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69 Cards in this Set

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Lipids

*30-35% of kcal intakeof American diet


*9kcal/gram


Fatty Acids

-come in different lengths and different numbers of double bonds


-usually bind to glycerol to form a tryglyceride

Tryglocerides

95% of dietary lipids


-contain 1 glycerol and 3 fatty acid per molecule


16 carbons saturated


double bonds

palmatic acid

18 carbons saturated


no double bonds

stearic acid

18 carbon monosacturated


1 doubl bond


found in olive oil

oleic acid

solid at room temperature


PALMITATE


red meat

saturated

liquid at room temperature


OLEIC ACID


olive oil

monosacturated

more than one double bond

polysacturated

medium chain found in dairy


increased blood LDL cholesterol

saturated fatty acids

(n-6) in canola oil


makes arachidonic acid (J&H)

Linoleic Polyunsacturated

(n-3) in flax seed oil & fish oil


makes EPA & DHA

Linolenic Polyunsacturated

We cannot make these polyunsacturated fats in our body and hey are essential

Linoleic and linolenic

Omega 6 Linoleic acid (18:2 w-6) can be made into ____

Arachidonic acid (20:4) J&H fatty acid

Omega 3 linolenic acid (18:3 w-3) can be made into ___

EPA and DHA

are used to make lipid droplets smaller and solubilize lipids

Bile and Bile acids

membrane composition is important so____

that signaling receptors work properly

Arachidonic Acid

-comes from polyunsacturated Omega 6


- is needed in the brain


-too much is bad

1. Damaged Cells


A signal in to activate A2 is sent when____ and this enzyme starts to break down PLs in the membrane.

there is a high amount od Arachidonic Acid in Phospholipids (PLs) and the cell is damaged

2.Damaged Cells


Activating A2 produces free arachidonic acid fatty acid molecules which convert to _____

Eicosanoid signaling molecules

3.Damaged Cells


cause pain, stimulate immune cells, cause platelets to clot and signal all sorts of repair mechanisms

Eicosanoids

4.Damaged Cells


inhibits Phospholipase A2 and slows release of arachidonic acid (decreasing inflamation)

Cortisone

Diseases known to be related to inflammatory responses

coronary artery disease


Inflammatory Bowl Syndrome Disease


asthma


Osteoporosis


Alzheimer's Disease


____ (desinflamatorio) anti-inflammatory

Omega 3 fatty acids (one gram per day

Three main coronary arteries

the right coronary artery


left anterior decending (LAD) coronary artery


circumflux coronary artery

1.Heart Attack


When LDL particles enter the sub endothedial space (heart) and gets stuck in there. Immune cells called ___ make particles into foam cells.

Macrophages

2. Heart Attack


Then the sub endothedial space becomes full with ___. Smooth muscle cells start dividing and pushing out ____. Heart attack can occur with a ___ blockage.

lipids


the lumen of the artery


50-60%

BMI

Body Max Index

____is made up of 3 energy consumptions: ____ , energy spent in ___ , ___ of digestion of food.

(TEE)Total energy Expenditure


1. BMR


2. in movement


3. thermic effect

% of energy consumption:


BMR ___

60%

% of energy consumption:


Activities and energy/movement ____

40%

60% BMR Used:


Brain ___

20%

60% BMR Used:


Kidneys____

5%



60% BMR Used:


Liver ___

20%

60% BMR Used:


Muscle ___

20%

60% BMR Used:


Adipose __

3%

60% BMR Used:


Other tissue ____

22%

BMR

Basal Metabolic Rate

LDL

low density protein that

PUFAS

Polyunsaturated fatty acids


A fatty acid that lacks four or more hydrogen atoms and has two or more double bonds between carbons -- for example, linoleic acid (two double bonds) and linolenic acid (three double bonds).

Saturated fatty aciDS

A fatty acid carrying the maximum possible number of hydrogen atoms -- for example, stearic acid.

HDL

The type of lipoprotein that transports cholesterol back to the liver from the cells; composed primarily of protein.

VLDL

The type of lipoprotein made primarily by liver cells to transport lipids to various tissues in the body; composed primarily of tryglycerides.

Monoglycerides

Molecules of glycerol with one fatty acid attached. A molecule of glycerol with two fatty acids attached is a diglyceride.

Monunsaturated fatty acid

A fatty acid that lacks two hydrogen atoms and has one double bond between carbons

Docosahexaenoic Acid (DHA)



An omega-3 polyunsaturated fatty acid with 22 carbons and six double bonds; present in fish and synthesized in limited amounts in the body from linolenic acid.


Derivatives of 20-carbon fatty acids; biologically active compounds that help to regulate blood pressure, blood clotting, and other body functions. They include prostaglandins, thromboxanes, and leukotrienes.

eicosanoids

A nitrogen-containing compound found in foods and made in the body from the amino acid methionine.

choline

Oxidation

The process of a substance combining with oxygen; oxidation reactions involve the loss of electrons

lipoproteins

Clusters of lipids associated with proteins that serve as transport vehicles for lipids in the lymph and blood.

Adipose tissue

The body's fat tissue; consists of masses of triglyceride-storing cells.

Eicosapentaenoic (EPA)

An omega-3 polyunsaturated fatty acid with 20 carbons and five double bonds; present in fish and synthesized in limited amounts in the body from linolenic acid.

Glycerol

An alcohol composed of a three-carbon chain, which can serve as the backbone for a triglyceride.

Chylomicrons

The class of lipoproteins that transport lipids from the intestinal cells to the rest of the body.

Cholesterol

One of the sterols containing four carbon ring structures with a carbon side chain.

Unsaturated fatty acid

A fatty acid that lacks hydrogen atoms and has at least one double bond between carbons (includes monounsaturated and polyunsaturated fatty acids).

Lipids

A family of compounds that includes triglycerides, phopholipids, and sterols.

Sterols

Compounds containing four carbon ring structures with any of a variety of side chains attached.

Point of unsaturation

The double bond of a fatty acid, where hydrogen atoms can easily be added to the structure.

Triglycerides


The chief form of fat in the diet and the major storage form of fat in the body; composed of a molecule of glycerol with 3 fatty acids attached; also called triacylglycerols.

Trans-fatty acids

Fatty acids with hydrogens on opposite sides of the double bond.



A chemical process by which by which hydrogens are added to monounsaturated or polyunsaturated fatty acids to reduce the number of double bonds, making the fats more saturated (solid) and more resistant to oxidation (protecting against rancidity).



prodices trans-fatty acids


Hydrogenation

What process are hydrolysis reactions a major part of?

Process of digestion

What percent of body fat is gluconeogenesis?

5%

Ketone bodies

product of the incomplete breakdown of fat that occurs in gluconeogenesis when glucose is not available

Ketosis

fat fragments combine with ketone bodies which accumulate in blood making it more acidic

Homeostasis?

maintenance of constant internal conditions by the body's control systems

Where is the major site of lipid digestion/hydrolysis?

small intestine

the presence of un-coupler proteins that allow hydrogens to leak through the inner membranes of the mitochondria and lowers the amount of ATP formed for the same amount of substrate burned.

phenomena of the skinny