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16 Cards in this Set
- Front
- Back
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Vitamin A
Function Deficiency Excess Source |
Retinol
* Function * Constituents of visual pigments * Deficiency * Night blindness Dry Skin * Excess * Arthralgia Fatigue H/a Sore throat Alopecia * Source * Green Leafys |
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Vitamin B1
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Thiamine
* Function * Oxidative decarboxylation of alpha keptoacids Transketolase (HMP shunt) * Deficiency * Dry Beriberi: polyneuritis, muscle wasting Wet Beriberi: high output failure, edema Wernicke-Korsakoff: CNS Hemorrhagic lesions, confusion, ataxia, ophthalmoplegia, memory loss, confabulation |
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Vitamin B2
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Riboflavin
* Function * FADH2 (Redox) * Deficiency * Angular stomatitis Cheilosis Corneal vasculature |
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Vitamin B3
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Niacin
* Function * NAD/NADP * Deficiency * Pellagra: Diarrhea, Dermatitis, Dementia, Causes: Hartnup Dz (reduced trp abs) Malignant Carcinoid (trp metabolism INH (less B6) |
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Vitamin B5
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Pantothenate
* Function * Component of CoA Fatty acid synthase * Deficiency * Dermatitis Enteritis Alopecia Adrenal Insufficiency |
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Vitamin B6
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Pyridoxine
* Function * Transamination Decarboxylation Heme Synthesis * Deficiency * Convulsions Hyperirritability (inducible by INH and OCP) Peripheral neuropathy |
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Vitamin B12
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Cobalamine
* Function * Homocysteine methylation Methylmalonyl CoA handling * Deficiency * Megaloblastic anemia Optic neuropathy Paresthesias Glossitis * Causes * Sprue Enteritis Diphyllobothrium latum Pernicious anemia Crohn's Dz * Diagnostics * Schilling Test |
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Folic Acid
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* Deficiency *
Megaloblastic anemia without neuro Neural tube defects in fetus * Function * THF required for methylation Base synthesis |
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Biotin
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* Deficiency *
Dermatitis Enteritis * Carboxylation: Pyruvate --> oxaloacetate Acetyl CoA --> Malonyl CoA Proprionyl-CoA --> methylmalonyl CoA |
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Vitamin C
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* Deficiency *
Scurvy: swollen gums bruising anemia poor wound healing * Function * proline and lysine hydroxylation DA --> NE synthesis |
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Vitamin D
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* Deficiency *
Osteomalacia (children) Osteoporosis (adults) hypocalcemic tetany * Function * GI Ca uptake |
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Vitamin E
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* Deficiency *
Hemolysis Neurodysfunction * Function * Antioxidant |
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Vitamin K
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* Deficiency *
Bleeding * Function * Carboxylation of II, VII, IX, X, Protein C, Protein S |
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Zinc
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* Deficiency *
Delayed wound healing hypogonadism reduced hair |
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Kwashiorkor
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Protein deficit
Skin lesions edema Hepatic fatty change |
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Marasmus
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Total calorie deficiency
muscle wasting loss of sc fat edema |
