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9 Cards in this Set
- Front
- Back
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Secreted by muscle (heart and Skeletal) and adipose cells
Hydrolyzes TG from chylos and VLDL to FA and glycerol activated by apoC2 |
lipoprotein lipase (LPL)
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enzymes that hydrolyzes unsaturated FA from lipoprotein phospholipid and acylates cholesterol from CE in HDL
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Lecithin cholesterol acyl transferase
(LCAT) |
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Protein that exchanges TG and CE between HDL, VDL and IDL
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Cholesterol Ester Transfer Protein
(CETP) |
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synthesized in intestinal mucosal cells
transfers dietary TG and fat soluble vitamins through lymph to thoractic duct to blood |
Chylomicron
(chylo) |
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Chylo after much TG has been removed by LPL
Bimds to receptors (LDLR and LRP) present on liver cells |
chylomicron remnant
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synthesized in liver
transports TG to muscle and adipose TG hydrolyzed by LPL |
VLDL
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remnants of VLDL with much TG removed and with CE added (from HDL)
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IDL
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TG depleted VLDL
carries cholesterol ester binds to LDL-R via apoB100 2/3 removed by liver Half life 2-3 days; most C in blood is LDL Oxidized LDL removed via scavenger pathway in macrophages |
LDL
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Scavenges free cholesterol from membranes
cholesterol is esterfied (with FA from PC) by LCAT CEPT exchanges TG and CE between HDL, VLDL and IDL Carrier for extra A, C and E apoproteins in blood |
HDL
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