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18 Cards in this Set
- Front
- Back
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Isoniazid (INH)
adult daily dose |
5 mg/kg (300mg max daily)
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Isoniazid (INH)
side effects |
peripheral neuritis
hepatic enzyme elevation hepatitis hypersensitivity |
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Isoniazid (INH)
drug interactions |
Phenytoin-synergistic
Antabuse Alcohol |
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Isoniazid (INH)
remarks |
Bactericidal
Pyridoxine is used as prophylaxis for neuritis Monitor AST and ALT |
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Rifampin (Rifadin)
adult daily dose |
10 mg/kg (600mg max daily)
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Rifampin (Rifadin)
side effects |
hepatitis
febrile reaction purpura (rare) N/V |
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Rifampin (Rifadin)
drug interactions |
increases metabolism for oral contraceptives, corticosteroids, coumarin derivatives & methadone
digoxin |
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Rifampin (Rifadin)
remarks |
Bactericidal
orange urine & other body secretions discoloring of contact lenses monitor AST & ALT |
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Rifapentine (Priftin)
adult daily dose |
10 mg/kg (600mg twice weekly)
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Rifapentine (Priftin)
side effects |
hepatoxicity
thrombocytopenia |
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Rifapentine (Priftin)
drug interactions |
avoid protease inhibitors
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Rifapentine (Priftin)
remarks |
orange/red coloration of body secretions, contact lenses,
caution w elderly or w renal disease |
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Pyrazinamide
adult daily dose |
15-30 mg/kg (2.0 g max daily)
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Pyrazinamide
side effects |
hyperuricemmia
hepatoxicity skin rash arthralgias GI distress |
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Pyrazinamide
remarks |
Bactericidal
Monitor uric acid, AST, ALT |
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Ethambutol (Myambutol)
adult daily dose |
15-25 mg/kg (no max, but base on lean body weight
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Ethambutol (Myambutol)
side effects |
optic neuritis (blindness-rare)
skin rash |
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Ethambutol (Myambutol)
remarks |
Bacteriostatic
use w caution reneal disease or when eye testing is not feasible Monitor visual acuity, color discrimination |
