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177 Cards in this Set

  • Front
  • Back
• Lipid-
family of organic compounds soluble in organic solvents but not in water. They include triglycerides (fats and oils) phospholipids and sterols
• Cholesterol-
member of the group of lipids known as sterols; a soft waxy substance made in the body for a variety of purposes and also found in animal derived foods
• Fats-
lipids that are solid at room temperature (70 F or 25 C)
• Oils-
lipids that are liquids at room temperature (70 F or 25 C)
• Point of un-saturation-
a site in a molecule where the bonding is such that additional hydrogen atoms can easily be attached
• Unsaturated fatty acid-
a fatty acid that has one or more points of un-saturation. An unsaturated fat is a triglyceride that contains one or more unsaturated fatty acids
• Emulsifier-
a substance that mixes with both fat and water and permanently disperses the fat in the water, forming an emulsion
• Emulsification-
the process of mixing lipid with water by adding an emulsifier
• Bile-
an emulsifier made by the liver from cholesterol and stored in the gallbladder. It doesn’t digest fast as enzymes do but emulsifies it so that enzymes in the watery fluids may contact it and split the fatty acids from their glycerol for absorption
• Lipoproteins
-clusters of lipids associated with protein which serve as transport vehicles for lipids in blood and lymph. Major lipoprotein classes are the chylomicrons, VLDL LDL and HDL
• Chylomicrons
Chylomicrons transport food fats through the water body fluids to the liver and other tissues
transport in the lymph and blood
• Very low density lipoproteins (VLDL)-
lipoproteins that transport triglycerides and other lipids from the liver to various tissues in the body
• Low density lipoproteins (LDL)-
lipoproteins that transport lipids from the liver to other tissues such as muscle and fat; contain a large proportion of cholesterol
• High density lipoproteins (HDL)-
lipoproteins that return cholesterol from the tissues to the liver for dismantling and disposal; contain a large proportion of protein
• Oxidation-
interaction of a compound with oxygen; in this case, a damaging effect by a chemically reactive form of oxygen
• Dietary antioxidant-
a substance in food that decreases the damaging effects of reactive compounds such as reactive forms of oxygen and nitrogen on tissue functioning
• Linoleic acid and linolenic acid-
polyunsaturated fatty acids that are essential nutrients for human beings
• Omega-6 fatty acid-
and example
a polyunsaturated fatty acid with its endmost double bond 6 carbons from the end of the carbon chain. Linoleic acid is an example
• Omega-3 fatty acid-
a polyunsaturated fatty acid with its endmost double bond 3 carbons from the end of the carbon chain. Linolenic acid is an example
• Trans-fatty acids-
fatty acids with unusual shapes that can arise when hydrogens are added to the unsaturated fatty acids of polyunsaturated oils
• Hydrogenation-
process of adding hydrogen to unsaturated fatty acids to make fat more solid and resistant to the chemical change of oxidation
• Proteins-
compounds composed of carbon, hydrogen, oxygen, and nitrogen and arranged as strands of amino acids.
• Amino acids-
the building blocks of protein. Each has an amine group at one end, an acid group at the other, and a distinctive side chain
• Amine group-
the nitrogen containing portion of an amino acid.
• Side chain-
the unique chemical structure attached to the backbone of each amino acid that differentiates one amino acid from another.
• Essential amino acids-
amino acids that either cannot be synthesized by the body or cannot be synthesized in amounts sufficient to meet physiological need.
• Conditionally essential amino acid-
an amino acid that is normally nonessential but must be supplied by the diet in special circumstances when the need for it exceeds the body’s ability to produce it.
• Collagen-
a type of body protein from which connective tissues such as scars, tendons, ligaments, and the foundations of bones and teeth are made.
• Denaturation-
the irreversible change in a protein’s folded shape brought about by heat, acids, bases, alcohol, salts of heavy metals, or other agents.
• Protein turnover-
the continuous breakdown and synthesis of body proteins involving the recycling of amino acids.
• Antibodies-
large proteins of the blood, produced by the immune system in response to an invasion of the body by foreign substances (antigens). Antibodies combine with and inactivate the antigens.
• Edema-
swelling of body tissue caused by leakage of fluid from the blood vessels; seen in protein deficiency (among other conditions)
• Acids-
compounds that release hydrogens in a watery solution.
• Bases-
compounds that accept hydrogens from solutions.
• High quality proteins-
proteins containing all the essential amino acids in relatively the same amounts that human beings require.
• Limiting amino acids-
an essential amino acid that is present in dietary protein in an insufficient amount, thereby limiting the body’s ability to build protein.
• Complementary protein-
two or more proteins whose amino acid assortments complement each other in such a way that the essential amino acids missing from one are supplied by the other.
• Nitrogen balance-
the amount of nitrogen consumed compared with the amount excreted in a given time period.
• Protein energy malnutrition (PEM)-
the world’s most widespread malnutrition problem, including both marasumus and kwashiorkor and states in which they overlap
• Marasmus-
the calorie deficiency disease; starvation
• Kwashiorkor-
a disease related to protein malnutrition, with a set of recognizable symptoms, such as edema.
• Dysentery-
an infection of the digestive tract that causes diarrhea.
• Osteoporosis-
a disease of older persons characterized by porous and fragile bones that easily break, leading to pain, infirmity, and death
• Vitamins-
organic compounds that are vital to life and indispensable to body functions but are needed only in minute amounts, non-caloric, essential nutrients
• Precursors, pre-vitamins-
compounds that can be converted into active vitamins
• Beta-carotene-
an orange pigment antioxidant activity, a vitamin A precursor made by plants and stored in human fat tissue
• Epithelial tissue-
the layers of the body that serve as selective barriers to environmental factors. Examples are the cornea, the skin, the respiratory tract lining, and the lining of the digestive tract
• Cell differentiation-
process by which immature cells are stimulated to mature and gain the ability to perform functions characteristic of their cell type
• Dietary antioxidants-
compounds found in plant foods that significantly decrease the adverse effects of oxidation on living tissues. The major antioxidant vitamins are vitamin E, C, and beta carotene
• Rickets-
the vitamin-D deficiency disease in children; characterized by abnormal growth of bone and manifested in bowed legs or knock-knees, outward-bowed chest, and knobs on the ribs
• Osteomalacia-
the adult expression of vitamin D-deficiency disease, characterized by an overabundance of un-mineralized bone protein.
• Free radicals-
atoms or molecules with one or more unpaired electrons that make the atom or molecule unstable and highly reactive
• Jaundice-\
yellowing of the skin due to spillover of the bile pigment bilirubin from the liver into the general circulation
• Scurvy-
the vitamin C-deficiency disease
• Coenzyme-
a small molecule that works with an enzyme to promote the enzyme’s activity. Many coenzymes have B vitamins as part of their structure
• Beriberi-
the thiamin deficiency disease; characterized by loss of sensation in the hands and feet, muscular weakness, advancing paralysis, and abnormal heart action
• Pellagra-
the niacin-deficiency disease. Symptoms include the “4 Ds”: diarrhea, dermatitis, dementia, and ultimately, death
• Neural tube defects (NTD)-
abnormalities of the brain and spinal cord apparent at birth and believed to be related to a woman’s folate intake before and during pregnancy
• Intrinsic factor
-a factor found inside a system. The intrinsic factor necessary to prevent pernicious anemia is now known to be a compound that helps in the absorption of vitamin B12
• Pernicious anemia-
a vitamin B12 deficiency disease, caused by lack of intrinsic factor and characterized by large, immature red blood cells and damage to the nervous system
Function of fat
insulation, call reproduction, cushions and protects organs
Number of fatty acids, glycerols in Monoglycerides, Diglycerides, Triglycerides
Monoglycerides- 1 fatty acid, 1 glycerol
Diglycerides- 2 fatty acids, 1 glycerol
Triglycerides- 3 fatty acids, 1 glycerol
How do Fatty acids differ
chain length and degree of saturation
Classes of lipids
Sterols, phospholipids
Main sterol
cholesterol
Functions of cholesterol
made into bile, sex hormones, Vitamin D, emulsifier
important to structure of cell membranes, necessary to body function
function of Phospholipids
emulsifier, Makes a bubble around the fat
o Unsaturated fatty acid-
chain that possesses one or more points of unsaturation
• Lipid Digestion
o Nothing in mouth or stomach
o Small intestine- bile emulsifies, triglycerides break down, enzymes come from pancreas (makes fat digestion more efficient)
o Villi-
 takes short chain fatty acid into the blood, then liver
 long chain fatty acid, repackages them, goes into lymph, blood, then liver
o Large intestine- fiber grabs cholesterol and it is excreted in feces
Lipid absorption
o Cells extract lipids
Lipid transportation
oLarge chain fatty acid must form lipoproteins to go into lymph, blood, liver
oTriglycerides go to fat deposits in the body: muscles, breasts, and fat layer under the skin
Use of lipids in body
o Lipoproteins- lipid and protein molecules used for transportation in the lymph and blood (chylomicrons)
o Energy
• Health benefits of lipids
o Get essential fatty acids
o get HDL-lowers cholesterol
o fats aid in the absorption of phytochemicals
Importance of essential fatty acids
-Can prevent blood clots, stroke
-Lowers blood pressure, lowers risk for heart disease
-Helps form structures, good for the brain
• Health problems associated with lipids
o LDL takes cholesterol to the tissues
o Greater risk for heart disease, stroke, high blood pressure,
• Sources of cholesterol- saturated and trans fats
o Nutritious if used in moderation
o Animal products- eggs, beef, poultry, cheese, milk
• Sources of unsaturated fats
o Fish, oils, nuts, seeds
• Sources of saturated fats
o Meat, milk and added fats
• Purpose of hydrogenation
o Makes it a more stable structure, less likely to oxidize
o Longer shelf life
o Can change texture of food and its properties
o Cheap
• Drawbacks of hydrogenation
More saturated
Creates trans fatty acids
Increases LDL and lowers HDL
Changed shape
• Recommendations for fat intake: DRI, AMDR
o DRI: 30g/day, limit saturated and trans fats
o AMDR: 20-35%
o Cholesterol >300mg/day
• Fat replacers
o Conventional ingredients in unconventional ways
o Whip air in, use skim milk or water, use lean cuts of meat, etc.
o Choose natural foods
o Low/reduced fat foods
o Reduce fat intake
• Olestra problems
o Vitamin and phytochemical loss, possible digestive upset, anal leakage, slight aftertaste, expensive, no long term studies in children
• Structure of Proteins
o Proteins have nitrogen, unlike other macronutrients, have carbon, hydrogen and oxygen
o Proteins have a backbone – amine and acid groups, and a side chain that is different for all types of amino acids
• Amino Acids in body
o Body can only produce 10 types of amino acids for itself
o Some must come from food
o If the body doesn’t have a certain amino acid when it is forming a protein it will destroy the whole chain and recycle the amino acids
- A protein can contain 20 different amino acids
• Protein digestion
o Other than being crushed, torn by chewing, saliva, nothing happens until stomach
o Stomach-denatures protein, uncoils bonds-enzymes can attack peptide bonds
o Small intestine-
 proteins denatured fully, broken up into amino acids - polypeptides
-Enzymes from pancreas, intestines work until they’re in single amino acids-tripeptides
• Protein absorption
o Small intestine absorbs single amino acids
- Enzymes on surface split up di and tri peptides
- Some absorbed large then split
- Most don’t stay intact when entering bloodstream
o Amino acids- bloodstream -> liver -> used or released into blood for other cells
• Nitrogen balance
o Healthy adults-protein in=protein out; equilibrium
o Positive nitrogen balance-growing child, person building muscle, pregnant woman; retain more nitrogen than excreting
o Negative nitrogen balance-astronaut, surgery patient; lose more nitrogen than taking in
• Roles of Protein
o Makes structures-muscles, hair bones, cells
o Regulation-hormones, enzymes (turn on/off body processes)
o Energy-4 cal/gram
• Different Protein qualities, food sources
o High quality-animal products—milk, meat
o Mid range—legumes
o Low range—grains (absorb about 70-90%)
• Complementary proteins examples
o Grains/nuts + legumes
o Tortillas + beans
o Rice + lentils
o Pita bread + hummus
o Bread + peanut butter
How can one recognize saturated fats?
solid at room temperature
Which is not a health benefit associated with more dietary fats coming from omega-3 than omega-6 sources?
Longer endurance during exercise
What does hydrogenation do to fatty acids?
It makes them resistant to oxidation.
What is not characteristic of the traditional heart healthy Mediterranean diet?
coconut oil
Which is NOT part of the recommendations for fat intake?
Add more poly- and mono-unsaturated fats to the diet if it is high in saturated fats
What makes up a triglyceride?
A glycerol molecule with three fatty acids
Are amino acid supplements more easily digested than whole proteins?
no, whole proteins are more easily digested
Which part of amino acids is excreted in urine?
Nitrogen
When does negative nitrogen balance occur?
When muscle is broken down and lost
What food group has high quality protein?
animal products--milk, meat
Which is true about complementary proteins?
They provide all the essential amino acids.
What isn't associated with excess of proteins?
enlarged livers in humans
How does a child with marasmus look?
A child with marasmus is starving and looks like skin and bones.
Which is NOT one of the main ideas in the article, "A New Food Guide for North American Vegetarians"?
Vegetarians need to follow a very strict food guide in order to meet nutrient needs.
All of these are examples of "looking beyond the mark," EXCEPT for:
Following the counsel of the Brethren.
What could vegetarians consume to include B12 in their diets?
fortified non dairy milk
Which is true concerning fat soluble vitamins?
They are stored in the liver and fatty tissues and do not need to be supplied every day.
Which vitamin can the body make?
Vitamin D
The best natural sources of Folate include:
Raw spinach
Main function of vitamin K is
help synthesize proteins that clot the blood
Which is not a good source of vitamin A or beta carotene
grains
Which vitamin can be synthesized by bacteria found in the digestive tract
vitamin K
Why is milk sold in opaque plastic containers?
Plastic containers protect riboflavin from being destroyed by UV light
Who would be most likely to develop pellagra?
A person who does not consume meats and eats corn as the dietary staple
In the US scurvy is seldom seen today except in:
People addicted to alcohol
Beriberi is a deficiency of which vitamin?
thiamin
Women taking vitamin supplements over several years to help with PMS symptoms developed problems with numbness in their hands and feet and were then unable to walk. Which vitamin in the supplement was most likely to cause the symptoms?
Vitamin B6
Which best maintains the vitamin and mineral contents?
Cook vegetables in a small amount of water for the least amount of time possible.
How can nutrient supplements be dangerous to overall health?
They can interfere with the use of other vitamins.
Who would be most likely to develop pellagra?
a person who doesn't consume meats, consumes corn as a dietary staple
Which supplement would be best?
supplement with less than the DRI of every nutrient for you gender, age
AMDR, RDA for protein
• AMDR: 10-35%
• RDA: .8 g/kg (of body weight) /day
Protein deficiency
o Marasmus-commonly among children 6-18 months,
o Kwashiorkor-mostly in countries where a baby is weaned from breast milk when a second baby is born
Symptoms of marasmus
-muscles waste and weaken
-brain development is stunted, learning impaired
-body temperature low, skin cracks,
Symptoms of kwashiorkor
- High protein->low protein
- Fluids out of blood -> belly and legs ->edema
- No melanin-hair loses color, patchy and scaly skin, unhealed sores and measles
• Excess protein
o Heart disease, kidney disease, adult bone loss, cancer
• Benefits of vegetarian diets
o Less obesity/ chronic disease
• Pitfalls of vegetarian diets
o Low energy for kids, less minerals
o Concerned about: vitamin B12, vitamin D, mineral: calcium
Characteristics of vitamins
• Essential, non-caloric, organic nutrient needed in small amounts in the diet
• Role of vitamins
help make possible processes by which other nutrients are digested, absorbed, and metabolized or built into body structures
• Fat soluble vitamins characteristics
o Found in fats and oils of foods, require bile for absorption
o Stored in liver and fatty tissues—don’t need to eat daily
• Water soluble vitamins characteristics
o Absorbed directly into the blood stream, travel freely
o Excesses excreted in urine, risks of toxicities not as great
o Needed in frequent doses (1-3 days) since not stored
• Functions of Vitamin A-
Regulation of gene expression, eyesight, skin and body linings, growth, immunity
• Vitamin D function-
Maintain blood calcium level, raise absorption of calcium (small intestine), regulate excretion of calcium (kidneys), strengthen bones
• Vitamin E function-
Antioxidant, stabilize free radicals, stops chain reaction, donates electron to stabilize
• Vitamin K function
Blood clotting proteins, bone matrix protein formations
• Vitamin C function
Connective tissue-collagen, antioxidant
• B vitamins function
o Involved with energy metabolism, act as coenzymes
o B12, Folate-DNA and RNA synthesis
o B12-maintain nerve cell integrity
o B6-helps convert tryptophan to niacin
• Vitamin A food sources
orange foods (carrots, sweet potato, apricot, cantaloupe), (dark) green foods (bok choy, spinach), milk, beef liver
• Vitamin D sources
sun exposure, seafood, milk
o Interference- sunscreen, concealing or heavy clothes, smog, makeup, high or low latitudes, window glass and screens, clouds, smoke,
• Vitamin E sources
vegetables oils and products: safflower oil, canola oil, margarine, salad dressings, mayo; wheat germ, sunflower seeds
o Enhances blood thinners (in toxic amounts) uncontrolled bleeding
• Vitamin K sources
cabbage, cauliflower, canola oil, spinach, lettuce and soybeans
• Vitamin C sources
citrus fruits: grapefruit, oranges; peppers, Brussels sprouts, broccoli, sweet potato, bok choy
o Thiamin sources
whole grains and enriched breads, pastas, cereals, etc; pork chop, sunflower seeds, green peas, potatoes, black beans
o Riboflavin sources
milk, yogurt, cheese, liver, pork, mushrooms, cereal
- UV light and irradiation- clear containers
o Niacin sources
meat products: chicken, pork, tuna; enriched cereal, potato, mushrooms
o Folate sources
green leafy vegetables- foliage: spinach; enriched cereal, beets, avocado, asparagus, pinto beans, beef liver, lentils
o B12 sources
meat products, milk products; in plant foods it is inactive
o B6 food sources-
liver, potato, chicken, bananas, sweet potato, spinach
• Vitamin A deficiency
impaired ability to see in dim light, outer covering of eye dries and hardens  infection, blindness; impaired cell differentiation: goblet cells in GI tract become misshapen, can’t function
• Vitamin D deficiency
disease: rickets- malformation of bones (children), osteomalacia- softening of bones, can lead to bone loss and osteoporosis (adults)
• Vitamin E deficiency
rare, no diseases
• Vitamin K deficiency
hemorrhaging- loss of blood, abnormal bone formation
• Vitamin C deficiency
disease: scurvy- bleeding gums, pinpoint hemorrhages; collagen problems, ruptured capillaries, slow wound healing
o Thiamin deficiency
disease: beriberi, symptoms: weakness and edema
o Niacin deficiency
disease: pellagra, symptoms: 4 d’s: diarrhea, dermatitis, dementia, death
Folate deficiency
- birth defect: spina bifida, damage, paralysis; anemia
o B12 deficiency
disease: (megaloblastic) anemia, cells can’t divide, folate can mask a B12 deficiency
o B6 deficiency
symptoms: weakness, depression, confusion, irritability, insomnia
• Vitamin A toxicity
get sick, birth defects in pregnant women, hypercarotenemia (not harmful)
• Vitamin D toxicity
not from over exposure to sunlight; acute symptoms, long term symptoms: from huge amounts of supplements- calcification of soft tissue, kidney stones
• Vitamin E toxicity
anticoagulant medicine= uncontrolled bleeding
• Vitamin K toxicity
opposes the effects of anti-clotting medicine
• Vitamin C toxicity
not commonly seen, but can happen >3g; urinated out, nausea, diarrhea, kidney stones
o B6 deficiency
nerve damage
Minimize nutrient losses
• Put most fruits and vegetables in the fridge – slows down breakdown of vitamins
• Protect it from light and air
o Opaque containers protects riboflavin
o Store cut fruits and vegetables in the refrigerator in sealed containers
• Minimize time exposed to water
o Avoid high temperatures and long cooking times
• Microwaving, steaming and stir frying for a short time is okay
• Who may need supplements:
o Pregnant/lactating women, or women who are able to get pregnant
o Newborns and Infants
o Lactose intolerant people
o Habitual dieters
o Old people
o Victims of AIDS or other wasting illnesses
o Druggies and alcoholics
o Those recovering from surgery, burns, injury, or illness
o Vegetarians and vegans
o People taking medications that interfere with the body’s use of nutrients
• Supplement pros
o Can prevent or reverse illnesses
o Good for people who have a condition that interferes with a person’s appetite, ability to eat, or ability to absorb or use nutrients
o People with deficiencies
o People with increased nutrient needs
o People with low nutrient status
o People coping with physical stress
• Supplement Cons
o Greater risk of nutrient imbalances or toxicities
o Toxicity- little kids think that it is candy
 Mild overdoses can make you sick, severe overdoses – death
o Life-threatening misinformation
 Can be misleading
o Unknown needs
 What nutrients and how much?
o False sense of security
 Consumers thinking supplements will cure diseases and cover needs
 Self-diagnosis
o Absorption and metabolism of nutrients
- Body absorbs nutrients best from foods
- Vitamin c enhances iron absorption
- Vitamin A can interfere with vitamin E metabolism
• How to choose good supplements
o Avoid supplements with extras like herbs
o Look for USF symbol on the label – will digest
o Vitamin C can erode tooth enamel
o Avoid vitamin bubble gum – kids can overdose
o Choose amounts smaller than, equal to, or very close to the intake recommendations
o Expect to reject about 80% of supplements
o Avoid! in supplements
- High doses of iron >10mg
- High doses of biotin
- Organic or natural
- High-potency or therapeutic dose
- Ones that have “new” nutrients
- Time release
- Stress formulas
-Pills with extracts of alalfa, berries, parsley, or other f’s and v’s
- Tonics
- With claims that today’s foods lack sufficient nutrients to support health
o B12, Folate function
-DNA and RNA synthesis
o B6 function
o B6-helps convert tryptophan to niacin
o B12 function
o B12-maintain nerve cell integrity
disease with 4 d's
pellagra
4 d’s:
diarrhea, dermatitis, dementia, death