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83 Cards in this Set
- Front
- Back
difference between major minerals and trace minerals
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body requires at least 100 mg or more each day for major minerals and less than that for trace minerals
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bone turnover
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process bones go through of breaking down and rebuilding
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osteoclasts
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large cells that breakdown bone by producing acids and enzymes
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what are bones composed of
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a soft framework and minerals which make the bone hard
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what is the soft framework of bones made out of
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collagen and mucopolysaccharide (clear, cement substance)
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mineral component of bones
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mostly made of calcium and phosphorous (which makes the bone hard and gives it it's white color)
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rickets
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caused by calcium deficiency. also can be caused by low levels of vitamin D which causes calcium levels to drop. Only occurs in children
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osteomalacia
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calcium deficiency in adults similar to rickets that can also be caused by vitamin D deficiency
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osteoporosis
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low calcium intake for a long time which leads to porous bones
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how are bones different in osteoporosis and osteomalacia
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in osteomalacia, the bone is soft because there is little calcium in the bone, which is one of the main hardening elements in the bone.
in osteoporosis, the bone is brittle. the mineral content of the bone is the same, but there is less bone so it is weak |
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what other roles does calcium play in the body
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blood clotting,
transmission of neurotransmitters, muscle contraction, blood pressure modulation |
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what two hormones maintain calcium levels and how do they do so
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calcitonin is released from the thyroid gland and when calcium levels are rising (after a meal). stimulates calcium uptake in bones.
parathyroid hormone is released from the parathyroid gland when blood calcium levels fall and stimulates osteoclasts to dissolve bone and release calcium into blood |
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what is one thing to consider when taking too much calcium (calcium supplements)
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it can inhibit the absorption of other minerals such as phosphorous, iron, zinc, and magnesium
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food sources of calcium
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milk, dairy products, sardines, salmon, oysters, barley, cornmeal, almonds, broccoli, fortified foods
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what other things can interfere with the absorption of calcium
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oxalic acid (in spinach, beet greens, rhubarb), phytic acid, vitamin D deficiency
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what increases calcium excretion
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high protein and sodium levels
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function of phosphorous
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mostly found in bone, but also important for energy production and energy storage and for phospholipid bilayer
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food sources of phosphorous
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meats, poultry, seafood, eggs, milk, dairy, nuts, seeds, cereal grains, baked goods
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minerals that function as electrolytes
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sodium and potassium
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where is potassium usually found? where is sodium usually found? (inside or outside cell)
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potassium- intracellular
sodium- extracellular |
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functions of sodium and potassium
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fluid balance, acid base balance, nerve impulse activity, muscle contraction
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sodium deficiency can be caused by
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excessive sweating, vomiting, excessive diarrhea
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sodium deficiency leads to
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nausea, dizziness, muscle cramps
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what hormone is used to regulate sodium
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aldosterone released from adrenal glands. regulates reabsorption of sodium and water from the kidney tubule
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salt sensitive
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a reduction or increase in salt intake can cause a large change in blood pressure
about 30% of adults with normal blood pressure and 50% of adults with high blood pressure are salt sensitive |
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what is potassium important for that sodium isn't
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heart activity.
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sodium vs. potassium absorption
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sodium and potassium compete for absorption and high levels of one, inhibits absorption of the other. most people in america have high levels of sodium, and low levels of potassium
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potassium deficiency is related to
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increased blood pressure and abnormal heart activity
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food sources of potassium
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leafy and other vegetables, whole grains, potatoes, bananas, avocado, cantaloupe, oranges, beans
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where is magnesium found
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in bone, and intracellular. about 1% is extracellular
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role of magnesium in the body
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cofactor for many enzymes and important for ATP formation, involved with muscle, important for normal functioning of heart
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magnesium deficiency
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may lead to heart attacks, muscle weakness, cramping, tetany (muscle twitching), irregular heartbeat
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what factors might lead to magnesium deficiency
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diuretics, alcohol, long standing diarrhea or vomiting
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magnesium in processed foods
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refining wheat gets rid of most magnesium so diets high in processed foods have low magnesium levels
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excess magnesium can lead to
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severe diarrhea, muscle relaxation (heart failure), calcium antagonist
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food sources of magnesium
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whole grains, wheat bran, nuts and legumes, green leafy vegetables, seafood
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where is chloride found in the body
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in extracellular fluid (with sodium)
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function of chloride in body
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water balance, acid-base balance, extracellular fluid in NS, HCL in stomach acid
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food sources with chloride
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meats, milk, eggs, processed food
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where does sulfur come from in the diet
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protein
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how long can adults and children live without water
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adults=10
children=5 |
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functions of water
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carries nutrients throughout body, solvent for substances in the body, maintains blood volume, temperature regulation, removal of waste products, lubrication of joints, shock absorber
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where does most water content come from in food
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mostly fruits, vegetables, meats. About 20-30% of water intake comes from food
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what part of brain monitors water metabolism
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hypothalamus
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how does the hypothalamus monitor water levels
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it releases antidiuretic hormone from the posteroir pituitary which causes kidneys to conserve water and decrease urination. also increases thirst
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difference between hard water and soft water
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hard water is high in calcium and magnesium, soft water is high in sodium
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functions of iron
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important for the reactions involved in making ATP, part of hemoglobin, part of myglobin (O2 storage)
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what is the most common nutrient deficiency worldwide
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iron deficiency
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iron deficiency symptoms
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fatigue (because energy metabolism needs iron to work efficiently, and because less oxygen is being transported to cells which need oxygen for efficient energy metabolism) and disruption in immune system,
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anemia symptoms (longterm iron deficiency)
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fatigue, paleness, poor temperature regulation, impaired ability to do work (mental and physical), impaired immune system
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microcytic
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small RBC's- seen in anemia
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hypochromic
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pale red color seen in RBCs of anemic patients due to loss of hemoglobin
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different types of iron consumed from meat and vegetables
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heme iron is found in meat and it is absorbed better. non heme iron is found in vegetables and it's absorption can be increased through vitamin C
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what things can interfere with absorption of iron
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high intakes of calcium, phytic acid and oxalic acid, high intake of tannins in tea and coffee
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siderosis
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excess iron accumulation in tissues, can lead to damaged liver and pancreas because iron accumulates in it
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hemochromatosis
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hereditary condition that leads to increased absorption of iron in food. since iron isn't being excreted, this disorder is treated through regular blood drawings
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zinc functions
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it is frequently used as a cofactor for enzymes used in synthesis of skin protein and DNA synthesis.
However, it is also used in the immune system and as an antioxidant. In the pituitary, it is needed to release gonadotrophin and growth hormone |
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zinc and unleavened bread
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when there isn't yeast in bread, the phytic acid binds to zinc and makes it unable to be absorbed. when zinc is present, it separates the phytic acid leaving the zinc available again.
This lead to iron deficiency in Egypt and Iran which lead to poor growth and delayed sexual development |
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besides delayed sexual development and growth, what are some other effects of zinc deficiency
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zinc is important for the maintenance of taste buds, so a lack of taste.
zinc is also involved in the synthesis of new skin, so poor wound healing zinc plays a role in immunity so decreased immunity |
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where is most of the iodine found in the body
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thyroid gland. this is because it is part of the thyroid hormone which regulates basal metabolism
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goiter
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caused by iodine deficiency. this is a painless lump in the neck that people get that sometimes grow so large that it puts pressure on the trachea.
it is frequently associated with hypothyroidism (characterized by decreased BMR, lethargy, gaining weight, and feeling cold) |
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cretinism
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occurs in infants if mother has iodine deficiency. symptoms include mental deficiency and shortened stature.
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how can someone increase their iodine intake
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eating plants from a variety of regions (different areas have different mineral content in soil that ends up in plants), eating iodized salt,
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goitrogens
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substances that interfere with iodine in the body
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toxic goiter
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when iron levels are too high
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selenium functions
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antioxidant (through interaction with vitamin E and the enzyme glutathione peroxidase)
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glutathione peroxidase
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enzyme with four molecules of selenium and works as part of the antioxidant defense network
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selenium deficiency
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heart muscle disease and white muscle disease
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selenium toxicity
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gingivitis, cirrhosis of the liver, garlicky odor
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copper functions
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needed for energy release and for utilization of iron in the body (helps to put iron onto hemoglobin, release iron from liver storage, absorption of iron in the intestines)
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copper deficiency
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could lead to defective iron mobilization leading to microcytic hypochromic anemia
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copper toxicity
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liver damage
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where is manganese generally present in the body
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bones
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functions of manganese
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formation of bones, also fat and carbohydrate metabolism
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manganese deficiency results in
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abnormal skeletal development
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manganese toxicity
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rare, but could be absorbed into the brain through the nasal olfactory route and lead to parkinson like symptoms
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flouride function
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strengthens teeth and prevents tooth decay
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fluoroapatite
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when fluoride becomes part of the tooth structure
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colorado brown stain
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due to high levels of fluoride in water in colorado
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fluorosis
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mild white spotting in teeth- can progress to brown spots and mottling
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fluoride toxicity
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problems with bone and possibly death (if extremely high dose)
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chromium functions
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activates insulin and facilitates the binding of insulin to cell receptors
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chromium deficiency
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insulin becomes less effective and impaired glucose tolerance (how quickly glucose is cleared from the blood after a meal), blood glucose remains high and insulin levels remain high
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