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144 Cards in this Set

  • Front
  • Back

Primary malnutrition

Due to inadequate dietary intake

Secondary malnutrition

Due to chronic disease

causes of malnutrition

social- child abuse


economic- poverty


biological- infection vomiting


environment- overcrowding

wellcome classification

measures the present or absent of edema


edema present is kwashiorkor


weight to age

marasmic

stunting and wasting

causes of kwashiorkor

Protein deficiency


aflatoxin


inflammation and oxidative stress


infection


late weaning

glutathione

Decrease in edema

causes of marasmus

Chronic energy deprivation


early weaning

features of marasmus

apathetic


muscle wasting


absence of subcutaneous fat


bone and skin appearance


sunken cheeks

features of kwashiorkor

pitting painless edema


hepatomegaly


abdominal distention


apathetic and irritability


dermatitis

meal planning for healthy eating

Staples


legumes


vegetables


fruits


animal products


less fat

food security

When all people at all times have physical and economical Asses to sufficient safe and nutritious food to meet their dietary need and food preferences for a active and healthy life

Low birth weight in children

develop obesity later in life

group at risk for food insecurity

marginal farmers


rural poor urban poor


unemployed


landless


femal headed household


elderly homeless


large household

policies and programs for food insecurity

1- growth monitoring and promation


2- nutrition clinic


3- program to reduce prevalence of anemia


4-target feeding program- school feeding


5- promoting breastfeeding


6- food stamps and food price subsidy


7- conditional cash transfer- PATH


8- nutrition education

growth monitoring and promation

identify individuals nutritionally at risk


early diagnosis of health problems


better targeting and intervention

nutrition clinic

refer malnourished children to hospital


counseling of malnourished and obese children

food law

1-protect the health of consumers


2-prevent consumer from being cheated


3-fair competition among traders


4-facilitate consumers to make healthy food choices

food and nutrition surveillance

Continous monitoring analysis and interpretation of food and nutrition situation with a country

uses of food and nutrition surveillance

depend on reliable data


program management


planning decision


direct funds to a particular nutritional problem


determine prevalence of malnutrition

data for food and nutrition surveillance

nutrition survey


secondary data (expensive)

brain development

First 5 years of life

Intra uterine growth retardation

Poor maternal nutrition and infection

supplementation for kids

Mike powder


cornmeal

stimulation for kids

weekly 1hr home visit

iodine defiency

Conginital hypothyroidism


mental retardation

zinc

cognitive and motor development

wernickes korsakoff syndrom cause

thamin defiency B1


increase alcohol

signs of wernickes korsakoff syndrom

ophthalmoplegia


nystagmus


ataxia of gait and stance


peripheral neuropathy


korsakoff psychosis

nutrition neuropathy cause

vitamin B12 deficiency

signs of nutrition neuropathy

impaired motor and sensory function


reduce or absent reflex activity


distal segment of extremity is more affected

nutrition amblyopia

Rare


visual impairment


peripheral vision intake


defiency of B vitamins

Cause of cerebellar degeneration

alcohol consumption

signs of cerebellar degeneration

Ataxia of stance and gait


improve nutrients and administration of B vitamins

pellagra cause

niacin B3 defiency


alcohol consumption

signs of pellagra

dementia


dermatitis


diarrhea


death

Florid psychosis

hallucination


disorientation


confusion

vitamin E defiency

abnormal lipid metabolism and malabsorption of vitamins

signs of vitamin E defiency

ophthalmoplegia


Ataxia


retinal dysfunction


myopathy

Wilson disease

autosomal recessive inheritance


cirrhosis


deficiency in ceruloplasmin


increase copper

vitamin B6 defiency pyridoxine

seizures

vitamin A excess

Use for acne


cause psuedotumor (Bening intracranial pressure)

cholin

Acetylcholine


egg liver soybean

phenylalanine

Dopamine


egg meat soybean beets almonds grains

tryptophan

serotonin


eggs milk cheese meat banana yogurts

Treatment for pellagra

niacin B3

Diabetes and nutrition.

to maintain insulin sensitivity

Diabetes cause

blindness


amputation


ESRD


myocardial infarction


stroke

exercise and insulin

improve insulin sensitivity

nutrition guidelines for carbohydrates in diabetics

whole grain


vegetables


fruits


low fat milk

older people and diabetes

encourage physical activity


multivitamin

insulin and weight

Increase weight


no CVS risk

cancer hallmark

1- unlimited cell replication


2- insensitive to growth inhibitor signal


3- evasion of Apoptosis


4- sustained angiogenises


5- invasion and metastasis


6- growth signal autonomy

causes of cancer

endogenous


exogenous


chance

Malnutrition

mismatch between intake and demand


imbalance between supply and demand

consequences of malnutrition

Increase mortality and morbidity


decrease immune competence and poor wound healing


psychological and cognitive effects


increase health care cost

Clinical nutrition management pathway

screening


assessment


treatment


monitoring and evaluation

albumin

No change in anorexia


acute phase protein

administration for malnutrition

enteral- mouth best


parenteral- IV central vein

carbohydrates source for malnutrition

dextrose

Protein source for malnutrition

crystalline AA


dipeptide

Fat source in malnutrition

Long chain fatty acid


soybean sunflower seed

types of parenteral nutrition

Central parenteral nutrition- central vein


high osmolarity


peripheral parenteral nutrition- peripheral vein

macronutrient

carbohydrates


fats


protein

Micronutrients

vitamins and minerals

Energy derived from fat

(g ×9)/energy intake

resting metabolic rate

Fall with age


higher in males compared to females


increase in active individuals


affected by thyroid hormone

Most variable component of energy expenditures

activity


20-30%

largest components of energy expenditure

BMR


70%

CO2 and O2 consumption

4.95kcal

weirs equation

Use to measure energy expenditures

Direct calorimetry

Measure heat

limitation of direct calorimetry

cost


technically demanding


infrequently use


confined nature

indirect calorimetry

Measure heat and energy


frequently use


estimate energy by respiratory gas

limitation of indirect calorimetry

Hyperventilation

doubly labeled water isotopes technique

1-Measure CO2 production


2-use H and O isotopes


3-urine saliva and plasma are sampled using mass spectrometeric analysis


4-difference between isotopes represent CO2 production


5-CO2 production is a result of Fat protein and carb

Physical activity level

Use to measure classification of lifestyle


TEE/REE

breast milk and cows milk

higher in carbohydrates and whey


lower in protein iron everything

indication of parenteral nutrition

GI failure


fistula


chrohns disease


sever pancreatitis


TPN administration

100 g glucose 5-7 min

complication of TPN

Infection


catheter related


metabolic

intermittent gastric feeding

aspiration


increase feed by 10ml for 12/24 hrs if patient is ill


flush tube with 30ml of water or Pepsi


inclin permitted


stomach functional

jejunostomy feeding

Continous


incline permitted


flush tube with 30ml of water or Pepsi

Reduce aspiration

feeding below the ligament of treitz


Continous


oral hygiene


posture

medication administration in TPN

crush meds and add water

immunonutrietion

arginine- increase macrophages


increase protein synthesis


increase NO

stress response to

surgery


trauma


sepsis


critical illness

systematic response to stress

Increase epinephrine cortisol ctytokins glucagon

local response to stress

matrix protein synthesis


wound repair

phases of stress response

ebb


flow/acute phase

ebb phase of stress response

immediately after injury


hypovolaemic


decrease cardiac output


decrease oxygen consumption


hypometabolism


increase sympathetic activity

flow/acute phase of stress response

hypermetabolic Increase REE temp


increase cardiac output


increase oxygen consumption


ctytokins mediated

mediators of stress

glucagon


cortisol


epinephrine

net result of mediators of stress

Increase protein mobilization


hyperglycemia


insulin resistance


increase lipolysis

ctytokins

TNF IL-1 IL- 6 IL-8


produced by the endothelial cells and immune cells

IL- 1

Fever


anorexia


hypotension


inflammation

TNF

catabolism


anorexia


increase hypothalamic - pituitary - adrenal axis

IL-6

act on othe ctytokins


activate hepatic acute phase reactants

Protein metabolism in stress

negative N balance


increase urea excretion


decrease LBM


decrease albumin

administration of protein.

2g/day

nucleotide

enhance humoral immunity


enhance macrophages

antioxidants

Decrease free radicals


vitamin A C E

sarcopenia

Decrease in lean body mass seen with aging


increase in fat mass

Hormones affecting calcium balance

calcitonin


growth hormone


prostaglandin


sex steroid


thyroid hormone


adrenal cortex hormone

nutrition factors associated with bone loss

sodium- hypercalciuria because your excretion sodium


protein


caffeine


alcohol- increase cortisol increase metabolism

vitamin D defiency

children- rickets


adults- osteomalacia


vitamin D calcium and phosphorous defiency


decrease sunlight exposure


growth plate not calcified bend due to weight

Clinical presentation of vitamin D defiency

Bone pain and tenderness


bone fracture


bone deformities

osteoporosis

Decrease bone mass


increase bone loss


Increase risk of death due to fracture

Low t score -2.5

osteoporosis

Estrogen defiency

Increase bone reabsorption and loss


Decrease Ca absorption by intestinal

recommend daily calcium intake

9-18 1300 mg


19- 50 1000 mg


50 up 1200 mg

Function of intestinal epithelium

barrier and immune function


protein synthesis


fluid and electrolyte secreation and absorption


mediator production


nutrients digestion and absorption

sodium absorption

colon- Na channel


small bowel- Na-H exchange Na dependent channels


luminal membrane- Na-glucose

potassium absorption

colon secrets potassium


recto - sigmoid absorption

chloride absorption

jejinum ilium


depend on HCO3 Ilium colon rectum

SGLT-1

Transport glucose in renal tubule


GLUT2

facilitated diffusion

peptidase

hydrolyzed peptide to di and tri peptide for absorption

symptom of dumping syndrom

hypotension


hypovolaemic


hypoglycemia

mild pancreatitis

enteral feeding

sever pancreatitis

DM


TPN

Short bowel syndrom

weight loss


diarrhea


malnutrition


steatorrhea(fat in stool)

Greater than 50% resection of colon

TPN then enteral

Greater than 75% resection of colon

TPN only

cancer cachexia

cachexia is seen in 60-70% of cancer patients


increase rate of malnutrition among hospital patient


cachexia and anorexia work together

causes of cancer cachexia

altered intake- depression


treatment


decrease absorption- GI tumor


altered metabolism

Energy expenditures and cancer

Increase REE


increase in lung and GIT cancer sarcoma

Protein metabolism in cancer

Decrease skeletal muscle mass


decrease LBM


decrease Protein synthesis

interferon gamma

Inhibit lipoprotein lipase


act with TNF to produce ctytokins

cancer cachexia management

Treat tumor


nutrition support


supplement


avoid fatty food


vitamins and minerals


no parenteral nutrition

EPA eicosapentanoic

fish oil


reduce inflammation


increase lean body mass

glutathione malnutrition

Decrease esophagitis

melatonin

Decrease enteritis

Cause of anorexia

genetic/families


temperment/personality


developmental factors


sciococultral influence

Clinical features of anorexia

weight loss


starvation


hide food


mood disturbance


hair loss


dry skin


low calorie diet


amenorrhea


fatigue depression


no breast

anorexia medical complication

Decrease in everything


muscle wasting


iron defiency anemia


hypothermia


impaired immune function


impaired renal function


impaired taste


osteoporosis


hypokalemia


decrease GI motility

management of anorexia

supplementation


difficult


patient must want to change


develop relationship with patient


start slow and go slow


1kg weekly weight gain to prevent fluid retention

refeeding syndrom

compartment shift in element


decrease elements


increase Mg excretion


affect every organ system


hypophosphonemia


hypernatremia

bulimia nervosa

Recurrent episode of Bing eating


trauma teased


late teens

purging

Vomiting


misuse of diuretics laxatives and emites


electrolyte imbalance

Non purging

excessive exercise


fasting

Abdominal fat ratio

waist to height ratio

anorexia nervosa

nervous loss of appetite


perfectionist obsesses high achiever

Case series

report generated about a individual or group or individual with the same diagnosis