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48 Cards in this Set
- Front
- Back
intracellular fluid
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40% of total body weight
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extracellular fluid
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20% of total body weight
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formula for plasma osmolarity
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2(Na) + BUN/5 + glucose/20
normal range is 275-295 milliosmoles/L |
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antidiuretic hormone - ADH
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Secreted by posterior pituitary in response to increased serum osmolarity
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Parathyroid hormone
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Secreted by parathyroid gland in response to low serum calcium
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Atrial natriuretic factor
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Released from cardiac muscle cells in response to atrial distention from fluid overload
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Aldosterone
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Secreted by the adrenal cortex in response to decreased blood volume, decreased renal perfusion, angiotensin
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renin
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secreted by kidneys in response to aldosterone
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angiotensinogen
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produced in liver, normally found in blood, acted upon by renin to form angiotensin
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angiotensin
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stimulates adrenal gland to produce aldosterone
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causes of hypovolemia
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excess urine output, diabetes insipidus, burns, fever, wound drainage, NG suction, diarrhea, vomiting, diuretics
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s/s of hypovolemia
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orthostatic changes, neg. I&O, fever, increased heart rate, weak thready pulses, weight loss
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isotonic fluid volume deficit
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fluid and electrolyte losses are equal
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In isotonic hypovolemia, what happens to EC and IC fluids?
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Volume & solute are lost from EC space; IC fluid unchanged
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Causes of isotonic hypovolemia
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Hemorrhage, diarrhea, decreased po intake, third spacing (trauma, burns, sepsis, cirrhosis)
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compensatory mechanisms for isotonic hypovolemia
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renin-angiotensin-aldosterone mechanism, SNS shunts blood to vital organs
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assessment of isotonic hypovolemia
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Increased Hgb and Hct
Na+ normal Urine SG >1.010 slightly conc. BUN increased |
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treatment for isotonic hypovolemia
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NS or LR, blood, albumin, antidiarrheals, increased PO intake and nutrition, ABX
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hypotonic hypovolemia
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solute loss is greater than fluid loss
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In hypotonic hypovolemia, what happens to EC and IC fluids?
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EC fluid hypotonic; EC fluid shifts to IC space, cells swell & lyse
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causes of hypotonic hypovolemia
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CRF, malnutrition, rehydration with hypotonic fluids
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compensatory mechanisms for hypotonic hypovolemia
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Renin-angiotensin-aldosterone mechasism, stim. by decr. arterial pressure
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assessment of hypotonic hypovolemia
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Increased Hgb & Hct
Na+ decreased Urine SG<1.010, slightly dilute |
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treatment for hypotonic hypovolemia
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NS or 3% saline w/ Lasix
K+, nutrition |
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Hypertonic fluid volume deficit
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Fluid loss greater than solute loss
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In hypertonic hypovolemia, what happens to EC and IC fluids?
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EC fluid hypertonic, IC fluid shifts to EC space, cell dehydrate
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Causes of hypertonic hypovolemia
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excess sweat, hyperventilation, fever, ketoacidosis, high osmolarity tube feeds
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compensatory mechanisms for hypertonic hypovolemia
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increased ADH (posterior pituitary stim by hyperosmolar ECF), increased thirst (hypothalamus)
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assessment of hypertonic hypovolemia
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Hgb & Hct normal or increased
Na+ increased Urine SG>1.030 more conc. |
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treatment for hypertonic hypovolemia
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1/2 NS, treat the cause (w/ insulin, antibiotics, tylenol...)
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causes of hypervolemia
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kidney probs, heart probs, corticosteroids, excess Na+ or fluid intake, hypotonic fluids, SIADH, low protein, venous return probs, immobility
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s/s of hypervolemia
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incr. HR, bounding pulses, incr. BP & CVP, JVD, dysrhthmias, incr. RR, dyspnea, moist crackles, skin cool & pale, edema, muscle weakness, diarrhea, ascites
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isotonic hypervolemia
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serum osmolarity is normal
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what happens to EC and IC fluids in isotonic hypervolemia?
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EC space is expanded
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causes of isotonic hypervolemia
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excess isotonic fluids infused, ingested, retained
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compensatory mechanisms for isotonic hypervolemia
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decr. ADH & aldosterone, incr. urine output
incr. natriuretic factor r/t atrial distension, incr. urine output |
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hypotonic hypervolemia
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AKA water intoxication, serum electrolytes decreased
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what happens to EC and IC fluids in hypotonic hypervolemia?
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hypotonic EC fluid moves into IC space, all compartments expand
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causes of hypotonic hypervolemia
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SIADH, excess water consumption
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hypertonic hypervolemia
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rare occurence, incr. serum osmolarity
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what happens to EC and IC fluids in hypertonic hypervolemia?
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IC fluid shifts to EC space; EC space expands, IC space contracts, cell shrivel
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causes of hypertonic hypervolemia
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excessive sodium intake
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treatments for hypervolemia
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caution with IV fluids, electrolyte solutions only, no free water, Lasix (furosemide)/Bumex (bumetanide), fluid restrictions
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What condition can result from too rapid IV infusions or blood transfusions?
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result - isotonic hypervolemia
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what is anasarca?
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generalized body edema from isotonic hypervolemia
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what are symptoms of anasarca?
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respiratory distress, weight gain, venous distension, incr. blood pressure
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what condition can results from intake of hypertonic fluids or extreme Na+ ingestion or retention (as from steroids or liver/rental failure)?
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result - hypertonic hypervolemia
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You see pitting edema and circulatory overload - what is the condition?
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dx - hypertonic hypovolemia
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