Nursing Iii-Parkinson's Meds

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Trihexyphenidyl hydrochloride (Apo-Trihex)

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Anticholingeric Agents

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Benztropine mesylate (Cogentin)

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Anticholingeric Agents

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Anticholingeric Agents indications

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-control tremor & rigidity
-counteract action of acetycholine

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Anticholingeric Agents common side effects

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-blurred vision, flushing rash, constipation, urinary retention, acute confusional states
-contraindicated in patients with narrow-angle glaucoma

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Amantadine hydrochloride (Symmetrel)

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Antiviral Agents

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Antiviral Agents indications

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reduce rigidity, tremor, bradykinesia, & postural changes in early Parkinson's disease

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Antiviral Agents common side effects

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psychiatric disturbances (mood changes, confusion, depression, hallucinations), lower extremity edema, urinary retention, visual impairment

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Bromocriptine mesylate (Parlodel)

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Dopamine Agonists

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Pergolide (Permax)

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Dopamine Agonists

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Ropinirole hydrochloride (Requip)

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Dopamine Agonists
(Nonergot Derivatives)

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Pramipexole (Mirapex)

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Dopamine Agonists
(Nonergot Derivatives)

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Dopamine Agonists indications

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Early Parkinson's
-secondary drug therapy after carbidopa or levodopa loses effectiveness

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Dopamine Agonists common side effects

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N/V, diarrhea, lightheadedness, hypotension, impotence, & psychiatric effects

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Dopamine Agonists (Nonergot Derivatives) indications

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early stages of Parkinson's

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Dopamine Agonists (Nonergot Derivatives) common side effects

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drowsiness or dizziness

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Selegiline (Eldepryl)

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Monoamine Oxidase Inhibitors

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Rasagiline (Azilect)

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Monoamine Oxidase Inhibitors

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Monoamine Oxidase Inhibitors indications

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Inhibit dopamine breakdown

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Monoamine Oxidase Inhibitors common side effects

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hypertensive crisis

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Entacapone (Comtan)

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Catechol-O-Methyltransferase Inhibitors

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Tolcapone (Tasmar)

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Catechol-O-Methyltransferase Inhibitors

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Tolcapone (Tasmar)

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Catechol-O-Methyltransferase Inhibitors

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Catechol-O-Methyltransferase Inhibitors indications

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increase duration of action of carbidopa or levodopa
-reduce motor fluctuations in patients w advanced Parkinson's

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Amitriptyline hydrochloride (Elavil)

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Antidepressants
(Tricyclic Antidepressants)

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Catechol-O-Methyltransferase Inhibitors indications

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increase duration of action of carbidopa or levodopa
-reduce motor fluctuations in patients w advanced Parkinson's

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Antidepressants
(Tricyclic Antidepressants) indications

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anticholinergic & antidepressant

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Amitriptyline hydrochloride (Elavil)

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Antidepressants
(Tricyclic Antidepressants)

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Antidepressants
(Tricyclic Antidepressants) common side effects

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hypertension, insomnia, dry mouth

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Antidepressants
(Tricyclic Antidepressants) indications

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anticholinergic & antidepressant

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Antidepressants
(Tricyclic Antidepressants) common side effects

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hypertension, insomnia, dry mouth

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Tolcapone (Tasmar)

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Catechol-O-Methyltransferase Inhibitors

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Catechol-O-Methyltransferase Inhibitors indications

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increase duration of action of carbidopa or levodopa
-reduce motor fluctuations in patients w advanced Parkinson's

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Amitriptyline hydrochloride (Elavil)

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Antidepressants
(Tricyclic Antidepressants)

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Antidepressants
(Tricyclic Antidepressants) indications

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anticholinergic & antidepressant

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Antidepressants
(Tricyclic Antidepressants) common side effects

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hypertension, insomnia, dry mouth

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Fluoxetine hydrochloride (Prozac)

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Antidepressants
(Serotonin Reuptake Inhibitors)

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Bupropion hydrochloride (Wellbutrin)

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Antidepressants
(Serotonin Reuptake Inhibitors)

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Antidepressants
(Serotonin Reuptake Inhibitors) indications

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antidepressant

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Antidepressants
(Serotonin Reuptake Inhibitors) common side effects

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clinical worsening & suicide risk

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Diphenhydramine hydrochloride (Benadryl)

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Antihistamines

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Orphenadrine citrate (Banflex)

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Antihistamines

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Phenindamine hydrochloride (Neo-Synephrine)

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Antihistamines

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Antihistamines indications

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may reduce tremors

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Antihistamines common side effects

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anticholinergic & sedative effects