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9 Cards in this Set

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Name the indication, Action, & Adverse Effects Of:

Cefaclor
CEPHALOSPORIN

Tx of respiratory, dermatological, urinary tract, and middle ear infections.

Action: Inhibits the growth of bacterial cell walls causing cell death

Adverse Effects: N/V, diarrhea, rash, superinfection, bone marrow depression, risk for pseudomembranous colitis
Similar to Penicillins
4 Generations Exist Today
Name the indication, Action, & Adverse Effects Of:

Amoxicillin
PENICILLIN

Tx of infections caused by suceptible strains of bacteria, postexposure prophylaxis for anthrax, tx of Helicobacter infections as part of combination threapy

Actions: Inhibits synthesis of the cell wall in susceptible bacteria, causing cell death

Adverse Effects: N/V, diarrhea, glossitis, stomatitis, bone marrow suppression, rash, fever, superinfections, lethargy
Extended spectrum Penicillin
Name the indication, Action, & Adverse Effects Of:

Isoniazid
ANTIMYCOBACTERIAL

Tx of tuberculosis as part of combination therapy; prophylactic tx of household member of recently diagnoses tuberculosis

Actions: Interferes with lipid and nucleic acid synthesis in actively growing tubercle bacilli

Adverse Effects: peripheral neuropathies, N/V, hepatitis, bone marrow supression, fever, local irritation at injection site, gynecomastia, lupus syndrome
Name the indication, Action, & Adverse Effects Of:

Acyclovir
ANTIVIRAL

Tx of herpes simplex virus 1 & 2 infections; severe genital HSV; HSV encephalitis; acute tx of shingles & chickenpox

Action: Inhibits viral DNA replication

Adverse Effects: H.A., vertigo, tremors, N/V, rash
Name the indication, Action, & Adverse Effects Of:

Zidovudine
HIV/AIDS DRUG

Management of adults with symptomatic HIV infection in combination with other antiretovirals; prevention of maternal-fetal HIV transmission

Actions: A thymidine analogue that is activated to triphosphate form, which inhibits the replication of various retroviruses, including HIV

Adverse Effects: H.A., nausea, insomnia, diarrhea, fever, rash, bone marrow supression
Name the indication, Action, & Adverse Effects Of:

Fluconazole
ANTIFUNGAL

Tx of oropharyngeal, esophageal, and vanginal candidiasis; cryptococcal meningitis; systemis fungal infections; prophylaxis to decrease incidence of candidiasis in bone marrow transplants

Actions: Binds to sterols in fungal cell membrane, changing membrane permeability; fungicidal or fungistatic depending on concentration of drug and organism

Adverse Effects: H.A., N/V, diarrhea, ABD pain, rash
Name the indication, Action, & Adverse Effects Of:

Metronidazole
ANTIPROTOZOAL

Tx of acute intestinal amebiasis, amebic liver abscess, trichomoniasis, acute infections caused by susceptible strains of anaerobic bacteria, and preoperative and postoperative prophylaxis for pts undergoing colorectal surgery

Actions: INhibits DNA synthesis of specific anaerobes, causing cell death; mechanism of action as an antiprotozoal and amebicidal are not known

Adverse Effects: H.A., dizziness, ataxia, N/V, metallic taste, diarrhea, darkening of urine
Name the indication, Action, & Adverse Effects Of:

Bethanechol
CHOLINERGIC AGONIST

Ts of acute postoperative or postpartum non-obstructive urinary retention; neurogenic atony of the bladder with retention

Actions: acts directly on cholinergic receptors to mimic the effects of ACh; increases tone to detursor muscles and causes emptying of the bladder

Adverse Effects: ABD discomfort, salivation, N/V, sweating, flushing
Name the indication, Action, & Adverse Effects Of:

Atropine
ANTICHOLINERGIC AGENT

Indication: decrease secretions, bradycardia, pylorspasm, ureteral colic, relaxing of bladder, emotion lability with head injuries, antidote for cholinergic drugs, pupil dilation

Actions: Competitively blocks ACh muscarinic receptor sites, blocking the effects of the parasympathetic nervous system

Adverse Effects: blurred vision, mydriasis, cycloplegis, photophobia, palpitations, bradycardia, dry mouth, altered taste perception, urinary hesitancy and retention, decreased sweating, and predisposition to heat prostration