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83 Cards in this Set

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Thiamin B Vitamin name and coenzyme
B1, TPP (thiamin pyrophosphate)
Riboflavin B Vitamin name and coenzyme
B2,
FAD-Flavin adenine dinucleotide
FMN-flavin mononucleotide
Niacin B vitamin name and coenzyme
B3,
NAD: nicotinamide adenine dinucleotide

NADP: nicotinamide adenine phosphate
Niacins other names
Nicotinic acid, nicotinamide
Precursor to niacin
tryptophan
pantothenic acid B Vitamin name and coenzyme
Vitamin B5, coenzyme A (CoA)
B6 AKA
pyridoxine, pyridoxal, pyridoxamine
B6 coenzyme
PLP pyridoxal phosphate
B12 is also known as
cobalamin
B12 coenzyme
methylcobalamin
Folate aka folic acid or folacin- COENZYME?
THF tetrahydrofolate
biotin coenzyme?
has none bitch!
Viatmin C is also known as?
Ascorbic acid and has no coenzyme
B1 major functions
(Thiamin) coenzyme involved in decarboxylation events in energy metabolism:
pyruvate->acetylCoA
B2 major functions
(Riboflavin) "hydrogen carriers" cofactors for enzyme complexes that transfer hyrogens during energy metabolism:
Krebs Cycle..
ETC..
fat breakdown
B3 Major Functions
(Niacin) "hydrogen carriers" involved in hydrogen transfers in energy metabolism:
glycolysis,
Kreb Cycle,
electron TC,
fat breakdown,
and fat synthesis
Tryptophan is the precursor to
NIACINNN!!!!! (:
Pantothenic acid major functions
(B5) component of acetyl CoA compd that plays a central role in energy metabolism
B6 major functions
protein metabolism =
transaminases/deaminases

neurotransmitter synthesis=
serotonin, norepinephrine, hemoglobin synthesis
B12 AKA COBLAMIN major functions
helps free folate by removing CH3 (which inturn activates the B12) nerve myelin formation, RBC formation, & DNA synthesis
Folate major functions
Carrier of 1 C units synthesis of RNA and DNA amino acid synthesis and many other functions
prevents neural tube defects in pregnancys
Biotin major functions
cofactor for enzymes that transport CO2, fat synthesis, glucogenesis,
Vitamin C major functions
antioxidant, collagen synthesis (collagen=pimp)
aa->neurotransmitters, role in IRS
Cholines major functions...
needed for synthesis of neurotransmitter acetylCHOLINE (get it) structural membrane phospholipids and signaling phospholipids
Deficiency symptoms of Thiamin (B1)
BERI BERI: polyneuritis: weaken heart muscle, GI disorders
Deficiency of Riboflavin (B2)
ariboflavinosis: GI disturbances, headaches, mental depression, dermatitis, cheilosis, photophobia
NIACIN deficiency
pellegra: dermatitis, diarrhea, delerium, dementia, death.

niacin deficiency = 4 D's
Pantothenic Acid deficiency symptoms..
nONE nope NONE
B6 Deficiency symptoms
RaRE: vague symptoms, headaches, dermatitis
B12 Deficiency symptoms...
pernicious anemia (oh my thats pernicious!) AKA megaloblastic anemia nerve dysfunction->paralysis
->permanent nerve damage
folate deficiency symptoms
megaloblastic anemia: GI tract disorders: 18-26 days after conception may cause neural tube defects
biotin deficiency symptoms
rare: fatigue, insomnia, lack of appetite
Vitamic C deficiency symptoms...
scurvy!! arrgh!!
pour wound healing, increased infections, bleeding, muscle degeneration, death, severe cardiac arrest and internal bleeding
Choline
rare: liver damage
Dietary Sources of thiamin
pork; enriched grains
Dietary sources of riboflavin
milk; milk products, enriched grains, liver
Dietary Sources of Niacin
meat, poultry, enriched grains
Dietary Sources of pantothenic acid
widely distributed meats, whole grain cereals
Dietary Sources of B6
meat poultry, fish, potatoes, spinach, bananas
Dietary Sources of B12
meat especially Liver
Dietary Sources of folate
legumes, green leafy veggies
dietary sources of biotin
liver, egg yolk, soy flour
dietary sources o Vitamin C...
orange, broccoli, green peppers, cantaloupe, grapefruit, cauliflower, strawberries.
dietary sources of choline...
liver, milk, eggs, peanuts
Name the water soluble vitamins with no toxicity ..
Thiamin, Riboflavin, Pantothenic Acid, biotin, choline is roare
Niacin toxicity level
>35mg nicotinic acid hot flashed, vomiting.
B6 toxicity level
prolonged use of more than 100mg may destroy nerves.
folate toxicity level..
>1 mg masks B12 deficiency induced pernicious anemia
Vitamin C toxicity level..
2g=upper limit... excess may cause diarrhea and kidney and bladder stoned; altered medical tests.
pre cursor to vitamin A
beta carotene
Other names for vitamin A
retinol, retinal, retinoic acid
Vitamin A daily intake recommendations
Men - 900 ug RAE/Day
Women - 700 ug RAE/day
Vitamin A Deficiency symptoms...
Hypovitaminosis, night blindness, corneal drying, triangular gray spots on the eye
Vitamin A Functions..
visions, maintenance of cornea, epithelial cells,
mucous membranes,
skin, bone and tooth growth, reproduction, immune system
Overdose and Upper Limit Intake
Hypervitaminosis A
Upper level: 3000 mg/day
Sources of Vitamin A...
retinol: fortified milk, cheese, cream, butter, fortified margarine, eggs, liver,

beta-carotene: spinah and other dark green leafy greens, orange fruits and veggies
Vitamin D is also known as
calciferol, 1.25 dihydroxy Vitamin D
animal version of Vitamin D
D3 or enderalciferol
plant version of Vitamin D
D2 or ergocalciferol
Functions of Vitamin D..
Mineralization of bones-
raises blood calcium and phosphorous by increasing absorption from digestive tract withdrawing calcium from bones, stimulating retention by kidneys.
Vitamin D Recommendations...
Adults
19-50 yrs: 5ug/day
51-70 yrs: 10ug/day
>70 yrs: 15ug/day
Vitamin D upper level:
50 ug/day
Vitamin D deficiency..
Rickets in Children
Inadequate calcification-bowed legs
deformed ribs
Osteomalacia and Osteoporosis...
Loss of calcium resulting in flexible soft bones
Overdose of Vitamin D
Hypervitaminosis D:
symptoms of Vitamin D overdose
elevated blood calcium, calcification of soft blood vessels, kidneys, heart, lungs, tissues
Sources of vitamin D..
synthesized in the body from sunshine:

or milk, margarine, butter, juices, cereals, and chocolate, mixes, veal, beef egg yolks
Fat soluble vitamins are..
Vitamin A, D, E, K
water soluble vitamins are..
Thiamin (B1), Riboflavin (B2), Niacin (B3), Pantholic acid, folate, Biotin, Choline B6, B12,
Vitamin E also known as..
Alpha-tocopherol
Functions of vitamin E..
Antioxidant
Stabilization of cell membranes..
regulation of oxidation's reactions, protection of polyunsaturated fatty acids (PUFA) and Vitamin A
Recommendations of Vitamin E..
Adults 15mg/day
Vitamin E upper level for adults
1000mg/day
Vitamin E Deficiency..
Red blood cell breakage, nerve damage
Vitamin E overdose.
Augments the effects of anti-clotting medication
Sources of Vitamin E
Polyunsaturated plant oils, leafy green vegetables, wheat germ, liver, egg yolks
Is vitamin E easily destroyed by heat and what..
heat and oxygen.
Vitamin K Definitions..
Phyloquinone,
Menaquinone,
Menadione,
Naphythoquinone,
Functions of vitamin K..
synthesis of blood clotting proteins and bone proteins
Recommendations for Vitamin K..
Men 120ug/day
Women: 90ug/day
Vitamin K Deficiency..
Hemorrhaging
Sources for vitamin K
Bacterial synthesis in the digestive tract, liver, leafy green veggies, cabbage type, milk
Overdose of Vitamin K and upper limit
none known