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33 Cards in this Set
- Front
- Back
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vitamin K
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coag 2,7,9,10 factor synthesis
absorb in jejunum in presence of bile salts, hence bile duct obst, colonic microflora = vit K deficiency |
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fat soluble
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A, E, D, K
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Water soluble
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B'S, (7), Folic acid, C, Zinc, Copper, Chromium, Iodine, Fe, Manganese
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B-1
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Thiamine
Beriiberi, Wernicke's encephalopathy, |
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B-2
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Riboflavin, Cheilosis, seborrheic derm, angular stomatitis
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B-3
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Niacin, Pellagra, photo sens derm, diarrhea
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B-5
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Pantothenic Acid
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B-6
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Pyridoxine; CNS, seboor derm
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Biotin
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seborr derm
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B-12
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Cyanocobalamin; pernicious anemia, neural lesions
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Folic Acid
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Leukopenia, megaloblastic anemia, steatorrhea, sprue, glossitis
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Vit C
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retarded wound healing, scurvy, skin ulcers
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Zinc
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dermatitis, cerebelll dysfunction, abnl taste smell, depression
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copper
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anemia; water soluble
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obesity vs morbid obesity def
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120% ideal weight vs. 150%
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coag pathway: intrinsic
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12-11-9-8-5
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coag pathway extrinsic
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7-10
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coag pathway: intrinsic
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12-11-9-8-5
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common coag pathway
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10- 5- prothrombin to thrombin to act on fibrinogen to fibrin (loose) converted to (tight) by factor 8
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Pt evaluate which pathway and factors
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ability to form thrombin; extrinsic: 7, 10, 5. adequecy of prothrombin and fibrinogen
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APTT measures which pathway and factors?
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fibrinogen, prothombin, factors 5,8,9,10,11,12 in Intrinsic and commmon pathways. monitor heparin
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which PT or PTT normal in factor 7 def
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PTT
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coumadin therapy affects which PT or PTT and what factors involved
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PTT and factors 2, 9,10
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Prolonged Bleeding Time caused by
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thrombocytopenia, abnl platelet function (aspirin, granular platelet dis) or Von Willebrands dz
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Thrombin time is used to evaluate
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dic and chronic liver diz. also affect by heparin
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type A hemophilia
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dificiency of factor 8, males only, can be asymptomatic treated with factor 8 concentrates.
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hemophilia B, christmas disease
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defic. in factor 11.
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Von Willebrands treatment
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cryoprecipitate or DDAVP
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Liver dis coagulopathy
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inabil of liver to synthesize proteins and decreased prothrombin, factors 5,7,10 (but not 8)
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alcohol coagu
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acute thrombocytopenia
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coumadin
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depress 4 coag factors (2,7,9,10) prolonges both aptt, pt
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Heparin prolongs
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aptt and thrombin
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LMW heparin can
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bind antithrombin 3 and neutralize facotr Xa but not thrombin
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