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30 Cards in this Set
- Front
- Back
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T/f Selenium is able to substitue for sulphur in sulphur containing amino acids?
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True
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In the diet, selenomethionine is generally derived from plants, or animals?
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plants
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In the diet, selenocysteine is generally derived from plants, or animals?
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animals
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List some organic compounds of selenium
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selenomethionine
selenocysteine selenocystine selenium-methyl selenomethionine |
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List some inorganic compounds of selenium
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selenite
selenate |
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T/F selenium is not well absorbed
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false
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Where does the majority of absorbtion of selenium occur?
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duodenum
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List some factors inhibiting absorption of selenium
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phytates
heavy metals |
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List some factors enhancing absorption of selenium
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vitamins A,C,and E
reduced glutathione in the intestinal lumen |
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How is selenium transported within the body?
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bound to transport proteins in the blood (VLDLs and LDLs)
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Where is the concentration of selenium highest in the body?
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kidney, liver, heart, pancreas, and muscle
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How is selenium excreted from the body?
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mainly via the urine and faeces
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What are the primary functions of selenium?
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it is necessary for the production of selenoproteins; selenium dependent enzymes (antioxidant, cell mediated immunity, anti-inflammatory)
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Which form of selenium is a component of selenoproteins?
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selenocysteine
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List some examples of selenoprotiens
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Glutathione Peroxidases
Thioredoxin reductase Selenoprotein P & W |
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What is the function of glutathione peroxidase?
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to reduce harmful free radicals to water and alcohol, helps maintain membrane integrity
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What is the function of thioredoxin reductase?
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regeneration of vit C
DNA synthesis regulation of gene expression |
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Is there a clinical deficiency for selenium?
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No
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Who is susceptible for suffering from selenium deficiency?
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alcoholics
Crohn's and Coeliac disease people with AIDs |
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What foods are the richest sources of selenium?
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organ meats
seafood muscle meats |
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What are some symptoms of long-term selenium supplementation over 1000mcg/day?
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fatigue, depression, arthritis, garlicky breath of body odour, irritability
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What are some compounds that sulphur is present as a part of?
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amino acids, glutathione, lipoic acid
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That is a thiol?
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a compound containing sulphur
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How is sulphur excreted?
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excreted as sulphate.
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What is the relationship between sulphur and high protein diets?
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Sulphate can bind iwth calcium ions in the glomerular filtrate & lead to increase in calcium urinary excretion
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What are the primary functions of compounds containing sulphur?
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structural entities
catalysts oxygen carriers hormones vitamins |
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What amino acids is sulphur present in?
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methionine, cystine, cysteine and taurine
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T/F: Sulphur is the elements that gives many key compounds their unique functional properties
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true
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Sulphur is a component of:
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co-enzymes
glutathione alpha-lipoic acids sulphur-containing amino acids |
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Is there any toxicity associated with sulphur?
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no
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