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6 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Hypopituitarism
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Disease of pituitary gland itself or of the hypothalamus
Complication of radiation therapy to head and neck area |
Result: Extreme weight loss, emaciation, atrophy of all endocrine glands/organs, hair loss, impotence, amenorrhea, hypometabolism, hypoglycemia
Coma and death occur if missing hormones are not replaced |
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Hypophysectomy
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Treat pituitary gland tumors
Cushing's syndrome (excessive ACTH) Menstruation ceases/infertility occurs |
Replacement therapy with corticosteroids and thyroid hormones is necessary
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Diabetes Insipidus - Overview
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Disorder of posterior lobe of pituitary gland
ADH deficency Polydipsia Large volumes of dilute urine |
May occur with meningitis, encephalitis, TB
Failure of renal tubules to respond to ADH - may be d/t hypokalemia, hypercalcemia and meds such as Lithium and Declomycin |
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Diabetes Insipidus - Clinical Manifestations
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Specific Gravity - 1.001-1.005
No abnormal substances Drinks 2-20 L of fluid/day |
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Fluid Deprivation test for Diabetes Insipidus
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Withhold fluids 8-12 hrs.
Weigh frequently during the test Unable to increase specific gravity and osmolality of urine Terminate if tachycardia, excessive weight loss, or hypotension develops |
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Diabetes Insipidus - Medical Management
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Replace ADH
Ensure adequate fluid replacement Identify underlying cause |
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