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33 Cards in this Set

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vitamin K
coag 2,7,9,10 factor synthesis
absorb in jejunum in presence of bile salts, hence bile duct obst, colonic microflora = vit K deficiency
fat soluble
A, E, D, K
Water soluble
B'S, (7), Folic acid, C, Zinc, Copper, Chromium, Iodine, Fe, Manganese
B-1
Thiamine
Beriiberi, Wernicke's encephalopathy,
B-2
Riboflavin, Cheilosis, seborrheic derm, angular stomatitis
B-3
Niacin, Pellagra, photo sens derm, diarrhea
B-5
Pantothenic Acid
B-6
Pyridoxine; CNS, seboor derm
Biotin
seborr derm
B-12
Cyanocobalamin; pernicious anemia, neural lesions
Folic Acid
Leukopenia, megaloblastic anemia, steatorrhea, sprue, glossitis
Vit C
retarded wound healing, scurvy, skin ulcers
Zinc
dermatitis, cerebelll dysfunction, abnl taste smell, depression
copper
anemia; water soluble
obesity vs morbid obesity def
120% ideal weight vs. 150%
coag pathway: intrinsic
12-11-9-8-5
coag pathway extrinsic
7-10
coag pathway: intrinsic
12-11-9-8-5
common coag pathway
10- 5- prothrombin to thrombin to act on fibrinogen to fibrin (loose) converted to (tight) by factor 8
Pt evaluate which pathway and factors
ability to form thrombin; extrinsic: 7, 10, 5. adequecy of prothrombin and fibrinogen
APTT measures which pathway and factors?
fibrinogen, prothombin, factors 5,8,9,10,11,12 in Intrinsic and commmon pathways. monitor heparin
which PT or PTT normal in factor 7 def
PTT
coumadin therapy affects which PT or PTT and what factors involved
PTT and factors 2, 9,10
Prolonged Bleeding Time caused by
thrombocytopenia, abnl platelet function (aspirin, granular platelet dis) or Von Willebrands dz
Thrombin time is used to evaluate
dic and chronic liver diz. also affect by heparin
type A hemophilia
dificiency of factor 8, males only, can be asymptomatic treated with factor 8 concentrates.
hemophilia B, christmas disease
defic. in factor 11.
Von Willebrands treatment
cryoprecipitate or DDAVP
Liver dis coagulopathy
inabil of liver to synthesize proteins and decreased prothrombin, factors 5,7,10 (but not 8)
alcohol coagu
acute thrombocytopenia
coumadin
depress 4 coag factors (2,7,9,10) prolonges both aptt, pt
Heparin prolongs
aptt and thrombin
LMW heparin can
bind antithrombin 3 and neutralize facotr Xa but not thrombin