peritoneum, tonicity collects wastes in the fluid through the peritoneal membrane as a filter, and then is drained back out with wastes
Describe MNT considerations for dialysis pts: (4)
- protein equillibrium important, avoid excess weight gain
- Keep serum Na and K normalized
-Keep other serum electrolytes normalized to avoid osteodystrophy
- enable pt to eat palatble attractive diet that fits their lifestyle
What is important considering protein needs in dialysis pts?
needs increase when dialysis is initiated, it is measured by monitoring serum albumin and intake
What is adequate protein in HD, PD, CAPD?
HD: 1.2g/kg/day
PD: 1.2-1.3g/kg/Day
CAPD: may be more!
What formula should be checked to assure chance of calcification is low can be used when managing calcium and phos?
Serum calcium x serum phos should be less than 55.

Ca x Ph <55
What is the goal of iron levels in iron deficiency anemia due to CKD?
- iron sat >20%
- ferritin> 200ng/dL
When should you hold iron supplementation in CKD?
Ferritin >500
What vitamin should be avoided in supplementation with pts at risk for kidney stones?
Vitamin C (breaks down into oxalate acid)
How do you correct serum calcium?
correction factor x (nml alb- serum alb)

CF= 0.8
Nml alb = 4.0mg/dL
What are protein needs for pts with ARF and GFR<10?
-restrict to 0.8mg/kg if not on dialysis or catabolic.
- on PD: 1.2-1.3g/kg
-on HD: 1.2g/kg
When should protein intake be restricted in pts with ARF?
GFR<10, not catabolic, and not on dialysis
What are kcal needs in a pt with ARF?
35kcal/kg standard but depends on level of hypermetabolism (some only 20-30kcal/kg)
In ARF, which is better? Slight over feeding or slight underfeeding.
Under
What are the differnet stages of CKD and their associated GFRs?
stage 1: >90 (proteinuria)
Stage 2: 60-90 (mild damage)
stage 3: 30-59 (mod damage)
stage 4: 15-29
stage 5: <15
WHat is the MNT goal for predialysis? (stages 1-4)
- slow progression of ckd
- provide adequate kcal
- prevent uremia
- restore biochem, calci/phos, vitamins, and iron balance
What is the MNT suggestion for protein in CKD?
- control intake to avoid neg. nitrogen balance
- stage 1-3: 0.75g/kg/day
- stage 4-5: 0.6g/kg/day
**use ABW if needed**
What type of pts in CKD may protein restriction be contraindicated for?
Catabolic states
What is the MNT recommendation of kcal for CKD?
30-35kcal/kg/day
MNT for CKD regarding lipids is:
- MUFAS and PUFAS
- monitor lipid levels for common dyslipidemia
- keep serum lipids WNL
Sodium restrictions in CKD recommend how much?
<2.4g/day
What does MNT for CKD say regarding Potassium?
- restrict in later stages
- meds can elevate K+ levels
- restriction needed if levels >5 consistently
- restrict to 2-3g/day
Phosphorus restriction in CKD shoudl be:
- 800-1000mg/day
- if serum phos>4.6mg/dL
- may be difficult when trying to get adequate protein
MNT for calcium in CKD suggests:
1.5-2g/day stages 3-4, 1.5-1.8g/day in stages 4-5 not on dialysis
- caution with hyperparathyroidism that can lead to hypercalcemia
What is secondary hyperparathyroidsim?
Calcium levels drop too low (CKD) resulting in parathyroid glands prducing excess PTH.
What should be restricted, and how much, if PTH levels are too high?
- monitor calcium levels
-restrict phosphate to 800-1000mg/day
What foods are sources of potassium?
artichockes, beans, carrots, potatoes, spinach, tomato, bananas, cantaloupe, many many more (table 10-3)
WHat foods contain phosphorus?
cheese, dairy products, beef, whole eggs, liver, peanut butter, soybeans, (more on p 401 table 10-2)
Describe vitamin/iron needs for pts with CKD.
Folic acid:
Pyridoxine:
Ascorbic acid:
ETC
Folic: 1mg/day
Pyridoxine: 5mg/day
ascorbic: 60-100mg/day
- vitamin D also required due to poor kidney function
- do not supplement vitamin A
-iron supplementation may be needed, based on labs
What vitamin should not be supplemented for pts in CKD?
Vitamin A
What are examples of loop diuretics (or K+ wasting diuretics)?
furosemide, HCTZ = useful in later CKD when potassium is elevated and still need to shed water
What are examples of ptoassium sparing diuretics?
Spironolactone - may be used with K+ depleting diuretics to prevent too much K+ loss.